scholarly journals Feed safety collaborations: Experiences, progress and challenges

2021 ◽  
Author(s):  
Lisa Becton ◽  
Paul Davis ◽  
Paul Sundberg ◽  
Leah Wilkinson
Keyword(s):  
Feed Safety

scholarly journals Ten Years of Lateral Flow Immunoassay Technique Applications: Trends, Challenges and Future Perspectives

Sensors ◽  
2021 ◽  
Vol 21 (15) ◽  
pp. 5185
Author(s):  
Fabio Di Nardo ◽  
Matteo Chiarello ◽  
Simone Cavalera ◽  
Claudio Baggiani ◽  
Laura Anfossi
Keyword(s):  
Environmental Control ◽  
Improve Patient Care ◽  
Turnaround Time ◽  
Lateral Flow ◽  
Lateral Flow Immunoassay ◽  
Future Perspectives ◽  
Immunoassay Technique ◽  
Food And Feed ◽  
Application Fields ◽  
Feed Safety

The Lateral Flow Immunoassay (LFIA) is by far one of the most successful analytical platforms to perform the on-site detection of target substances. LFIA can be considered as a sort of lab-in-a-hand and, together with other point-of-need tests, has represented a paradigm shift from sample-to-lab to lab-to-sample aiming to improve decision making and turnaround time. The features of LFIAs made them a very attractive tool in clinical diagnostic where they can improve patient care by enabling more prompt diagnosis and treatment decisions. The rapidity, simplicity, relative cost-effectiveness, and the possibility to be used by nonskilled personnel contributed to the wide acceptance of LFIAs. As a consequence, from the detection of molecules, organisms, and (bio)markers for clinical purposes, the LFIA application has been rapidly extended to other fields, including food and feed safety, veterinary medicine, environmental control, and many others. This review aims to provide readers with a 10-years overview of applications, outlining the trends for the main application fields and the relative compounded annual growth rates. Moreover, future perspectives and challenges are discussed.

scholarly journals Processing Mixed Mesopelagic Biomass from the North-East Atlantic into Aquafeed Resources; Implication for Food Safety

Foods ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1265
Author(s):  
Marc H. G. Berntssen ◽  
Lars Thoresen ◽  
Sissel Albrektsen ◽  
Eduardo Grimaldo ◽  
Leif Grimsmo ◽  
...  
Keyword(s):  
Food Safety ◽  
Transfer Model ◽  
Farmed Fish ◽  
Fluoride Level ◽  
North East ◽  
The North ◽  
Variable Species ◽  
Feed Safety ◽  
Global Population ◽  
Aquafeed Ingredients

Aquaculture produces most of the world’s seafood and is a valuable food source for an increasing global population. Low trophic mesopelagic biomasses have the potential to sustainably supplement aquafeed demands for increased seafood production. The present study is a theoretical whole-chain feed and food safety assessment on ingredients from mesopelagic biomass and the resulting farmed fish fed these ingredients, based on analysis of processed mesopelagic biomass. Earlier theoretical estimations have indicated that several undesirable compounds (e.g., dioxins and metals and fluoride) would exceed the legal maximum levels for feed and food safety. Our measurements on processed mesopelagic biomasses show that only fluoride exceeds legal feed safety limits. Due to high levels of fluoride in crustaceans, their catch proportion will dictate the fluoride level in the whole biomass and can be highly variable. Processing factors are established that can be used to estimate the levels of undesirables in mesopelagic aquafeed ingredients from highly variable species biomass catches. Levels of most the studied undesirables (dioxins, PCBs, organochlorine pesticides, brominated flame retardant, metals, metalloids) were generally low compared to aquafeed ingredients based on pelagic fish. Using a feed-to-fillet aquaculture transfer model, the use of mesopelagic processed aquafeed ingredients was estimated to reduce the level of dioxins and PCBs by ~30% in farmed seafood such as Atlantic salmon.

scholarly journals Occurrence, Impact on Agriculture, Human Health, and Management Strategies of Zearalenone in Food and Feed: A Review

Toxins ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 92
Author(s):  
Dipendra Kumar Mahato ◽  
Sheetal Devi ◽  
Shikha Pandhi ◽  
Bharti Sharma ◽  
Kamlesh Kumar Maurya ◽  
...  
Keyword(s):  
Human Health ◽  
Control Strategies ◽  
Management Strategies ◽  
Structural Similarity ◽  
Fungal Metabolites ◽  
Natural Estrogens ◽  
Food And Feed ◽  
Feed Safety ◽  
And Control ◽  
Different Sources

