The impact of activated protein C resistance on the patency of arteriovenous grafts for hemodialysis access

2021 ◽  
Author(s):  
Stefanie Christine Santler ◽  
Peter Konstantiniuk ◽  
Georg Schramayer ◽  
Florian Prüller ◽  
Gregor Siegl ◽  
...  
Keyword(s):  
Protein C ◽  
Activated Protein C ◽  
Hemodialysis Access ◽  
Activated Protein C Resistance ◽  
Arteriovenous Grafts ◽  
The Impact

Coagulation Factor V Leiden Mutation Was Detected in the Patients with Activated Protein C Resistance in Thailand

1998 ◽  
Vol 80 (08) ◽  
pp. 344-345 ◽  
Author(s):  
Pasra Arnutti ◽  
Motofumi Hiyoshi ◽  
Wichai Prayoonwiwat ◽  
Oytip Nathalang ◽  
Chamaiporn Suwanasophon ◽  
...  
Keyword(s):  
Protein C ◽  
Activated Protein C ◽  
Factor V Leiden ◽  
Coagulation Factor ◽  
Factor V ◽  
Activated Protein C Resistance ◽  
Factor V Leiden Mutation ◽  
Coagulation Factor V

Influence of Plasma Platelets on Activated Protein C Resistance Assay

1995 ◽  
Vol 74 (03) ◽  
pp. 993-994 ◽  
Author(s):  
Johannes Sidelmann ◽  
Jørgen Gram ◽  
Ole Dyg Pedersen ◽  
Jørgen Jespersen
Keyword(s):  
Protein C ◽  
Activated Protein C ◽  
Activated Protein C Resistance

Activated protein C resistance phenotype in patients with antiphospholipid antibodies

1997 ◽  
Vol 130 (2) ◽  
pp. 202-208 ◽  
Author(s):  
Justo Aznar ◽  
Piedad Villa ◽  
Francisco España ◽  
Amparo Estellés ◽  
Salvador Grancha ◽  
...  
Keyword(s):  
Antiphospholipid Antibodies ◽  
Protein C ◽  
Activated Protein C ◽  
Activated Protein C Resistance ◽  
Resistance Phenotype

Activated Protein C Resistance and False Type 2 Protein C Deficiency Detected After Multiple Shunt Failures in a Patient With Hydrocephalus

2001 ◽  
Vol 16 (11) ◽  
pp. 862-863
Author(s):  
Sinan Mahir Kayiran ◽  
Namik Özbek ◽  
Kürsat Tokel ◽  
Sükrü Mercan ◽  
Fusun Alehan
Keyword(s):  
Protein C ◽  
Activated Protein C ◽  
Activated Protein C Resistance ◽  
Protein C Deficiency

The Diagnosis and Clinical Manifestations of Activated Protein C Resistance: A Case Report and Review of the Literature

1996 ◽  
Vol 1 (4) ◽  
pp. 275-280 ◽  
Author(s):  
Howard Daniel Hoerl ◽  
Aldo Tabares ◽  
Kandice Kottke-Marchant
Keyword(s):  
Case Report ◽  
Protein C ◽  
Activated Protein C ◽  
Clinical Manifestations ◽  
Factor V Leiden ◽  
Laboratory Diagnosis ◽  
Factor V ◽  
Review Of The Literature ◽  
Activated Protein C Resistance ◽  
Genetic Anomaly

Activated protein C resistance (APCR) is a recently discovered, medically important cause of venous thrombosis. More than 95% of cases are due to factor V Leiden (FVL), a mutated form of factor V that is resistant to degradation by activated protein C. The prevalence of this disorder, which is inherited in an autosomal dominant fashion, is approximately 5% among asymptomatic people of European heritage. In addition, 20 to 60% of patient cohorts with previous thrombosis demonstrate APCR, making it the most common known genetic cause of abnormal thrombophilia. Current laboratory techniques available for diagnosis include functional assays, such as the APC ratio, as well as DNA-based tests that detect the specific genetic anomaly responsible for FVL. A case report is presented, along with a review of the literature highlighting epidemiology, pathogenesis, clinical features and methods for laboratory diagnosis.

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