The Rightful Role of MRI after Negative Conventional Imaging in the Management of Bloody Nipple Discharge

2015 ◽  
Vol 22 (2) ◽  
pp. 209-212 ◽  
Author(s):  
Linda M. Sanders ◽  
Megan Daigle
Keyword(s):  
Nipple Discharge ◽  
Conventional Imaging ◽  
Bloody Nipple Discharge

scholarly journals Breast MRI in Patients with Unilateral Bloody and Serous-Bloody Nipple Discharge: A Comparison with Galactography

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Lucia Manganaro ◽  
Ilaria D’Ambrosio ◽  
Silvia Gigli ◽  
Francesca Di Pastena ◽  
Guglielmo Giraldi ◽  
...  
Keyword(s):  
Nipple Discharge ◽  
Breast Mri ◽  
Bloody Nipple Discharge ◽  
Ductal Cancer ◽  
Malignant Lesions ◽  
Mass Enhancement ◽  
Higher Sensitivity

Purpose. Assessing the role of breast MRI compared to galactography in patients with unilateral bloody or serous-bloody nipple discharge.Materials and Methods. Retrospective study including 53 unilateral discharge patients who performed galactography and MRI. We evaluated the capability of both techniques in identifying pathology and distinguishing between nonmalignant and malignant lesions. Lesions BIRADS 1/2 underwent follow-up, while the histological examination after surgery has been the gold standard to assess pathology in lesions BIRADS 3/4/5. The ROC analysis was used to test diagnostic MRI and galactography ability.Results. After surgery and follow-up, 8 patients had no disease (15%), 23 papilloma (43%), 11 papillomatosis (21%), 5 ductal cancer in situ (10%), and 6 papillary carcinoma (11%) diagnoses. Both techniques presented 100% specificity; MRI sensitivity was 98% versus 49% of galactography. Considering MRI, we found a statistical association between mass enhancement and papilloma (P<0.001; AUC 0.957; CI 0.888–1.025), ductal enhancement and papillomatosis (P<0.001; AUC 0.790; CI 0.623–0.958), segmental enhancement and ductal cancer in situ (P=0.007; AUC 0.750; CI 0.429–1.071), and linear enhancement and papillary cancer (P=0.011).Conclusions. MRI is a valid tool to detect ductal pathologies in patients with suspicious bloody or serous-bloody discharge showing higher sensitivity and specificity compared to galactography.

The Role of Galactography in the Detection of Breast Cancer

1988 ◽  
Vol 74 (2) ◽  
pp. 177-181 ◽  
Author(s):  
Stefano Ciatto ◽  
Patrizia Bravetti ◽  
Daniela Berni ◽  
Sandra Catarzi ◽  
Simonetta Bianchi
Keyword(s):  
Breast Cancer ◽  
Physical Examination ◽  
Benign Lesion ◽  
Nipple Discharge ◽  
Surgical Excision ◽  
Histologic Examination ◽  
Breast Cancers ◽  
Bloody Nipple Discharge ◽  
Low Incidence

The authors report on a series of 529 consecutive patients examined on physical examination, mammography, nipple discharge cytology and galactography. The criterion for galactography was essentially bloody nipple discharge (73% of cases). Serous nipple discharge was not considered worthy of routine galactography since it is associated with an extremely low incidence of breast cancer. Surgical excision and histologic examination of the discharging duct was performed in 200 cases. Eighteen cases of breast cancer were detected (10 infiltrating, 8 intraductal) of which 9, 6, 7 or 7 were suspected on physical examination, mammography, cytology or galactography, respectively. All combined tests suspected 13 of 18 breast cancers; 3 intraductal breast cancers were biopsied because of evidence of multiple papillomas on galactography, and 2 infiltrating breast cancers were operated because of persistent bloody nipple discharge in the absence of any other sign. No breast cancer was suspected on galactography alone. Galactography is indicated in the presence of bloody nipple discharge, and a biopsy should be performed when breast cancer or multiple papillomas are suspected. The diagnosis and excision of a single papilloma (breast cancer was never misdiagnosed as a single papilloma on galactography) is not worthwhile since a single papilloma is a benign lesion, and the benefit of its excision is still unclear.

Cystic Encapsulated Papillary Carcinoma in the Male Breast: An Unusual Feature With a Diagnostic Challenge

2021 ◽  
pp. 106689692110187
Author(s):  
Rongying Li ◽  
Karan Saluja ◽  
Brenda Mai ◽  
Michael Covinsky ◽  
Hongxia Sun
Keyword(s):  
Papillary Carcinoma ◽  
Cyst Wall ◽  
Correct Diagnosis ◽  
Nipple Discharge ◽  
Left Breast ◽  
Male Breast ◽  
Unusual Feature ◽  
Breast Mass ◽  
Repeat Biopsy ◽  
Bloody Nipple Discharge

