scholarly journals An increase in CD62L dim neutrophils precedes the development of pulmonary embolisms in COVID‐19 patients

Author(s):  
Roy Spijkerman ◽  
Nikita K. N. Jorritsma ◽  
Suzanne H. Bongers ◽  
Bas J. J. Bindels ◽  
Bernard N. Jukema ◽  
...  
Keyword(s):  
2008 ◽  
Vol 14 (30) ◽  
pp. 4834 ◽  
Author(s):  
Chang Soo Choi ◽  
Ki Hoon Kim ◽  
Geom Seog Seo ◽  
Eun Young Cho ◽  
Hyo Jeong Oh ◽  
...  

2018 ◽  
Vol 82 (8) ◽  
pp. 2063-2070 ◽  
Author(s):  
Tetsuya Ohira ◽  
Hiroyasu Iso ◽  
Kazumasa Yamagishi ◽  
Akiko Tamakoshi ◽  

1970 ◽  
Vol 6 (1) ◽  
pp. 66-67
Author(s):  
Bikash Dali ◽  
Subarna Acharya ◽  
Sunil C Jha ◽  
Manindra Basnet ◽  
Neelam Pradhan ◽  
...  
Keyword(s):  

DOI: http://dx.doi.org/10.3126/njog.v6i1.5257 NJOG 2011; 6(1): 66-67


Nature ◽  
1965 ◽  
Vol 208 (5013) ◽  
pp. 900-901 ◽  
Author(s):  
HANS SELYE ◽  
BEATRIZ TUCHWEBER ◽  
PAVEL ROHAN
Keyword(s):  

Blood ◽  
2009 ◽  
Vol 114 (22) ◽  
pp. 5056-5056
Author(s):  
Claire Siemes ◽  
Paul Berendes ◽  
Frans van der Straaten ◽  
Ton Cleophas ◽  
Mark-David Levin

Abstract Abstract 5056 OBJECTIVE To investigate the relation between elevated levels of C-reactive protein (CRP) and D-dimer, and to study whether D-dimer levels can be interpreted in relation to elevated levels of CRP in the prediction of a pulmonary embolism in order to increase its specificity without decline in sensitivity. METHODS Between august 2004 and april 2007 (33 months) serum levels of C-reactive protein (mmol/L) and D-dimer (mmol/L) were cross-sectionally collected and pulmonary embolisms on CT-angiograms were scored within 48 hours. The study was devided into three parts. First, characteristics of excluded persons were studied. Second, the correlation between CRP and D-dimer level was considered in those with a defined (i.e. values with < and > symbols excluded) biomarker level. Finally, the effect of CRP level on the sensitivity of D-dimer for pulmonary embolisms was examined. RESULTS CRP and D-dimer levels were positively correlated ( r = 0.37; p < 0.001), and both were increased in persons with a pulmonary embolism (CRP: p = 0.02; D-dimer: p < 0.001). 14 % of variability in D-dimer level was explained by CRP level. Median D-dimer levels were increased in the pulmonary embolism (PE) group, however, the increase in D-dimer level by CRP quartile as was found in the non-PE was not seen in de PE-group. Adding the interaction term of CRP and D-dimer to the statistical model showed some influence on the area under the curve (AUC). Nevertheless, this was not significantly different from the model with only D-dimer levels. However, when stratified for CRP quartile, ROC-curves of the predictive effect of D-dimer on pulmonary embolisms showed a decrease in AUC by increment of CRP quartile. CONCLUSION CRP and D-dimer are positively correlated, and both predictive of PE. The predictive value of D-dimer for PE declines by increment of CRP, although this seems to be safely for a broader range of accompanied CRP levels. Disclosures No relevant conflicts of interest to declare.


2013 ◽  
Vol 35 (2) ◽  
pp. 206-211 ◽  
Author(s):  
Kaisorn L. Chaichana ◽  
Courtney Pendleton ◽  
Christopher Jackson ◽  
Juan Carlos Martinez-Gutierrez ◽  
Andrea Diaz-Stransky ◽  
...  

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