Mycotoxins represent an assorted range of secondary fungal metabolites that extensively occur in numerous food and feed ingredients at any stage during pre- and post-harvest conditions. Zearalenone (ZEN), a mycotoxin categorized as a xenoestrogen poses structural similarity with natural estrogens that enables its binding to the estrogen receptors leading to hormonal misbalance and numerous reproductive diseases. ZEN is mainly found in crops belonging to temperate regions, primarily in maize and other cereal crops that form an important part of various food and feed. Because of the significant adverse effects of ZEN on both human and animal, there is an alarming need for effective detection, mitigation, and management strategies to assure food and feed safety and security. The present review tends to provide an updated overview of the different sources, occurrence and biosynthetic mechanisms of ZEN in various food and feed. It also provides insight to its harmful effects on human health and agriculture along with its effective detection, management, and control strategies.

FUSARIUM-ID v.3.0: An updated, downloadable resource for Fusarium species identification

Plant Disease ◽  
2021 ◽  
Author(s):  
Terry Torres-Cruz ◽  
Briana Whitaker ◽  
Robert Proctor ◽  
Kirk Broders ◽  
Imane Laraba ◽  
...  
Keyword(s):  
Sequence Data ◽  
Safety Concern ◽  
Fusarium Species ◽  
Elongation Factor ◽  
Sequence Database ◽  
Accurate Identification ◽  
Dna Sequence Data ◽  
Species Complexes ◽  
Marker Loci ◽  
Feed Safety

Species within Fusarium are of global agricultural, medical, and food/feed safety concern and have been extensively characterized. However, accurate identification of species is challenging and usually requires DNA sequence data. FUSARIUM-ID (http://isolate.fusariumdb.org/) is a publicly available database designed to support the identification of Fusarium species using sequences of multiple phylogenetically informative loci, especially the highly informative ~680 bp 5' portion of the translation elongation factor 1-alpha (TEF1) gene that has been adopted as the primary barcoding locus in the genus. However, FUSARIUM-ID v.1.0 and 2.0 had several limitations, including inconsistent metadata annotation for the archived sequences and poor representation of some species complexes and marker loci. Here, we present FUSARIUM-ID v.3.0, which provides the following improvements: (i) additional and updated annotation of metadata for isolates associated with each sequence, (ii) expanded taxon representation in the TEF1 sequence database, (iii) availability of the sequence database as a downloadable file to enable local BLAST queries, and (iv) a tutorial file for users to perform local BLAST searches using either freely-available software, such as SequenceServer, BLAST+ executable in the command line, and Galaxy, or the proprietary Geneious software. FUSARIUM-ID will be updated on a regular basis by archiving sequences of TEF1 and other loci from newly identified species and greater in-depth sampling of currently recognized species.

scholarly journals Food and feed safety: Cases and approaches to identify the responsible toxins and toxicants

Food Control ◽  
2019 ◽  
Vol 98 ◽  
pp. 9-18 ◽  
Author(s):  
Arjen Gerssen ◽  
Toine H.F. Bovee ◽  
Leendert A. van Ginkel ◽  
Marlou L.P.S. van Iersel ◽  
Ron L.A.P. Hoogenboom
Keyword(s):  
Food And Feed ◽  
Safety Cases ◽  
Feed Safety ◽  
Food And Feed Safety

Phylogenetic Diversity and Mycotoxin Potential of Emergent Phytopathogens within the Fusarium tricinctum Species Complex

2022 ◽  
Author(s):  
Imane Laraba ◽  
Mark Busman ◽  
David M. Geiser ◽  
Kerry O'Donnell
Keyword(s):  
Species Complex ◽  
Phylogenetic Diversity ◽  
Agricultural Research ◽  
Distinct Species ◽  
Culture Collections ◽  
Strain Collection ◽  
Food And Feed ◽  
Feed Safety ◽  
Large Survey ◽  
Fusarium Tricinctum

