Double counting individuals in meta‐analysis artificially inflates precision. Comment on “Device‐measured light‐intensity physical activity and mortality: A meta‐analysis”

2020 ◽  
Vol 30 (6) ◽  
pp. 1083-1084
Author(s):  
Jakob Tarp ◽  
Knut Eirik Dalene ◽  
Bjørge Herman Hansen ◽  
Jostein Steene‐Johannessen ◽  
Ulf Ekelund
Keyword(s):  
Physical Activity ◽  
Light Intensity ◽  
Meta Analysis ◽  
Double Counting ◽  
Intensity Physical Activity

scholarly journals Device‐measured light‐intensity physical activity and mortality: A meta‐analysis

2019 ◽  
Vol 30 (1) ◽  
pp. 13-24 ◽  
Author(s):  
Po‐Wen Ku ◽  
Mark Hamer ◽  
Yung Liao ◽  
Ming‐Chun Hsueh ◽  
Li‐Jung Chen
Keyword(s):  
Physical Activity ◽  
Light Intensity ◽  
Meta Analysis ◽  
Intensity Physical Activity

Does objectively measured light-intensity physical activity reduce the risk of cardiovascular mortality? A meta-analysis

2020 ◽  
Author(s):  
Shanhu Qiu ◽  
Xue Cai ◽  
Lijing Jia ◽  
Zilin Sun ◽  
Tongzhi Wu ◽  
...  
Keyword(s):  
Physical Activity ◽  
Light Intensity ◽  
Cohort Studies ◽  
Cardiovascular Mortality ◽  
Meta Analysis ◽  
Vigorous Physical Activity ◽  
Physical Activity Guidelines ◽  
Metabolic Equivalents ◽  
Intensity Physical Activity ◽  
Objectively Measured

Abstract Aims Current physical activity guidelines emphasize little on light-intensity physical activity (LPA) in terms of reducing the risk of cardiovascular mortality. This meta-analysis aimed to bridge this gap by assessing their association using objectively measured LPA data. Methods and results Databases of PubMed and Scopus were searched to April 2020 for prospective cohort studies that reported the association of LPA assessed by activity monitors with the risk of cardiovascular mortality in the general population. Multivariable-adjusted hazard ratios (HRs) with 95% confidence intervals (CIs) were pooled using a random-effects model. Dose–response and subgroup analyses were also performed. Six cohort studies with seven datasets enrolling 13 960 participants were included. LPA was all measured by accelerometers. The HR of LPA per 30 min/day for cardiovascular mortality was pooled to be 0.80 (95% CI 0.67–0.96). This association was non-linearly shaped (Pnonlinearity < 0.01) and unaffected by sex difference. Moreover, substituting LPA for sedentary time of 30 min/day lowered the risk of cardiovascular mortality by 16% (95% CI 0.73–0.96). Results showed further that LPA was inferior to moderate-to-vigorous physical activity in reducing the risk of cardiovascular mortality when performed with an equal time-length set at 30 min/day (HR 0.83 vs. 0.54, Pcomparison = 0.046), but became comparable if at an equal activity-amount set at 150 metabolic equivalents-min/day (HR 0.67 vs. 0.54, Pcomparison = 0.41). Conclusion LPA shows potential in reducing the risk of cardiovascular mortality, and interventions targeting at LPA improvement are worth being encouraged.

scholarly journals How does light-intensity physical activity associate with adult cardiometabolic health and mortality? Systematic review with meta-analysis of experimental and observational studies

2018 ◽  
Vol 53 (6) ◽  
pp. 370-376 ◽  
Author(s):  
Sebastien F M Chastin ◽  
Marieke De Craemer ◽  
Katrien De Cocker ◽  
Lauren Powell ◽  
Jelle Van Cauwenberg ◽  
...  
Keyword(s):  
Physical Activity ◽  
Light Intensity ◽  
Observational Studies ◽  
Meta Analysis ◽  
Experimental Studies ◽  
Cardiometabolic Health ◽  
Light Physical Activity ◽  
Intensity Physical Activity ◽  
Light Activity ◽  
The Relationship

AimTo assess the relationship between time spent in light physical activity and cardiometabolic health and mortality in adults.DesignSystematic review and meta-analysis.Data sourcesSearches in Medline, Embase, PsycInfo, CINAHL and three rounds of hand searches.Eligibility criteria for selecting studiesExperimental (including acute mechanistic studies and physical activity intervention programme) and observational studies (excluding case and case–control studies) conducted in adults (aged ≥18 years) published in English before February 2018 and reporting on the relationship between light physical activity (<3 metabolic equivalents) and cardiometabolic health outcomes or all-cause mortality.Study appraisal and synthesisStudy quality appraisal with QUALSYST tool and random effects inverse variance meta-analysis.ResultsSeventy-two studies were eligible including 27 experimental studies (and 45 observational studies). Mechanistic experimental studies showed that short but frequent bouts of light-intensity activity throughout the day reduced postprandial glucose (−17.5%; 95% CI −26.2 to −8.7) and insulin (−25.1%; 95% CI −31.8 to –18.3) levels compared with continuous sitting, but there was very limited evidence for it affecting other cardiometabolic markers. Three light physical activity programme intervention studies (n ranging from 12 to 58) reduced adiposity, improved blood pressure and lipidaemia; the programmes consisted of activity of >150 min/week for at least 12 weeks. Six out of eight prospective observational studies that were entered in the meta-analysis reported that more time spent in daily light activity reduced risk of all-cause mortality (pooled HR 0.71; 95% CI 0.62 to 0.83).ConclusionsLight-intensity physical activity could play a role in improving adult cardiometabolic health and reducing mortality risk. Frequent short bouts of light activity improve glycaemic control. Nevertheless, the modest volume of the prospective epidemiological evidence base and the moderate consistency between observational and laboratory evidence inhibits definitive conclusions.

Duration–Response of Light-Intensity Physical Activity and Glucose Dynamics in Older Adults

2019 ◽  
Vol 16 (1) ◽  
pp. 37-42 ◽  
Author(s):  
Whitney A. Welch ◽  
Scott J. Strath ◽  
Michael Brondino ◽  
Renee Walker ◽  
Ann M. Swartz
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Light Intensity ◽  
Intensity Physical Activity ◽  
Glucose Dynamics

scholarly journals Objective Light-Intensity Physical Activity Associations With Rated Health in Older Adults

2010 ◽  
Vol 172 (10) ◽  
pp. 1155-1165 ◽  
Author(s):  
M. P. Buman ◽  
E. B. Hekler ◽  
W. L. Haskell ◽  
L. Pruitt ◽  
T. L. Conway ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Light Intensity ◽  
Intensity Physical Activity

Sedentarism and light-intensity physical activity (in COPD)

2020 ◽  
pp. 335-345
Author(s):  
Kylie Hill ◽  
Zoe McKeough ◽  
Daniel F. Gucciardi
Keyword(s):  
Physical Activity ◽  
Light Intensity ◽  
Intensity Physical Activity

scholarly journals Association Between Light Intensity Physical Activity And Sedentary Behavior Among Active Older Women

2018 ◽  
Vol 50 (5S) ◽  
pp. 209-210
Author(s):  
Luis Adriano Lima ◽  
Diana Carolina Gonzalez ◽  
João Pedro Silva Junior ◽  
Timóteo Leandro Araujo ◽  
Sandra Mahecha Matsudo ◽  
...  
Keyword(s):  
Physical Activity ◽  
Light Intensity ◽  
Sedentary Behavior ◽  
Older Women ◽  
Intensity Physical Activity
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