Arguments against the Sentinel Lymph Node Biopsy for a Select Group of Invasive Breast Cancer Patients Suitable for Breast-Conserving Surgery and Adjuvant Systemic Therapy

2013 ◽  
Vol 19 (6) ◽  
pp. 680-682
Author(s):  
Rana M. Nadeem
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Cancer Patients ◽  
Breast Conserving Surgery ◽  
Lymph Node Biopsy ◽  
Breast Cancer Patients ◽  
Node Biopsy ◽  
Select Group

Axillary Regional Recurrence after Sentinel Lymph Node Biopsy for Breast Cancer

2006 ◽  
Vol 72 (10) ◽  
pp. 939-942
Author(s):  
David K. Rosing ◽  
Christine E. Dauphine ◽  
M. Perla Vargas ◽  
Katherine Gonzalez ◽  
Melissa Burla ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Cancer Patients ◽  
Axillary Dissection ◽  
Breast Conservation ◽  
Lymph Node Biopsy ◽  
Breast Cancer Patients ◽  
Node Biopsy

The accuracy of sentinel lymph node biopsy (SLNB) staging in breast cancer has been demonstrated in studies comparing it with axillary dissection. There is a 5 per cent false-negative rate, but this does not always correlate with axillary recurrence. Our purpose was to determine the rate of axillary lymphatic recurrence in breast cancer patients who had a negative SLNB. We conducted a cohort study of breast cancer patients who underwent SLNB between 2001 and 2005. Only patients who had a negative SLNB were included. Patient demographics and tumor factors were reviewed. Outcomes measured were axillary and systemic recurrence and survival. Eighty-nine patients with a mean age of 54.4 ± 9.9 years were included. Eighty-nine per cent of cases had infiltrating ductal carcinoma histology. Mean tumor size was 19 ± 14 mm. Breast conservation surgery was done in 65 cases and mastectomy in 24. A mean of 2.3 ± 2.4 SLN were found. After a median follow-up of 2.15 years, 1 (1%) patient developed a lymphatic recurrence in the axilla. SLNB provides accurate staging of breast cancer. Patients with negative SLNB do not require axillary dissection.

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