Validation of the functional assessment of anorexia/cachexia therapy instrument to assess quality of life in maintenance hemodialysis patients with cachexia

2022 ◽  
Author(s):  
Zhen Yang ◽  
Yixin Luo ◽  
Haizhen Lu ◽  
Baolin Zou ◽  
Han Wang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Functional Assessment ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Assess Quality ◽  
Maintenance Hemodialysis Patients

Depression and health-related quality of life in maintenance hemodialysis patients

2010 ◽  
Vol 73 (05) ◽  
pp. 374-380 ◽  
Author(s):  
H.C. Park ◽  
H.-B. Yoon ◽  
M.-J. Son ◽  
E.S. Jung ◽  
K.W. Joo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Maintenance Hemodialysis Patients

scholarly journals Effects of l-Carnitine Supplementation in Maintenance Hemodialysis Patients: A Systematic Review

2002 ◽  
Vol 13 (3) ◽  
pp. 708-714
Author(s):  
Jean-Marc Hurot ◽  
Michel Cucherat ◽  
Margaret Haugh ◽  
Denis Fouque
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Exercise Capacity ◽  
Muscle Function ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Serum Triglycerides ◽  
Anemia Management ◽  
Maintenance Hemodialysis Patients

ABSTRACT. There are many causes for carnitine depletion during maintenance hemodialysis. Supplementation with l-carnitine in animals has been associated with improvement in some abnormalities also present in chronic renal failure. However, it is still controversial whether restoring plasma or tissue carnitine will correct clinical or biologic symptoms observed in maintenance hemodialysis. A systematic review is here performed to determine the effects of l-carnitine in maintenance hemodialysis patients. Eighty-three prospective trials were identified from 1978 to 1999 in which l-carnitine was randomly allocated in 21 trials. Change in serum triglycerides, cholesterol fractions, hemoglobin levels, erythropoietin dose, and other symptoms (muscle function, exercise capacity, and quality of life) were examined. A total of 482 patients in 18 trials were considered for analysis. There was no effect of l-carnitine on triglycerides, total cholesterol, or any of its fractions. Before the erythropoietin (EPO) era, l-carnitine treatment was associated with improved hemoglobin (P < 0.01) and with a decreased EPO dose (P < 0.01) and improved resistance to EPO when patients routinely received EPO. Muscle function, exercise capacity, and quality of life could not be reliably assessed because of the noncombinable nature of end points and the limited number of trials. In conclusion, l-carnitine cannot be recommended for treating the dyslipidemia of maintenance hemodialysis patients. By contrast, this review suggests a promising effect of l-carnitine on anemia management. The route of l-carnitine administration should be evaluated because there is no evidence as to the most efficient method of administration in maintenance hemodialysis.

scholarly journals Changes in Quality of Life in Older Hemodialysis Patients: A Cohort Study on Dialysis Outcomes and Practice Patterns

2020 ◽  
Vol 51 (8) ◽  
pp. 650-658
Author(s):  
Ayumi Ishiwatari ◽  
Shungo Yamamoto ◽  
Shingo Fukuma ◽  
Takeshi Hasegawa ◽  
Sachiko Wakai ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Practice Patterns ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Dialysis Vintage ◽  
Health Related Qol ◽  
Health Related ◽  
Dialysis Outcomes ◽  
Maintenance Hemodialysis Patients

Background: Despite improvements in dialysis treatment, mortality rates remain high, especially among older hemodialysis patients. Quality of life (QOL) among hemodialysis patients is strongly associated with higher risk of death. This study aimed to describe the health-related QOL and its change in older maintenance hemodialysis patients and to demonstrate characteristics associated with health-related QOL. Methods: Data on 892 maintenance hemodialysis patients aged 60 years or older who were surveyed using the Kidney Disease Quality of Life Short Form at baseline and 2 years after study enrollment in phases 4 (2009–2011) and 5 (2012–2014) of the Japanese Dialysis Outcomes and Practice Patterns Study were analyzed. We categorized participants into 3 age groups (60–69, 70–79, and ≥80 years) and described baseline physical component summary (PCS) and mental component summary (MCS) scores, as well as their distribution of changes after 2 years across each category. Results: Hemodialysis patients aged 70–79 years and ≥80 years had lower PCS scores than those aged 60–69 years (median: 70–79 years = 43.1; interquartile range [IQR], 35.2–49.4; ≥80 years = 38.8; IQR, 31.6–43.8; 60–69 years = 45.4; IQR, 37.5–51.4; p < 0.001). In contrast, MCS scores did not significantly differ by age category (70–79 years = 45.6; IQR, 38.4–53.7; ≥80 years = 45.4; IQR, 36.9–55.1; 60–69 years = 46.8; IQR, 39.5–55.7; p = 0.1). As dialysis vintage lengthened, the PCS score significantly became lower, whereas no association was found with change in the MCS score. The MCS score declined over time in older patients, especially among those aged 80 years and older after 2 years’ follow-up. Conclusions: Physical QOL became worse as dialysis vintage lengthened. In contrast, mental QOL declined over time within a relatively short period among older maintenance hemodialysis patients.

scholarly journals Validation of the Functional Assessment of Anorexia/Cachexia Therapy Instrument to Assess Quality of Life in Maintenance Hemodialysis-Treated Patients with Cachexia

2020 ◽  
Author(s):  
Yang Zhen ◽  
Huang Yanlin ◽  
Lu Haizhen ◽  
Zhao Ping ◽  
Wang Han ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Functional Assessment ◽  
Discriminant Validity ◽  
Short Form ◽  
Demographic Data ◽  
Reliability And Validity ◽  
Maintenance Hemodialysis ◽  
Good Reliability ◽  
Assess Quality

Abstract Background Cachexia is the ultimate state of many maintenance hemodialysis (MHD)-treated patients. Functional Assessment of Anorexia/Cachexia Therapy (FAACT) is a tool used to evaluate the quality of life of patients with cachexia related to various diseases, but its effectiveness in MHD-treated patients has yet to be verified. This study aims to explore the applicability of FAACT in MHD-treated patients.Methods Qualified MHD-treated patients were selected for FAACT and The Kidney Disease Quality of Life Short Form 36 (KDQOL-36) questionnaire survey, and their demographic data and biochemical test results were collected from electronic medical records. Then, data were analyzed using statistical methods.Results This study enrolled 299 effective patients. The reliability of FAACT and its anorexia-cachexia subscale (ACS) were 0.904 and 0.842, respectively, and their retest exceeded 0.85. A reasonable correlation was found between FAACT and its items, and a reasonable calibration validity was identified between FAACT and KDQOL-36 subscale. FAACT and its subscale ACS showed good discriminant validity in the comparison of patients with different cachexia states and inflammatory states.Conclusions FAACT and ACS have good reliability and validity in MHD-treated patients and are suitable to measure the quality of life of MHD-treated patients with cachexia.

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