Epidemiological investigation of the novel genotype avian hepatitis E virus and co‐infected immunosuppressive viruses in farms with hepatic rupture haemorrhage syndrome, recently emerged in China

2018 ◽  
Vol 66 (2) ◽  
pp. 776-784 ◽  
Author(s):  
Qi Su ◽  
Yawen Zhang ◽  
Yang Li ◽  
Zhizhong Cui ◽  
Shuang Chang ◽  
...  
Keyword(s):  
Hepatitis E Virus ◽  
Hepatitis E ◽  
The Novel ◽  
Epidemiological Investigation ◽  
Hepatic Rupture ◽  
Avian Hepatitis E Virus ◽  
Novel Genotype

Hepatic rupture hemorrhage syndrome in chickens caused by a novel genotype avian hepatitis E virus

2018 ◽  
Vol 222 ◽  
pp. 91-97 ◽  
Author(s):  
Qi Su ◽  
Yang Li ◽  
Fanfeng Meng ◽  
Zhizhong Cui ◽  
Shuang Chang ◽  
...  
Keyword(s):  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Hepatic Rupture ◽  
Avian Hepatitis E Virus ◽  
Novel Genotype

Complete genome analysis of avian hepatitis E virus from chicken with hepatic rupture hemorrhage syndrome

2020 ◽  
Vol 242 ◽  
pp. 108577 ◽  
Author(s):  
Qi Su ◽  
Zhihui Zhang ◽  
Yawen Zhang ◽  
Zhizhong Cui ◽  
Shuang Chang ◽  
...  
Keyword(s):  
Genome Analysis ◽  
Complete Genome ◽  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Hepatic Rupture ◽  
Avian Hepatitis E Virus ◽  
Complete Genome Analysis

scholarly journals Putative Novel Genotype of Avian Hepatitis E Virus, Hungary, 2010

2012 ◽  
Vol 18 (8) ◽  
Author(s):  
Krisztián Bányai ◽  
Ádám György Tóth ◽  
Éva Ivanics ◽  
Róbert Glávits ◽  
Katalin Szentpáli-Gavallér ◽  
...  
Keyword(s):  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Avian Hepatitis E Virus ◽  
Novel Genotype

Identification and pathogenicity of a novel genotype avian hepatitis E virus from silkie fowl (gallus gallus)

2020 ◽  
Vol 245 ◽  
pp. 108688
Author(s):  
Baoyuan Liu ◽  
Yiyang Chen ◽  
Liang Zhao ◽  
Meimei Zhang ◽  
Xiaolei Ren ◽  
...  
Keyword(s):  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Gallus Gallus ◽  
Avian Hepatitis E Virus ◽  
Novel Genotype

Infection of Pigs with Avian Hepatitis E Virus (HEV)

2005 ◽  
Author(s):  
C. Kasorndorkbua ◽  
P. J. Thomas ◽  
Patrick G. Halbur ◽  
D. K. Guenette ◽  
F. F. Huang ◽  
...  
Keyword(s):  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Avian Hepatitis E Virus

Identification and characterization of avian hepatitis E virus genotype 2 from chickens with hepatitis-splenomegaly syndrome in Korea

Virus Genes ◽  
2016 ◽  
Vol 52 (5) ◽  
pp. 738-742 ◽  
Author(s):  
Hyun-Woo Moon ◽  
Byung-Woo Lee ◽  
Haan Woo Sung ◽  
Byung-Il Yoon ◽  
Hyuk Moo Kwon
Keyword(s):  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Virus Genotype ◽  
Genotype 2 ◽  
Avian Hepatitis E Virus ◽  
Identification And Characterization

scholarly journals Identification of two neutralization epitopes on the capsid protein of avian hepatitis E virus

2008 ◽  
Vol 89 (2) ◽  
pp. 500-508 ◽  
Author(s):  
E.-M. Zhou ◽  
H. Guo ◽  
F. F. Huang ◽  
Z. F. Sun ◽  
X. J. Meng
Keyword(s):  
Capsid Protein ◽  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Avian Hepatitis E Virus

scholarly journals An Optimized High-Throughput Neutralization Assay for Hepatitis E Virus (HEV) Involving Detection of Secreted Porf2

Viruses ◽  
2019 ◽  
Vol 11 (1) ◽  
pp. 64 ◽  
Author(s):  
Chang Liu ◽  
Wei Cai ◽  
Xin Yin ◽  
Zimin Tang ◽  
Guiping Wen ◽  
...  
Keyword(s):  
High Throughput ◽  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Neutralization Assay ◽  
The Novel ◽  
Specific Antibodies ◽  
Neutralizing Activity ◽  
Elisa Kit ◽  
Neutralizing Capacity ◽  
Potential Threshold

Hepatitis E virus (HEV) is a common cause of acute hepatitis worldwide. Current methods for evaluating the neutralizing activity of HEV-specific antibodies include immunofluorescence focus assays (IFAs) and real-time PCR, which are insensitive and operationally complicated. Here, we developed a high-throughput neutralization assay by measuring secreted pORF2 levels using an HEV antigen enzyme-linked immunosorbent assay (ELISA) kit based on the highly replicating HEV genotype (gt) 3 strain Kernow. We evaluated the neutralizing activity of HEV-specific antibodies and the sera of vaccinated individuals (n = 15) by traditional IFA and the novel assay simultaneously. A linear regression analysis shows that there is a high degree of correlation between the two assays. Furthermore, the anti-HEV IgG levels exhibited moderate correlation with the neutralizing titers of the sera of vaccinated individuals, indicating that immunization with gt 1 can protect against gt 3 Kernow infection. We then determined specificity of the novel assay and the potential threshold of neutralizing capacity using anti-HEV IgG positive sera (n = 27) and anti-HEV IgG negative sera (n = 23). The neutralizing capacity of anti-HEV IgG positive sera was significantly stronger than that of anti-HEV IgG negative. In addition, ROC curve analysis shows that the potential threshold of neutralizing capacity of sera was 8.07, and the sensitivity and specificity of the novel assay was 88.6% and 100%, respectively. Our results suggest that the neutralization assay using the antigen ELISA kit could be a useful tool for HEV clinical research.

Full-length genome of a novel genotype 3 hepatitis E virus strain obtained from domestic pigs in Japan

2017 ◽  
Vol 240 ◽  
pp. 147-153 ◽  
Author(s):  
Putu Prathiwi Primadharsini ◽  
Masao Miyake ◽  
Satoshi Kunita ◽  
Tsutomu Nishizawa ◽  
Masaharu Takahashi ◽  
...  
Keyword(s):  
Virus Strain ◽  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Full Length ◽  
Genotype 3 ◽  
Domestic Pigs ◽  
Novel Genotype ◽  
Full Length Genome
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