Phylogenetic and Phylodynamic Analysis of a Classical Swine Fever Virus Outbreak in Japan (2018–2020)

2021 ◽  
Author(s):  
Kotaro Sawai ◽  
Tatsuya Nishi ◽  
Katsuhiko Fukai ◽  
Tomoko Kato ◽  
Yoko Hayama ◽  
...  
Keyword(s):  
Classical Swine Fever Virus ◽  
Classical Swine Fever ◽  
Fever Virus ◽  
Phylodynamic Analysis

ARFGAP1 binds to classical swine fever virus NS5A protein and enhances CSFV replication in PK-15 cells

2021 ◽  
Vol 255 ◽  
pp. 109034
Author(s):  
Liang Zhang ◽  
Mingxing Jin ◽  
Mengzhao Song ◽  
Shanchuan Liu ◽  
Tao Wang ◽  
...  
Keyword(s):  
Classical Swine Fever Virus ◽  
Classical Swine Fever ◽  
Fever Virus ◽  
Ns5a Protein

Genome Variability of Classical Swine Fever Virus during the 2018–2020 Epidemic in Japan

2021 ◽  
pp. 109128
Author(s):  
Tatsuya Nishi ◽  
Katsuhiko Fukai ◽  
Tomoko Kato ◽  
Kotaro Sawai ◽  
Takehisa Yamamoto
Keyword(s):  
Classical Swine Fever Virus ◽  
Classical Swine Fever ◽  
Fever Virus ◽  
Genome Variability

scholarly journals A Novel E2 Glycoprotein Subunit Marker Vaccine Produced in Plant Is Able to Prevent Classical Swine Fever Virus Vertical Transmission after Double Vaccination

Vaccines ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 418
Author(s):  
Youngmin Park ◽  
Yeonsu Oh ◽  
Miaomiao Wang ◽  
Llilianne Ganges ◽  
José Alejandro Bohórquez ◽  
...  
Keyword(s):  
Vertical Transmission ◽  
Classical Swine Fever Virus ◽  
Neutralizing Antibodies ◽  
Subunit Vaccine ◽  
Vaccine Dose ◽  
Classical Swine Fever ◽  
Fever Virus ◽  
Tissue Samples ◽  
Marker Vaccine ◽  
E2 Glycoprotein

The efficacy of a novel subunit vaccine candidate, based in the CSFV E2 glycoprotein produced in plants to prevent classical swine fever virus (CSFV) vertical transmission, was evaluated. A Nicotiana benthamiana tissue culture system was used to obtain a stable production of the E2-glycoprotein fused to the porcine Fc region of IgG. Ten pregnant sows were divided into three groups: Groups 1 and 2 (four sows each) were vaccinated with either 100 μg/dose or 300 μg/dose of the subunit vaccine at 64 days of pregnancy. Group 3 (two sows) was injected with PBS. Groups 1 and 2 were boosted with the same vaccine dose. At 10 days post second vaccination, the sows in Groups 2 and 3 were challenged with a highly virulent CSFV strain. The vaccinated sows remained clinically healthy and seroconverted rapidly, showing efficient neutralizing antibodies. The fetuses from vaccinated sows did not show gross lesions, and all analyzed tissue samples tested negative for CSFV replication. However, fetuses of non-vaccinated sows had high CSFV replication in tested tissue samples. The results suggested that in vaccinated sows, the plant produced E2 marker vaccine induced the protective immunogenicity at challenge, leading to protection from vertical transmission to fetuses.

scholarly journals Classical swine fever virus employs the PERK- and IRE1-dependent autophagy for viral replication in cultured cells.

Virulence ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 130-149
Author(s):  
Erpeng Zhu ◽  
Huawei Wu ◽  
Wenxian Chen ◽  
Yuwei Qin ◽  
Jiameng Liu ◽  
...  
Keyword(s):  
Viral Replication ◽  
Classical Swine Fever Virus ◽  
Cultured Cells ◽  
Classical Swine Fever ◽  
Fever Virus

Genetic heterogeneity of classical swine fever virus in Central Europe

1997 ◽  
Vol 52 (2) ◽  
pp. 195-204 ◽  
Author(s):  
T Stadejek ◽  
Š Vilček ◽  
J.P Lowings ◽  
A Ballagi-Pordány ◽  
D.J Paton ◽  
...  
Keyword(s):  
Central Europe ◽  
Genetic Heterogeneity ◽  
Classical Swine Fever Virus ◽  
Classical Swine Fever ◽  
Fever Virus

Phylogenetic analysis of recent isolates of classical swine fever virus from Colombia

2006 ◽  
Vol 115 (1) ◽  
pp. 99-103 ◽  
Author(s):  
Zonia Yubyll Sabogal ◽  
José Darío Mogollón ◽  
Maria Antonia Rincón ◽  
Alfonso Clavijo
Keyword(s):  
Phylogenetic Analysis ◽  
Classical Swine Fever Virus ◽  
Classical Swine Fever ◽  
Fever Virus
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