Distinct beneficial effects of continuous vs accumulated exercise training on cardiovascular risk factors in Wistar rats

2016 ◽  
Vol 27 (11) ◽  
pp. 1384-1394
Author(s):  
L. V. Costa-Pereira ◽  
D. S. Melo ◽  
C. S. Santos ◽  
B. F. Mendes ◽  
E. A. Esteves ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Exercise Training ◽  
Cardiovascular Risk Factors ◽  
Wistar Rats ◽  
Beneficial Effects

Beneficial effects of rosiglitazone on novel cardiovascular risk factors in patients with Type 2 diabetes mellitus

2008 ◽  
Vol 25 (3) ◽  
pp. 333-340 ◽  
Author(s):  
N. P. E. Kadoglou ◽  
F. Iliadis ◽  
N. Angelopoulou ◽  
D. Perrea ◽  
C. D. Liapis ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Beneficial Effects

scholarly journals Antioxidative Diet Supplementation Reverses High-Fat Diet-Induced Increases of Cardiovascular Risk Factors in Mice

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Hilda Vargas-Robles ◽  
Amelia Rios ◽  
Monica Arellano-Mendoza ◽  
Bruno A. Escalante ◽  
Michael Schnoor
Keyword(s):  
Oxidative Stress ◽  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
High Fat Diet ◽  
Serum Triglyceride ◽  
High Fat ◽  
Daily Consumption ◽  
Beneficial Effects ◽  
Diet Supplementation

Obesity is a worldwide epidemic that is characterized not only by excessive fat deposition but also by systemic microinflammation, high oxidative stress, and increased cardiovascular risk factors. While diets enriched in natural antioxidants showed beneficial effects on oxidative stress, blood pressure, and serum lipid composition, diet supplementation with synthetic antioxidants showed contradictive results. Thus, we tested in C57Bl/6 mice whether a daily dosage of an antioxidative mixture consisting of vitamin C, vitamin E, L-arginine, eicosapentaenoic acid, and docosahexaenoic acid (corabion) would affect cardiovascular risk factors associated with obesity. Obese mice showed increased serum triglyceride and glucose levels and hypertension after eight weeks of being fed a high-fat diet (HFD). Importantly, corabion ameliorated all of these symptoms significantly. Oxidative stress and early signs of systemic microinflammation already developed after two weeks of high-fat diet and were significantly reduced by daily doses of corabion. Of note, the beneficial effects of corabion could not be observed when applying its single antioxidative components suggesting that a combination of various nutrients is required to counteract HFD-induced cardiovascular risk factors. Thus, daily consumption of corabion may be beneficial for the management of obesity-related cardiovascular complications.

scholarly journals Effects of Three Methods of Exercise Training on Cardiovascular Risk Factors in Obese Boys

2017 ◽  
Vol 27 (5) ◽  
Author(s):  
Alireza Ramezani ◽  
Abbas Ali Gaeini ◽  
Morad Hosseini ◽  
Jamshid Mohammadi ◽  
Bahram Mohammadi
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Exercise Training ◽  
Cardiovascular Risk Factors

scholarly journals The counterintuitive role of exercise in the prevention and cause of atrial fibrillation

2020 ◽  
Vol 319 (5) ◽  
pp. H1051-H1058
Author(s):  
Benjamin J. R. Buckley ◽  
Gregory Y. H. Lip ◽  
Dick H. J. Thijssen
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Atrial Fibrillation ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Endurance Exercise ◽  
Premature Mortality ◽  
Beneficial Effects ◽  
Increased Risk

Atrial fibrillation (AF) is the most common cardiac arrhythmia, characterized by irregular atrial activity. AF is related to increased risk of thromboembolic events, heart failure, and premature mortality. Recent advances in our understanding of its pathophysiology include a potentially central role for inflammation and presence of cardiovascular risk factors. The role of physical activity and exercise in the development and progression of AF, however, are not yet fully understood. Physical activity is protective for modifiable cardiovascular risk factors, including those associated with AF. Indeed, emerging research has demonstrated beneficial effects of exercise on AF-specific outcomes, including AF recurrence postablation. Counterintuitively, the prevalence of AF in veteran endurance athletes seems higher compared with the general population. In this review, we discuss the novel evidence and underlying mechanisms underpinning the role of exercise as medicine in the development and management of AF but also the counterintuitive detrimental role of excessive endurance exercise. Finally, we advocate regular (but not long-term high-intensity endurance) exercise training as a safe and effective strategy to reduce the risk of incident AF and to minimize the associated risk of secondary cardiovascular events.

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