scholarly journals Comparison of breast cancer incidence, clinicopathologic features, and risk factor prevalence in women aged 20‐29 at diagnosis to those aged 30‐39

2020 ◽  
Vol 26 (5) ◽  
pp. 1069-1070 ◽  
Author(s):  
Kristen E. Limbach ◽  
Enrique Leon ◽  
Rodney F. Pommier ◽  
SuEllen J. Pommier
2007 ◽  
Vol 9 (5) ◽  
Author(s):  
Theresa HM Keegan ◽  
Ellen T Chang ◽  
Esther M John ◽  
Pamela L Horn-Ross ◽  
Margaret R Wrensch ◽  
...  

2006 ◽  
Vol 98 (1) ◽  
pp. 45-55 ◽  
Author(s):  
Gertraud Maskarinec ◽  
Yang Zhang ◽  
Yumie Takata ◽  
Ian Pagano ◽  
Dianne M. Shumay ◽  
...  

2010 ◽  
Vol 28 (23) ◽  
pp. 3779-3783 ◽  
Author(s):  
Kavitha Passaperuma ◽  
Ellen Warner ◽  
Kimberley A. Hill ◽  
Anoma Gunasekara ◽  
Martin J. Yaffe

Purpose Increased mammographic breast density is well recognized as a breast cancer risk factor in the general population. However, it is unclear whether it is a risk factor in women with BRCA mutations. We present the results of a nested case-control screening study investigating the relationship between breast density and breast cancer incidence in this population. Patients and Methods Women ages 25 to 65 years with known BRCA mutations were enrolled onto a single-center, high-risk breast cancer screening program. Using a computer-aided technique (Cumulus), quantitative percentage density (PD) was measured for each participant on her baseline mammogram by a single, blinded observer. Results Between November 1997 and March 2008, 462 women (mean age, 44 years; 245 BRCA1 and 217 BRCA2) were screened and 50 breast cancers were diagnosed (38 invasive, 12 ductal carcinoma in situ [DCIS]). Density was not measured in 40 women of whom four developed cancer (three invasive, one DCIS). Mean PD (± standard deviation [SD]) for 376 women who did not develop breast cancer was 34% (23) compared with 31% (21) for 46 women with cancer (P = .51). Logistic regression model of breast cancer incidence and PD revealed an odds ratio of 0.99 (± 0.01 SD) for a one-unit increase in PD (P = .44). Results remained nonsignificant in multivariate analysis, as well as when women with pure DCIS were excluded. Conclusion Increased mammographic breast density is not associated with higher breast cancer incidence in women with BRCA mutations. On the basis of these findings, density should not be considered a factor for these women in decision making regarding prophylactic surgery or chemoprevention.


2017 ◽  
Vol 9 (1) ◽  
pp. 14
Author(s):  
Mellia Fransiska ◽  
Yulia Yulia

Breast cancer was a malignant disease due to the growth of abnormal cells in the breast can come from the mammary gland or supporting tissues such as fat and nerves. Based on Record Medical observation in Achmad Mochtar Hospital patients age ≥ 45 years who were breast cancer 2015-2016 as many as 372 people. The study aims to determine the risk factors of breast cancer incidence in elderly women. Research method of analytic study with the case-control approach, conducted in Poly Surgery and Inpatient Surgery Room Achmad Mochtar Hospital. Case population was elderly suffering from breast cancer recorded in data Record medical year 2016 counted 61 people. The samples were 42 (21 cases + 21 controls). The results of bivariate analysis of risk factors for breast cancer incidence in elderly women were family history (OR = 15) menarche age (OR = 8.5), and hormonal hormone use (OR = 15,438). family history, the age of menarche and the use of hormonal KB was a risk factor for breast cancer incidence and statistically, there was a significant relationship. It was suggested to the Hospital to provide counseling and counseling to female patients who checked themselves to Poly Surgery on the importance of breast cancer prevention efforts.


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