scholarly journals Intra- and inter-individual variability in the mechanical properties of the human skin from in vivo measurements on 20 volunteers

2017 ◽  
Vol 23 (4) ◽  
pp. 491-499 ◽  
Author(s):  
E. Jacquet ◽  
J. Chambert ◽  
J. Pauchot ◽  
P. Sandoz
Keyword(s):  
Mechanical Properties ◽  
Human Skin ◽  
Individual Variability ◽  
In Vivo Measurements

Capturing Age-Dependent Properties of Human Skin Using Magnetorheological Elastomers

2018 ◽  
Author(s):  
Kyle Weaver ◽  
Jeong-Hoi Koo ◽  
Tae-Heon Yang ◽  
Young-Min Kim
Keyword(s):  
Mechanical Properties ◽  
Human Skin ◽  
Skin Testing ◽  
Filler Particle ◽  
Variable Stiffness ◽  
Particle Volume ◽  
Magnetorheological Elastomers ◽  
Age Dependent ◽  
Skin Samples

Artificial and synthetic skins are widely used in the medical field; used in applications ranging from skin grafts to suture training pads. There is a growing need for artificial skins with tunable properties. However, current artificial skins do not take into account the variability of mechanical properties between individual humans as well as the age-dependent properties of human skin. Furthermore, there has been little development in artificial skins based on these properties. Thus, the primary purpose of this research is to develop variable stiffness artificial skin samples using magnetorheological elastomers (MREs) whose properties that can be controlled using external magnetic fields. In this study, multiple MRE skin samples were fabricated with varying filler particle volume contents. Using a precision dynamic mechanical analyzer, a series of indenting experiments were performed on the samples to characterize their mechanical properties. The samples were tested using a spherical indenter that indented a total depth of 1 mm with a speed of 0.01 mm/s and unloaded at the same rate. The results show that the modulus or stiffness increases significantly as the iron percent (w/w) in the sample increases. Additionally, the stiffness of the sample increases proportional to the intensity of the applied external magnetic field. To assess the MRE samples’ variability of properties, the testing results were compared with in vivo human skin testing data. The results show the MRE samples are feasible to represent the age-dependent stiffness demonstrated in in vivo human skin testing. The MRE materials studied will be further studied as a variable-stiffness skin model in medical devices, such as radial pulse simulators.

Effects of treatment with prednisolone and PUVA on the mechanical properties of human skin in vivo

1981 ◽  
pp. 31-43
Author(s):  
C. W. Gunner ◽  
E. W. Williams ◽  
M. Greaves ◽  
W. C. Hutton ◽  
T. E. Burlin
Keyword(s):  
Mechanical Properties ◽  
Human Skin

Reliability Investigation of Tissue Resonator Indenter Device

2010 ◽  
Author(s):  
Ming Jia ◽  
Jean W. Zu ◽  
Alireza Hariri
Keyword(s):  
Mechanical Properties ◽  
Soft Tissue ◽  
Soft Tissues ◽  
Tissue Properties ◽  
University Of Toronto ◽  
In Vivo Measurements ◽  
Disease Diagnostics ◽  
Working Principle ◽  
The University

Knowledge of tissue mechanical properties is widely required by medical applications, such as disease diagnostics, surgery operation, simulation, planning, and training. A new portable device, called Tissue Resonator Indenter Device (TRID), has been developed for measurement of regional viscoelastic properties of soft tissues at the Bio-instrument and Biomechanics Lab of the University of Toronto. As a device for soft tissue properties in-vivo measurements, the reliability of TRID is crucial. This paper presents TRID’s working principle and the experimental study of TRID’s reliability with respect to inter-reliability, intra-reliability, and the indenter misalignment effect as well. The experimental results show that TRID is a reliable device for in-vivo measurements of soft tissue mechanical properties.

scholarly journals Critical Factors for In Vivo Measurements of Human Skin by Terahertz Attenuated Total Reflection Spectroscopy

Sensors ◽  
2020 ◽  
Vol 20 (15) ◽  
pp. 4256
Author(s):  
Lixia Wang ◽  
Sayon Guilavogui ◽  
Henghui Yin ◽  
Yiping Wu ◽  
Xiaofei Zang ◽  
...  
Keyword(s):  
Human Skin ◽  
Total Reflection ◽  
Attenuated Total Reflection ◽  
Deep Penetration ◽  
Reference Spectrum ◽  
Critical Factors ◽  
Contact Duration ◽  
In Vivo Measurements ◽  
Different Types

Attenuated total reflection (ATR) geometry is a suitable choice for in vivo measurements of human skin due to the deep penetration of the field into the sample and since it makes it easy to measure the reference spectrum. On the other hand, there are several critical factors that may affect the terahertz (THz) response in these kinds of experiments. Here, we analyse in detail the influence of the following factors: the contact positions between the thumb and the prism, the contact pressure, the contact duration, and the materials of the prism. Furthermore, we use the THz-ATR technology to evaluate different types of handcream and also establish the theoretical model to investigate the reflectivity after interacting with the skin. The results agree well with experimental ones. Our analysis makes it clear the importance of controlling the above factors during measurements to enable reliable THz response and results which, in turn, may be used to monitor water motion in human skin and to predict possible diseases.

New extensometer to measure in vivo uniaxial mechanical properties of human skin

2008 ◽  
Vol 41 (5) ◽  
pp. 931-936 ◽  
Author(s):  
K.H. Lim ◽  
C.M. Chew ◽  
P.C.Y. Chen ◽  
S. Jeyapalina ◽  
H.N. Ho ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Human Skin

The dynamic mechanical properties of human skin in vivo

1983 ◽  
Vol 16 (6) ◽  
pp. 365-372 ◽  
Author(s):  
Russell O. Potts ◽  
Dan A. Chrisman ◽  
Edmund M. Buras
Keyword(s):  
Mechanical Properties ◽  
Human Skin ◽  
Dynamic Mechanical Properties ◽  
Dynamic Mechanical

Quantification of mechanical properties of human skin in vivo

2001 ◽  
Author(s):  
Thorsten Heinrich ◽  
Reinhart A. Lunderstaedt
Keyword(s):  
Mechanical Properties ◽  
Human Skin
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