Repeated courses of radiation treatment in an HER2‐positive breast cancer patient with diffuse brain metastases: A case report

2020 ◽  
Vol 26 (7) ◽  
pp. 1370-1371
Author(s):  
Sonia Silipigni ◽  
Edy Ippolito ◽  
Paolo Matteucci ◽  
Bianca Santo ◽  
Emma Gangemi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Brain Metastases ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
Radiation Treatment ◽  
Her2 Positive ◽  
Her2 Positive Breast Cancer ◽  
Diffuse Brain ◽  
Positive Breast Cancer

Retinal metastases treated with lapatinib (L) in a young HER2-positive breast cancer patient: Case report

2008 ◽  
Vol 26 (15_suppl) ◽  
pp. 12008-12008
Author(s):  
M. Sarti ◽  
O. Pagani ◽  
F. Bertoni ◽  
S. Longhi ◽  
C. Cafaro ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
Patient Case ◽  
Her2 Positive ◽  
Her2 Positive Breast Cancer ◽  
Positive Breast Cancer

scholarly journals Genotyping tumour DNA in cerebrospinal fluid and plasma of a HER2-positive breast cancer patient with brain metastases

ESMO Open ◽  
2017 ◽  
Vol 2 (4) ◽  
pp. e000253 ◽  
Author(s):  
Giulia Siravegna ◽  
Elena Geuna ◽  
Benedetta Mussolin ◽  
Giovanni Crisafulli ◽  
Alice Bartolini ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cerebrospinal Fluid ◽  
Brain Metastases ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
Her2 Positive ◽  
Her2 Positive Breast Cancer ◽  
Positive Breast Cancer

Trastuzumab prolongs overall survival in patients with brain metastases from Her2 positive breast cancer

2007 ◽  
Vol 85 (3) ◽  
pp. 311-317 ◽  
Author(s):  
Rupert Bartsch ◽  
Andrea Rottenfusser ◽  
Catharina Wenzel ◽  
Karin Dieckmann ◽  
Ursula Pluschnig ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Overall Survival ◽  
Brain Metastases ◽  
Her2 Positive ◽  
Her2 Positive Breast Cancer ◽  
Positive Breast Cancer

Integrative chemo-immune-radiological treatment of HER2 positive breast cancer combined with a review of potential microRNAs involved and analysis of experimental results from sub-THz vibrational spectroscopy

2021 ◽  
Vol 6 (12) ◽  
Keyword(s):  
Breast Cancer ◽  
Vibrational Spectroscopy ◽  
Radiation Treatment ◽  
Integrative Analysis ◽  
Micro Rna ◽  
Thz Spectroscopy ◽  
Her2 Positive ◽  
Her2 Positive Breast Cancer ◽  
Spectroscopic Signatures ◽  
Positive Breast Cancer

In this paper we present the results of a Breast Cancer study by integrative analysis of a NIH approved treatment for HER2 positive breast cancer. This study is combined with analysis of Micro-RNA involvement from application of sub-THz spectroscopy for visualization of molecules circulating in blood by measuring saliva. The combination of Taxol-Generic Name-Paclitaxel (PT-J9267) and Trastuzumab-ANNS 0/0 and KadcylaTM (Genetic Name Ado-Trastuzumab Emtansine) were used in 3-stages of combined chemotherapeutic and immune-treatments followed by Radiation treatment. The goal of using PT was to stop spread of the disease to other organs outside of the breast and under arm lymph nodes, as well as to shrink the size of the tumor to facilitate surgery and radiology in continuation of the treatment. Trastuzumab (TZ) was added to PT in the 2nd step to prevent the development of chemoresistance. Intravenous infusion of Kadcyla was used mainly to prevent metastasis. Integrative analysis of microRNA participation was conducted based on literature review and sub-Terahertz vibrational spectroscopy measurements of absorption spectra from samples taken weekly before and after each treatment, using Vibratess’ spectrometer. The results from sub-THz spectroscopy in this work demonstrate dramatical modification of spectroscopic signatures from patient samples following disease development and the initial steps in the course of treatment. These changes reflect the deep global regulation (reduction) of the initially participating microRNAs amounts and changes in the microRNAs contributing to the spectra.

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