The Weather and Quality of Life in ESRD Patients: Everybody Talks About it, But Does Anybody Do Anything About it?

2013 ◽  
Vol 26 (3) ◽  
pp. 260-262 ◽  
Author(s):  
Paul L Kimmel
Keyword(s):  
Quality Of Life ◽  
Esrd Patients

scholarly journals Kidney Transplant in an Old Woman-A Case Report and Review of the Literature

2015 ◽  
Vol 12 (1) ◽  
pp. 62-64
Author(s):  
Lidija Orlic ◽  
Ivana Mikolasevic ◽  
Branka Sladoje-Martinovic ◽  
Ivan Bubic and Sanjin Racki
Keyword(s):  
Quality Of Life ◽  
Renal Transplantation ◽  
Elderly Patients ◽  
End Stage Renal Disease ◽  
Older Patients ◽  
Review Of The Literature ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Abstract The number of elderly patients with chronic kidney disease (CKD) as well as those with end-stage renal disease (ESRD) are increasing worldwide. Renal transplantation is now the treatment of choice for all ESRD patients, including those that are aged 65 or over. Namely, there is a growing evidence that elderly patients, in the absence of contraindications, have better outcomes after renal transplantation than alternative forms of RRT. Although survival, quality of life and economic advantages have been shown after transplantation, renal transplantation is still infrequently offered to older patients. Hereby, we present a case of an old woman who was transplanted in 1994 when “senior” program was still not established and when kidney transplantation at this age was rarity in many countries. She lived 16 years and 8 months with a well-functioning graft and died at the age of 89.

scholarly journals Health-Related Quality of Life in End-Stage Renal Disease Patients: How Often Should We Ask and What Do We Do with the Answer?

2016 ◽  
Vol 41 (1-3) ◽  
pp. 218-224 ◽  
Author(s):  
Shan Shan Chen ◽  
Saleem Al Mawed ◽  
Mark Unruh
Keyword(s):  
Quality Of Life ◽  
Patient Reported Outcomes ◽  
Dialysis Patients ◽  
Patient Reported ◽  
Related Quality ◽  
Health Related ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Background: End-stage renal disease (ESRD) patients have poor health-related quality of life (HRQOL) comparing to general population and comparable HRQOL to patients with other major chronic diseases. Poor HRQOL is associated with shorter survival. There is a limited threshold to which dialysis dose and parameters management can improve HRQOL in ESRD patients. Numerous studies have sought to find interventions to improve HRQOL. This article is to review the symptoms associated with poor HRQOL and how frequent the quality of life (QOL) should be evaluated to improve the outcome. Summary: It is required by the Center for Medicare and Medicaid Services to evaluate HRQOL of dialysis patients annually. KDIGO recommends the symptoms to be assessed regularly and the treatment is redirected toward a patient-centered care model. Studies have shown that measuring patient-reported outcomes frequently, from 4 times a day to every 3-6 months, without intervention did not improve the HRQOL significantly. Appropriate intervention of the symptoms may improve the quality of life (QOL). Studies in oncology have also showed a similar result. The commonly used tools to evaluate the HRQOL in dialysis patients take up to 30 min for completion. Therefore, frequent assessment of all the symptoms can provide more burden than benefit to the patients. In addition to the annual HRQOL measurements, more frequent evaluation of targeted symptoms can be helpful. For appropriate intervention of the symptoms, effective communication between providers, as well as a multidisciplinary approach, is essential to improve HRQOL and outcomes in dialysis patients. Key Messages: Measurement of patient-reported outcomes may provide an opportunity to improve outcomes in ESRD. The frequent measurement of symptoms and QOL may be burdensome. Consider targeted measurement of symptoms to complement HRQOL measurement. Improved communication and the use of a multidisciplinary team provide mechanisms to improve HRQOL in ESRD.

