Evaluation of optical coherence tomography as a non-invasive diagnostic tool in cutaneous wound healing

2013 ◽  
Vol 20 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Monika Kuck ◽  
Helene Strese ◽  
Seyed Arash Alawi ◽  
Martina C. Meinke ◽  
Joachim W. Fluhr ◽  
...  
Keyword(s):  
Wound Healing ◽  
Optical Coherence Tomography ◽  
Diagnostic Tool ◽  
Optical Coherence ◽  
Cutaneous Wound Healing ◽  
Cutaneous Wound ◽  
Non Invasive

scholarly journals Optical coherence tomography angiography monitors human cutaneous wound healing over time

2018 ◽  
Vol 8 (2) ◽  
pp. 135-150 ◽  
Author(s):  
Anthony J. Deegan ◽  
Wendy Wang ◽  
Shaojie Men ◽  
Yuandong Li ◽  
Shaozhen Song ◽  
...  
Keyword(s):  
Wound Healing ◽  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Optical Coherence ◽  
Cutaneous Wound Healing ◽  
Cutaneous Wound ◽  
Over Time

Noninvasive assessment of cutaneous wound healing using ultrahigh-resolution optical coherence tomography

2006 ◽  
Vol 11 (6) ◽  
pp. 064002 ◽  
Author(s):  
Michael J. Cobb ◽  
Yuchuan Chen ◽  
Robert A. Underwood ◽  
Marcia L. Usui ◽  
John Olerud ◽  
...  
Keyword(s):  
Wound Healing ◽  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Cutaneous Wound Healing ◽  
Ultrahigh Resolution ◽  
Cutaneous Wound ◽  
Noninvasive Assessment

scholarly journals Publisher's Note: Noninvasive assessment of cutaneous wound healing using ultrahigh-resolution optical coherence tomography

2006 ◽  
Vol 11 (6) ◽  
pp. 069803 ◽  
Author(s):  
Michael J. Cobb ◽  
Yuchuan Chen ◽  
Robert A. Underwood ◽  
Marcia L. Usui ◽  
John Olerud ◽  
...  
Keyword(s):  
Wound Healing ◽  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Cutaneous Wound Healing ◽  
Ultrahigh Resolution ◽  
Cutaneous Wound ◽  
Noninvasive Assessment

Assessment of cutaneous wound healing using optical coherence tomography

2004 ◽  
Author(s):  
Michael J. Cobb ◽  
Yuchaun Chen ◽  
Robert A. Underwood ◽  
Rahber A. Thariani ◽  
Marcia L. Usui ◽  
...  
Keyword(s):  
Wound Healing ◽  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Cutaneous Wound Healing ◽  
Cutaneous Wound

scholarly journals Comparison between the Effect of Precipitate and Supernatant Aloe vera Gel on Experimental Cutaneous Wound Healing Using Optical Coherence Tomography

2019 ◽  
Vol 11 (2) ◽  
pp. 405-412
Author(s):  
Kusmardi Kusmardi ◽  
Nurrashida Binti Mok Hallim ◽  
Aryo Tedjo ◽  
Anwar Ibrahim ◽  
Salinah Salinah S
Keyword(s):  
Wound Healing ◽  
Optical Coherence Tomography ◽  
Aloe Vera ◽  
Optical Coherence ◽  
Cutaneous Wound Healing ◽  
Cutaneous Wound ◽  
Aloe Vera Gel

Non-invasive assessment of cutaneous wound healing using fluorescent imaging

2014 ◽  
Vol 21 (1) ◽  
pp. 108-113 ◽  
Author(s):  
O. Lee ◽  
J. Kim ◽  
G. Park ◽  
M. Kim ◽  
S. Son ◽  
...  
Keyword(s):  
Wound Healing ◽  
Fluorescent Imaging ◽  
Cutaneous Wound Healing ◽  
Cutaneous Wound ◽  
Non Invasive

scholarly journals Optical Coherence Tomography Reveals Self-Organizing Di-Fork Architecture of Mice Cutaneous Scars

2017 ◽  
Author(s):  
Biswajoy Ghosh ◽  
Mousumi Mandal ◽  
Pabitra Mitra ◽  
Jyotirmoy Chatterjee
Keyword(s):  
Wound Healing ◽  
Optical Coherence Tomography ◽  
Steady State ◽  
Wound Repair ◽  
Stable State ◽  
Tissue Mechanics ◽  
Tissue Loss ◽  
Optical Coherence ◽  
Non Invasive ◽  
Self Organizing

AbstractScientific studies report crucial impacts of biomechanical effectors to modulate wound healing either by scarring or regeneration. Further, the biological decision to predominantly favor the former is still cryptic. Real-time visualization of biomechanical manifestations in situ in scarring is hence necessary. Endorsed by nanostructural testing, synthetic phantom analysis, and computational simulations, we found strong mechanobiological correlates for Swept Source Optical Coherence Tomography (SS-OCT) speckles in mice cutaneous repair (full-thickness) up to 10 months. The theoretical basis of the optomechanics to provide insights into scar form-factor and evolution is proposed. Optomechanical changes have been considered as the resultant of intrinsic (e.g. fiber elastic modulus) and gross tissue mechanics (extracellular matrix (ECM)) in maturing scars. Non-invasive optomechanics supported with microscopic findings reveal scar’s cross-sectional self-organizing di-fork architecture. Dual-compartment heterogeneity of di-fork exhibits stress-evading features with a dichotomy in inhabitant cellular stress-fiber distributions. This differential interactivity of scar with adjoining tissues reflects its architectural intelligence to compensate tissue loss (hypodermis/muscle) by assembling into a di-fork. Gradual establishment of baseline shifted lasting mechanobiological steady-state, later in scarring, expose scar as an alternate stable state within the skin.Significance StatementWound repair in mammals, predominantly culminates into function compromising scar that is occasionally fatal in vital organs. How the biological system often adopts scarring over a restorative regeneration is yet a conundrum. Wound and ambient mechanics play a pivotal role in deciding the healing fate. SS-OCT is hence demonstrated here as a non-invasive window to such mechanical manifestations during skin wound healing. This exposed gradual emergence of temporally maintained and stress-resilient di-fork architecture of the scar with differential neighborhood interfaces. Accommodation of such an alternate self-organizing steady-state of scar sheds light on its sustenance and paradoxical selection.

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