Metaplastic spindle cell carcinoma of the breast in a patient with neurofibromatosis type 1

2017 ◽  
Vol 24 (3) ◽  
pp. 391-394 ◽  
Author(s):  
Han Shin Lee ◽  
Eun Jung Jung ◽  
Ju Yeon Kim ◽  
Eun Jin Song ◽  
Chi Young Jeong ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Neurofibromatosis Type 1 ◽  
Spindle Cell ◽  
Neurofibromatosis Type ◽  
Spindle Cell Carcinoma ◽  
Carcinoma Of The Breast

Spindle cell carcinoma of the breast in a patient with neurofibromatosis type 1

2014 ◽  
Vol 24 (3) ◽  
pp. 397-398
Author(s):  
Megumi Nogimori ◽  
Kenji Yokota ◽  
Masaki Sawada ◽  
Takaaki Matsumoto ◽  
Michihiro Kono ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Neurofibromatosis Type 1 ◽  
Spindle Cell ◽  
Neurofibromatosis Type ◽  
Spindle Cell Carcinoma ◽  
Carcinoma Of The Breast

Spindle Cell Carcinoma of the Breast

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Yukiko Tokuda ◽  
Eun Sook Ko ◽  
Masahiro Yanagawa ◽  
Keiichiro Honma ◽  
Kenzo Shimazu ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Carcinoma Of The Breast

Spindle cell carcinoma of the breast: A case report and discussion

2012 ◽  
Vol 33 (3) ◽  
pp. 115-119 ◽  
Author(s):  
Zeina Nahleh ◽  
Vivian Ebrahim ◽  
Rose Guerrero ◽  
Sumit Gaur ◽  
Anoop Ayyappan ◽  
...  
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Carcinoma Of The Breast

scholarly journals Spindle cell carcinoma of the breast: Rare cancer with potentially targetable biomarkers

2019 ◽  
Vol 30 ◽  
pp. iii19 ◽  
Author(s):  
Z. Gatalica ◽  
S. Vranic ◽  
P. Stafford ◽  
J. Palazzo ◽  
F. Skenderi ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Rare Cancer ◽  
Carcinoma Of The Breast

scholarly journals Spindle cell carcinoma of the breast managed with neoadjuvant AIM: A case report

Rare Tumors ◽  
2020 ◽  
Vol 12 ◽  
pp. 203636132097702 ◽  
Author(s):  
April Choi ◽  
Philip M Carpenter ◽  
Shefali Chopra ◽  
Kristi M Lara ◽  
William W Tseng ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Cell Carcinoma ◽  
Randomized Trials ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Metaplastic Carcinoma ◽  
Cell Type ◽  
Carcinoma Of The Breast ◽  
Spindle Cell Type

Spindle cell carcinoma (SpC), also known as metaplastic carcinoma—spindle cell type, is a subtype of metaplastic carcinoma. Metaplastic carcinomas of the breast are rare but are thought to be more aggressive than invasive ductal carcinomas. Due to their rarity, there are few randomized trials that can inform any standardized approaches to treatment. Treatment is instead extrapolated from other types of breast cancer or metaplastic carcinomas of different locations. Here we present the first known case report of a patient with spindle cell carcinoma of the breast successfully treated with a standard sarcoma neoadjuvant regimen of doxorubicin, ifosfamide, and mesna (AIM) that resulted in >99% necrosis of the tumor and negative margins at the time of resection.

Low-Grade Fibromatosis-like Spindle Cell Carcinoma of the Breast

2015 ◽  
Vol 139 (4) ◽  
pp. 552-557 ◽  
Author(s):  
Jessica B. Dwyer ◽  
Beth Z. Clark
Keyword(s):  
Local Recurrence ◽  
Cell Carcinoma ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Definitive Diagnosis ◽  
Low Grade ◽  
Carcinoma Of The Breast ◽  
Complete Excision ◽  
Favorable Prognosis ◽  
Spindle Cells

Low-grade fibromatosis-like spindle cell carcinoma is a rare tumor in the breast, and represents a variant of the very heterogeneous group of metaplastic carcinomas of the breast. These tumors warrant distinction because of their resemblance to pure fibromatosis, their propensity for local recurrence, and their favorable prognosis among the metaplastic carcinomas of the breast. The diagnosis is potentially challenging, particularly on core needle biopsies, because of the morphologic overlap with other low-grade spindle cell lesions. Recognition of a proliferation of cytologically bland spindle cells with areas of epithelial differentiation in combination with immunohistochemistry using antibodies against cytokeratins and myoepithelial markers should aid in producing a definitive diagnosis. These tumors can be locally aggressive with an increased incidence of local recurrence, but the potential for lymph node or distant metastasis is low. Complete excision with adequate margins is considered curative in the majority of cases.

scholarly journals A Patient with Spindle Cell Carcinoma of the Breast who Had a Rapidly Downhill Course and Died 30 Days after Surgery—A Case Report—

2015 ◽  
Vol 76 (2) ◽  
pp. 245-249
Author(s):  
Takahiro INAISHI ◽  
Arihiro SHIBATA ◽  
Daishi MORIMOTO ◽  
Naohiro NOMURA ◽  
Tsunenobu TAKASE ◽  
...  
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Carcinoma Of The Breast
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