Identification of a novel HLA-C allele,HLA-C*03:313, in a Japanese individual

HLA ◽  
2016 ◽  
Vol 87 (3) ◽  
pp. 186-187 ◽  
Author(s):  
S. Suzuki ◽  
T. Sato ◽  
H. Akatsuka ◽  
M. Kimura ◽  
T. Shiina
Keyword(s):  
Japanese Individual

Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing

2010 ◽  
Vol 42 (11) ◽  
pp. 931-936 ◽  
Author(s):  
Akihiro Fujimoto ◽  
Hidewaki Nakagawa ◽  
Naoya Hosono ◽  
Kaoru Nakano ◽  
Tetsuo Abe ◽  
...  
Keyword(s):  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Massively Parallel Sequencing ◽  
Massively Parallel ◽  
Whole Genome ◽  
Parallel Sequencing ◽  
Variant Analysis ◽  
Japanese Individual

A novelHLA-DQB1*04allele,DQB1*04:10, identified in a Japanese individual

2013 ◽  
Vol 82 (2) ◽  
pp. 148-149 ◽  
Author(s):  
S. Oka ◽  
H. Furukawa ◽  
K. Kashiwase ◽  
N. Tsuchiya ◽  
S. Tohma
Keyword(s):  
Japanese Individual

Identification of the novel HLA‐DQB1 allele, HLA‐DQB1*05:03:01:04 , in a Japanese individual

HLA ◽  
2019 ◽  
Vol 94 (5) ◽  
pp. 466-468 ◽  
Author(s):  
Seik‐Soon Khor ◽  
Yuki Hitomi ◽  
Yosuke Omae ◽  
Yoshimi Ishibashi ◽  
Katsushi Tokunaga
Keyword(s):  
The Novel ◽  
Dqb1 Allele ◽  
Japanese Individual

Detection of the novel HLA‐A allele, HLA‐A*02:01:01:58 , in a Japanese individual

HLA ◽  
2019 ◽  
Vol 94 (5) ◽  
pp. 435-436 ◽  
Author(s):  
Seik‐Soon Khor ◽  
Yuki Hitomi ◽  
Yosuke Omae ◽  
Yoshimi Ishibashi ◽  
Katsushi Tokunaga
Keyword(s):  
The Novel ◽  
Japanese Individual

scholarly journals Japanese Individual Risks of Radon Induced Lung Cancer for Different Exposure Profiles

2005 ◽  
Vol 40 (3) ◽  
pp. 285-294
Author(s):  
Jing CHEN ◽  
Shinji YOSHINAGA ◽  
Shinji TOKONAMI ◽  
Hidenori YONEHARA ◽  
Yuji YAMADA
Keyword(s):  
Lung Cancer ◽  
Japanese Individual

Discovery of the novel HLA‐B allele, HLA‐B*51:01:01:36 in a Japanese individual

HLA ◽  
2019 ◽  
Vol 94 (5) ◽  
pp. 445-447 ◽  
Author(s):  
Seik‐Soon Khor ◽  
Yuki Hitomi ◽  
Yosuke Omae ◽  
Ayumi Ogawa ◽  
Katsushi Tokunaga
Keyword(s):  
The Novel ◽  
Japanese Individual

P5463Hyperfiltration could be a risk factor for development of hypertension: A five-year cohort study

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
M Kuwabara ◽  
K Niwa ◽  
I Hisatome
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Diseases ◽  
Significant Risk ◽  
Regression Analyses ◽  
Chronic Kidney Diseases ◽  
Drinking Habits ◽  
Japanese Individual

Abstract Background Some recent studies showed that hyperfiltration is a risk for cardiovascular disease. However, the mechanism is still unknown. This longitudinal study tested the hypothesis that hyperfiltration could be a risk for hypertension. Methods This study retrospectively included Japanese healthy adults between 30 and 85 years of age who had medical check-up at our Center for Preventive Medicine, both at enrollment (2004) and at 5-year follow-up (2009). We excluded the subjects with hypertension, diabetes mellitus, dyslipidemia, hyperuricemia, or chronic kidney disease (estimated glomerular filtration <60 mL/min/1.73 m2) at the baseline. We divided this study subjects into three categories of eGFR (60–80 (reference), 80–100, and 100≤mL/min/1.73 m2), and defined hyperfiltration as more than 100 mL/min/1.73 m2 of eGFR. We used logistic regression analyses to examine risk factors for development of hypertension with multiple adjustments for age, sex, smoking, drinking habits, body mass index, and eGFR categories. Results In this study, 6045 subjects without comorbidities (mean age of 47±10 years, 1,842 men) were followed for 5 years. Of those, 450 subjects had developed hypertension. After multiple adjustments, hyperfiltration is a risk for development of hypertension (OR: 1.374; 95% confidence incidence (CI), 1.013–1.864), as well as aging (OR: 1.063; 95% CI, 1.052–1.073), higher BMI (OR: 1.244; 95% CI, 1.200–1.289), and drinking habits (OR: 1.387, 95% CI, 1.117–1.721). Conclusion Hyperfiltration carries a significant risk for developing hypertension in Japanese individual without comorbidities. We should take account for hyperfiltration as a risk for hypertension, as well as chronic kidney diseases.

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