Papillary carcinoma in the male breast is uncommon. Here, we report a case of a large encapsulated papillary carcinoma (EPC) in a 62-year-old male. The patient presented with a left breast mass of 1-year duration and bloody nipple discharge for several days. Mammography and breast ultrasonography showed a large left breast mass. The initial biopsy demonstrated fat necrosis with acute and chronic inflammation only. Due to clinical suspicion, a repeat biopsy was performed and revealed scant fragments of papillary carcinoma in a background of inflammation. The patient underwent left total mastectomy. Grossly, the breast contained a 9.0 cm entirely cystic lesion lined by a hemorrhagic thick fibrotic wall. No solid area was identified in the cyst. The entire cyst wall was examined under microscopy; only a few sections with papillary carcinoma were identified. The lesion was confined to the cyst wall; so, a diagnosis of EPC was made. Compared to the previously reported EPC cases of male breast, the lesion of this case was unusually cystic, which making the diagnosis challenging. Therefore, awareness of this unusual feature, repeat biopsy when the pathology result is discordant, and extensive sampling of the lesion are essential for making the correct diagnosis and guiding patient management.

Mammary ductoscopy and watchful follow-up substitute microdochectomy in patients with bloody nipple discharge

Breast Cancer ◽  
2014 ◽  
Vol 23 (2) ◽  
pp. 242-251 ◽  
Author(s):  
Masujiro Makita ◽  
Futoshi Akiyama ◽  
Naoya Gomi ◽  
Takuji Iwase
Keyword(s):  
Nipple Discharge ◽  
Bloody Nipple Discharge ◽  
Mammary Ductoscopy

scholarly journals Report of an 18-Month-Old Male Infant with Unilateral Bloody Nipple Discharge

2013 ◽  
Vol 7 (03) ◽  
pp. 154-155
Author(s):  
Asiye Safak Bulut ◽  
Levent Akgungor ◽  
Serdar Yuksel
Keyword(s):  
Nipple Discharge ◽  
Male Infant ◽  
Bloody Nipple Discharge

ULTRASOUND AS PRIME MODALITY OF CHOICE FOR EVALUATION OF BREAST LESIONS.

2021 ◽  
pp. 37-38
Author(s):  
Snehal Santosh Rathi ◽  
Sonali Mhaske Kadam
Keyword(s):  
High Frequency ◽  
Breast Imaging ◽  
Nipple Discharge ◽  
Signs And Symptoms ◽  
Breast Ultrasound ◽  
Breast Lesions ◽  
Medical College ◽  
Primary Screening ◽  
High Frequency Probe

INTRODUCTION: The four main roles of ultrasound in Breast imaging are-primary screening, supplemental screening, diagnosis and Interventional procedures. Palpable masses, abnormal nipple discharge and mammographic abnormalities constitute the most common indication for targeted Breast Ultrasound. AIM: To study the role of Ultrasound in evaluating Breast lesions and characterising them as Benign or Malignant. MATERIAL AND METHODS:This is a Retrospective analysis conducted in Department of Radiology, MGM Medical College and Hospital, Kamothey, Navi Mumbai from February 2021 to June 2021. A total of 136 patients with signs and symptoms related to breast lesions were screened. CONCLUSION: The advent of high frequency probe, easy accessibility, cost effectiveness, reliability and relatively easy to perform makes ultrasound as the prime modality of choice for screening breast lesions.

scholarly journals Bloody nipple discharge in infancy--report of two cases

2012 ◽  
Vol 2012 (jul19 1) ◽  
pp. bcr2012006649-bcr2012006649 ◽  
Author(s):  
M. Nascimento ◽  
A. Portela ◽  
F. Espada ◽  
M. Fonseca
Keyword(s):  
Nipple Discharge ◽  
Bloody Nipple Discharge

scholarly journals Breast Imaging During Pregnancy and Lactation

2019 ◽  
Vol 1 (4) ◽  
pp. 342-351
Author(s):  
Lisa Abramson ◽  
Lindsey Massaro ◽  
J Jaime Alberty-Oller ◽  
Amy Melsaether
Keyword(s):  
Breast Cancer ◽  
Breast Imaging ◽  
Treatment Options ◽  
Nipple Discharge ◽  
Cancer Staging ◽  
Imaging Features ◽  
Breast Cancers ◽  
Bloody Nipple Discharge ◽  
Breast Cancer Staging ◽  
Pregnancy And Lactation

Abstract Breast imaging during pregnancy and lactation is important in order to avoid delays in the diagnosis and treatment of pregnancy-associated breast cancers. Radiologists have an opportunity to improve breast cancer detection by becoming familiar with appropriate breast imaging and providing recommendations to women and their referring physicians. Importantly, during pregnancy and lactation, both screening and diagnostic breast imaging can be safely performed. Here we describe when and how to screen, how to work up palpable masses, and evaluate bloody nipple discharge. The imaging features of common findings in the breasts of pregnant and lactating women are also reviewed. Finally, we address breast cancer staging and provide a brief primer on treatment options for pregnancy-associated breast cancers.

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