Recent studies on multiple continents indicate members of the Fusarium tricinctum species complex (FTSC) are emerging as prevalent pathogens of small-grain cereals, pulses, and other economically important crops. These understudied fusaria produce structurally diverse mycotoxins, among which enniatins (ENNs) and moniliformin (MON) are the most frequent and of greatest concern to food and feed safety. Herein a large survey of fusaria in the Fusarium Research Center and Agricultural Research Service culture collections was undertaken to assess species diversity and mycotoxin potential within the FTSC. A 151-strain collection originating from diverse hosts and substrates from different agroclimatic regions throughout the world was selected from 460 FTSC strains to represent the breadth of FTSC phylogenetic diversity. Evolutionary relationships inferred from a 5-locus dataset, using maximum likelihood and parsimony, resolved the 151 strains as 24 phylogenetically distinct species, including nine that are new to science. Of the five genes analyzed, nearly full-length phosphate permease sequences contained the most phylogenetically informative characters, establishing its suitability for species-level phylogenetics within the FTSC. Fifteen of the species produced ENNs, MON, the sphingosine analog 2-amino-14,16- dimethyloctadecan-3-ol (AOD), and the toxic pigment aurofusarin (AUR) on a cracked corn kernel substrate. Interestingly, the five earliest diverging species in the FTSC phylogeny (i.e., F. iranicum, F. flocciferum, F. torulosum, Fusarium spp. FTSC 8 and 24) failed to produce AOD and MON, but synthesized ENNs and/or AUR. Moreover, our reassessment of nine published phylogenetic studies on the FTSC identified 11 additional novel taxa, suggesting this complex comprises at least 36 species.

Reference on Mycotoxins Occurrence, Prevalence, and Risk Assessment in Food Systems

2019 ◽  
pp. 294-343
Author(s):  
Griffiths Atungulu ◽  
Zeinab Mohammadi-Shad
Keyword(s):  
Risk Assessment ◽  
Filamentous Fungi ◽  
Human Exposure ◽  
Food Systems ◽  
Economic Losses ◽  
Animal Products ◽  
Food And Feed ◽  
Feed Safety ◽  
And Storage ◽  
Food And Feed Safety

Mycotoxins are a group of naturally occurring toxins that are produced by different filamentous fungi genera such as Aspergillus, Penicillium, Fusarium, etc. The word mycotoxin literally is derived from Greek word “myke” meaning fungus and “toxicum” meaning toxin. These contaminants can develop on different food and feed commodities during different stages including pre-harvest, harvest, and storage. Mycotoxins are of concern because their outbreak result in animal and human diseases and economic losses. It has been estimated that global post-harvest losses are approximately at 50%. Human exposure to mycotoxins is typically through consumption of contaminated agricultural products or indirectly by consumption of animal products containing mycotoxins or their metabolites. The chapter provides the latest information on mycotoxin issues and challenges related to food and feed safety.

scholarly journals An In Silico Target Fishing Approach to Identify Novel Ochratoxin A Hydrolyzing Enzyme

Toxins ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 258 ◽  
Author(s):  
Luca Dellafiora ◽  
Christoph Gonaus ◽  
Barbara Streit ◽  
Gianni Galaverna ◽  
Wulf-Dieter Moll ◽  
...  
Keyword(s):  
Ochratoxin A ◽  
In Silico ◽  
Fungal Species ◽  
Mitigation Strategies ◽  
Carboxypeptidase B ◽  
Enzymatic Assays ◽  
Food And Feed ◽  
Hydrolyzing Enzymes ◽  
Feed Safety

Ochratoxin A (OTA), a mycotoxin that is of utmost concern in food and feed safety, is produced by fungal species that mainly belong to the Aspergillus and Penicillium genera. The development of mitigation strategies to reduce OTA content along the supply chains is key to ensuring safer production of food and feed. Enzyme-based strategies are among the most promising methods due to their specificity, efficacy, and multi-situ applicability. In particular, some enzymes are already known for hydrolyzing OTA into ochratoxin alpha (OTα) and phenylalanine (Phe), eventually resulting in detoxification action. Therefore, the discovery of novel OTA hydrolyzing enzymes, along with the advancement of an innovative approach for their identification, could provide a broader basis to develop more effective mitigating strategies in the future. In the present study, a hybrid in silico/in vitro workflow coupling virtual screening with enzymatic assays was applied in order to identify novel OTA hydrolyzing enzymes. Among the various hits, porcine carboxypeptidase B was identified for the first time as an effective OTA hydrolyzing enzyme. The successful experimental endorsement of findings of the workflow confirms that the presented strategy is suitable for identifying novel OTA hydrolyzing enzymes, and it might be relevant for the discovery of other mycotoxin- mitigating enzymes.

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