HLA‐A, B, C, DRB1 and DQB1 allele and haplotype frequencies in volunteer bone marrow donors from Eastern Region of Saudi Arabia

HLA ◽  
2019 ◽  
Author(s):  
Dunia Jawdat ◽  
Mohsen Al‐Zahrani ◽  
Ahmed Al‐Askar ◽  
Hana Fakhoury ◽  
Fatma Aytül Uyar ◽  
...  
2018 ◽  
Vol 2018 ◽  
pp. 1-8
Author(s):  
Mqondisi Tshabalala ◽  
Charlotte Ingram ◽  
Terry Schlaphoff ◽  
Veronica Borrill ◽  
Alan Christoffels ◽  
...  

Human leukocyte antigen- (HLA-) A, HLA-B, HLA-C, HLA-DRB1, and HLA-DQB1 allele and haplotype frequencies were studied in a subset of 237 volunteer bone marrow donors registered at the South African Bone Marrow Registry (SABMR). Hapl-o-Mat software was used to compute allele and haplotype frequencies from individuals typed at various resolutions, with some alleles in multiple allele code (MAC) format. Four hundred and thirty-eight HLA-A, 235 HLA-B, 234 HLA-DRB1, 41 HLA-DQB1, and 29 HLA-C alleles are reported. The most frequent alleles were A∗02:02g (0.096), B∗07:02g (0.082), C∗07:02g (0.180), DQB1∗06:02 (0.157), and DRB1∗15:01 (0.072). The most common haplotype was A∗03:01g~B∗07:02g~C∗07:02g~DQB1∗06:02~DRB1∗15:01 (0.067), which has also been reported in other populations. Deviations from Hardy-Weinberg equilibrium were observed in A, B, and DRB1 loci, with C~DQB1 being the only locus pair in linkage disequilibrium. This study describes allele and haplotype frequencies from a subset of donors registered at SABMR, the only active bone marrow donor registry in Africa. Although the sample size was small, our results form a key resource for future population studies, disease association studies, and donor recruitment strategies.


2015 ◽  
Vol 10 (2) ◽  
pp. 197-200 ◽  
Author(s):  
Mohammad H. Al-Qahtani ◽  
Abdulelah M. Salih ◽  
Abdullah A. Yousef

2014 ◽  
Vol 75 (3) ◽  
pp. 218-226 ◽  
Author(s):  
Zorana Andric ◽  
Dusan Popadic ◽  
Barbara Jovanovic ◽  
Ivana Jaglicic ◽  
Svetlana Bojic ◽  
...  

2010 ◽  
Vol 30 (6) ◽  
pp. 493-494
Author(s):  
Sourabh Aggarwal ◽  
Vivek Kesar ◽  
Khushbir Singh Bath ◽  
Gurpreet Multani

Author(s):  
Basema Saddik ◽  
Norah Al-Dulaijan

Objectives: Diabetes mellitus is a public health concern worldwide. TeleHealth technology may be an effective tool for empowering patients in the self-management of diabetes mellitus. However despite the great impact of diabetes on healthcare in Saudi Arabia, no research has investigated diabetic patients’ willingness to use this technology. This study investigates diabetic patients’ willingness to use tele-technology as a tool to monitor their disease.Methods:  Data were collected from diabetic patients attending the diabetes education clinic at the Ministry of National Guard Health Affairs (MNGHA) in the Eastern region of Saudi Arabia over a three month period. A survey was developed which measured patients’ willingness to use tele-technology in the self-management of their diabetes as well as their perceived expectations from the technology.Results: The study found that the majority of patients were willing to use tele-technology to self- monitor their diabetes. However, a minority (11.3%) indicated willingness to use the system daily and only half indicated preference to use it once a week (53.8%). Patients who were younger, had higher education levels, were employed, had internet access and had Type II diabetes were significantly more likely to report willingness to use the technology.Conclusions: Diabetic patients could be ready to play a more active role in their care if given the opportunity. Results from this study could serve as a baseline for future studies to develop targeted interventions by trialing tele-technology on a sample of the diabetic population. Patients with diabetes need to be in charge of their own care in order to improve health outcomes across the country. Keywords: diabetes, self-management, tele-technology, willingness.Abbreviations: Ministry of National Guard Health Affairs (MNGHA), Kingdom of Saud Arabia (KSA)


Author(s):  
Abdullah Salem Ahmad Alomari

The present study aimed to reveal the relationship between the quality of space programs watched by children and the social skills of these children،  the study is also trying to identify the relationship between the number of hours watching this space programs and the social skills for these children. The study used a descriptive approach،  the study sample consisted of 215 boys and girls aged between 9- 12 years schools of Al- Dammam in Saudi Arabia،  the researcher used to identify children's programs television watched by children،  where the researcher in this study on the method of analysis of variance One-way Analysis of Variance and Scheffe test for multiple comparisons Multiple Comparison،  which resulted in findings on the lack of social skills for different dimensions: emotional sensitivity،  emotional and adjustment،  and the overall degree of social skills depending on the type of space programs that children watch. In addition to the lack of different social skills for the dimensions: emotional expression،  sensitivity،  emotionality،  and social expression،  and social sensitivity،  and the overall degree of social skills،  while the different settings of emotional and social adjustment depending on the number of hours watching TV channels،  for children who watch satellite channels less.


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