Pathogenesis and genetic characteristics of a novel reassortant low pathogenic avian influenza A(H7N6) virus isolated in Cambodia in 2019

2021 ◽  
Author(s):  
Yu‐Na Lee ◽  
Dong‐Hun Lee ◽  
Jae‐In Shin ◽  
Young‐Jae Si ◽  
Ji‐Ho Lee ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A ◽  
Genetic Characteristics ◽  
Pathogenic Avian Influenza ◽  
Low Pathogenic Avian Influenza

scholarly journals Susceptibility of rock doves to low-pathogenic avian influenza A viruses

2015 ◽  
Vol 161 (3) ◽  
pp. 715-720 ◽  
Author(s):  
Susan A. Shriner ◽  
J. Jeffrey Root ◽  
Nicole L. Mooers ◽  
Jeremy W. Ellis ◽  
Scott R. Stopak ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A ◽  
Influenza A Viruses ◽  
Pathogenic Avian Influenza ◽  
Low Pathogenic Avian Influenza

Low pathogenic avian influenza A(H7N9) virus causes high mortality in ferrets upon intratracheal challenge: A model to study intervention strategies

Vaccine ◽  
2013 ◽  
Vol 31 (43) ◽  
pp. 4995-4999 ◽  
Author(s):  
J.H.C.M. Kreijtz ◽  
E.J.B. Veldhuis Kroeze ◽  
K.J. Stittelaar ◽  
L. de Waal ◽  
G. van Amerongen ◽  
...  
Keyword(s):  
Avian Influenza ◽  
High Mortality ◽  
Influenza A ◽  
Intervention Strategies ◽  
H7n9 Virus ◽  
Pathogenic Avian Influenza ◽  
Low Pathogenic Avian Influenza ◽  
Study Intervention

scholarly journals H7N9: a low pathogenic avian influenza A virus infecting humans

2014 ◽  
Vol 5 ◽  
pp. 91-97 ◽  
Author(s):  
Jun Liu ◽  
Haixia Xiao ◽  
Yan Wu ◽  
Di Liu ◽  
Xiaopeng Qi ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A Virus ◽  
Influenza A ◽  
Pathogenic Avian Influenza ◽  
Avian Influenza A Virus ◽  
Low Pathogenic Avian Influenza

Erythrocyte binding preference of 16 subtypes of low pathogenic avian influenza and 2009 pandemic influenza A (H1N1) viruses

2010 ◽  
Vol 146 (3-4) ◽  
pp. 346-349 ◽  
Author(s):  
Witthawat Wiriyarat ◽  
Hatairat Lerdsamran ◽  
Phisanu Pooruk ◽  
Robert G. Webster ◽  
Suda Louisirirotchanakul ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Pathogenic Avian Influenza ◽  
Binding Preference ◽  
Influenza A H1n1 ◽  
Erythrocyte Binding ◽  
Low Pathogenic Avian Influenza

scholarly journals Insertion of a Multibasic Cleavage Motif into the Hemagglutinin of a Low-Pathogenic Avian Influenza H6N1 Virus Induces a Highly Pathogenic Phenotype

2010 ◽  
Vol 84 (16) ◽  
pp. 7953-7960 ◽  
Author(s):  
Vincent J. Munster ◽  
Eefje J. A. Schrauwen ◽  
Emmie de Wit ◽  
Judith M. A. van den Brand ◽  
Theo M. Bestebroer ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Virus Replication ◽  
Influenza A ◽  
Virus Genotype ◽  
Specific Nature ◽  
Highly Pathogenic ◽  
Pathogenic Avian Influenza ◽  
Low Pathogenic Avian Influenza

ABSTRACT The highly pathogenic avian influenza (HPAI) virus phenotype is restricted to influenza A viruses of the H5 and H7 hemagglutinin (HA) subtypes. To obtain more information on the apparent subtype-specific nature of the HPAI virus phenotype, a low-pathogenic avian influenza (LPAI) H6N1 virus was generated, containing an HPAI H5 RRRKKR↓G multibasic cleavage site (MBCS) motif in HA (the downward arrow indicates the site of cleavage). This insertion converted the LPAI virus phenotype into an HPAI virus phenotype in vitro and in vivo. The H6N1 virus with an MBCS displayed in vitro characteristics similar to those of HPAI H5 viruses, such as cleavage of HA0 (the HA protein of influenza A virus initially synthesized as a single polypeptide precursor) and virus replication in the absence of exogenous trypsin. Studies of chickens confirmed the HPAI phenotype of the H6N1 virus with an MBCS, with an intravenous pathogenicity index of 1.4 and systemic virus replication upon intranasal inoculation, the hallmarks of HPAI viruses. This study provides evidence that the subtype-specific nature of the emergence of HPAI viruses is not at the molecular, structural, or functional level, since the introduction of an MBCS resulted in a fully functional virus with an HPAI virus genotype and phenotype.

scholarly journals Low Pathogenic Avian Influenza A (H5N7) Virus Isolated from a Domestic Duck in Dongting Lake Wetland of China, 2016

2019 ◽  
Vol 34 (1) ◽  
pp. 97-101 ◽  
Author(s):  
Liping Ma ◽  
Haizhou Liu ◽  
Runkun Wang ◽  
Tao Jin ◽  
Di Liu ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A ◽  
Dongting Lake ◽  
Domestic Duck ◽  
Pathogenic Avian Influenza ◽  
Low Pathogenic Avian Influenza

Sampling for low-pathogenic avian influenza A virus in wild Mallard ducks: Oropharyngeal versus cloacal swabbing

Vaccine ◽  
2008 ◽  
Vol 26 (35) ◽  
pp. 4414-4416 ◽  
Author(s):  
Patrik Ellström ◽  
Neus Latorre-Margalef ◽  
Petra Griekspoor ◽  
Jonas Waldenström ◽  
Jenny Olofsson ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A Virus ◽  
Influenza A ◽  
Pathogenic Avian Influenza ◽  
Avian Influenza A Virus ◽  
Low Pathogenic Avian Influenza ◽  
Wild Mallard
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