Use of thawed and washed red cells preserved in extended storage media for neonatal exchange transfusion

2019 ◽  
Vol 29 (2) ◽  
pp. 128-130
Author(s):  
M. R. Thomas ◽  
T. Bullock ◽  
G. S. Kendall ◽  
N. Win
PEDIATRICS ◽  
1951 ◽  
Vol 8 (1) ◽  
pp. 117-127
Author(s):  
ALEXANDER S. WIENER ◽  
IRVING B. WEXLER

A simplified method of treating erythroblastosis by exchange transfusion is described in which the patient is bled and simultaneously transfused with compatible packed red cells. A table is presented which gives the final hematocrit and percentage of inagglutinable red blood cells in the patient's body at the termination of the exchange transfusion, in relation to the patient's initial hematocrit and the amount of blood exchanged. An exchange transfusion with 100 to 150 cc. of packed cells appears to be adequate regardless of the severity of the anemia. Statistical analysis of the result of 106 exchange transfusions shows a progressive drop in mortality rate from 23.7% in 38 cases treated with 500 cc. of whole citrated blood, to 14.6 cc. in 48 cases treated with 1,000 cc. of whole citrated blood, and to 10.0% in 20 cases treated with 120 cc. of packed cells. While the improvement may be accidental, there is no doubt that exchange transfusion with packed cells is a simpler procedure which avoids the introduction into the patient's body of large amounts of adult plasma, and potentially toxic doses of citrate and calcium. Two cases are described in detail which have unusual serologic and clinical features and illustrate the types of problems which may arise when treating erythroblastotic babies.


PEDIATRICS ◽  
1968 ◽  
Vol 41 (6) ◽  
pp. 1128-1130
Author(s):  
Peter J. Dawson ◽  
S. Spence Meighan

In a search for evidence of a possible viral etiology for human leukemia, a comparison was made of the incidence of childhood leukemia among babies receiving exchange blood transfusion and those who had no such transfusion. During a 16-year period in the state of Oregon, no difference in the likelihood of contracting leukemia was detected between the two groups.


2021 ◽  
Author(s):  
Christie J. Bruno ◽  
Kristen M. Glass

Vox Sanguinis ◽  
2009 ◽  
Vol 97 (4) ◽  
pp. 358-358
Author(s):  
C. Phipps ◽  
J. Chay ◽  
M. Koh

2020 ◽  
Vol 59 (3) ◽  
pp. 102730 ◽  
Author(s):  
Min-Sun Kim ◽  
Yousun Chung ◽  
Hyungsuk Kim ◽  
Dae-Hyun Ko ◽  
Euiseok Jung ◽  
...  

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