scholarly journals Effects of Oral L-Carnitine Supplementation on Lipid Profile, Anemia, and Quality of Life in Chronic Renal Disease Patients under Hemodialysis: A Randomized, Double-Blinded, Placebo-Controlled Trial

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Afsoon Emami Naini ◽  
Mahnaz Moradi ◽  
Mojgan Mortazavi ◽  
Asghar Amini Harandi ◽  
Mehdi Hadizadeh ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Renal Disease ◽  
Chronic Renal Disease ◽  
Controlled Trial ◽  
The Body ◽  
Maintenance Hemodialysis ◽  
Carnitine Supplementation ◽  
Double Blinded ◽  
Esrd Patients

In patients on maintenance hemodialysis several factors reduce the body stored carnitine which could lead to dyslipidemia, anemia, and general health in these patients. We evaluated the effect of oral L-carnitine supplementation on lipid profiles, anemia, and quality of life (QOL) in hemodialysis patients. In a randomized, double-blinded, placebo-controlled trial, end-stage renal disease (ESRD) patients on hemodialysis received either L-carnitine 1 g/d (n=24) or placebo (27 patients) for 16 weeks. At the end of the study, there was a significant decrease in triglyceride (-31.1±38.7 mg/dL,P=0.001) and a significant increase in HDL (3.7±2.8 mg/dL,P<0.001) levels in the carnitine group. Decrease in total cholesterol (−6.6±16.0 mg/dL,P=0.075) and increase in hemoglobin (0.7±1.7 g/dL,P=0.081) concentrations in the carnitine group were not significant. There was no statistically significant changes in LDL in any group (P>0.05). Erythropoietin dose was significantly decreased in both the carnitine (-4750±5772 mg,P=0.001) and the placebo group (-2000±4296 mg,P<0.05). No improvement was observed in QOL scores of two groups. In ESRD patients under maintenance hemodialysis, oral L-carnitine supplementation may reduce triglyceride and cholesterol and increase HDL and hemoglobin and subsequently reduce needed erythropoietin dose without effect on QOL.

scholarly journals Quality of Life and Depression in Patients With End-stage Renal Disease: a Comparison of Renal Replacement Therapy Modalities

2021 ◽  
Author(s):  
Fei Yang ◽  
Zheng Yang ◽  
Lu Cheng ◽  
Jiayu Tong ◽  
Pusheng Wang
Keyword(s):  
Quality Of Life ◽  
Depressive Symptoms ◽  
Renal Replacement Therapy ◽  
End Stage Renal Disease ◽  
Sf 36 ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients ◽  
Component Scores

Abstract Purpose. Patients with end-stage renal disease (ESRD) face various physical and mental limitations resulting from different renal replacement therapy (RRT) modalities. Renal transplantation (Tx) is considered as the treatment that impacts most on health-related quality of life (HRQOL). This study aimed to analyze and compare the HRQOL and depression levels of patients undergoing hemodialysis (HD), peritoneal dialysis (PD) and Tx.Methods. A single-center cross-sectional sample of 112 HD patients, 68 PD patients and 97 Tx patients participated in our questionnaire survey. The HRQOL and depression levels were assessed through the 36-Item Short-Form Health Survey (SF-36) and Mental Health Inventory (MHI-5), respectively. The multiple linear regression model was performed to examine the factors associated with each of the HRQOL scale scores. Results. The SF-36 HRQOL of Tx patients differed significantly from that in HD and PD groups in all eight dimensions and two components (all P<0.001). More than 45% of patients in each group were facing depressive symptoms. HD patients (63.4%) and PD (67.6%) patients were more depressive compared with Tx patients (45.4%, P =0.006). Depression in ESRD patients contributed to a worse quality of life (P<0.001). Patients ranging in age from 31 to 50, having full-time jobs, receiving Tx and without depression were associated with better HRQOL in the domain of Physical Component Scores (PCS). Patients with unemployment, dismissal or being looking for a job, receiving Tx and without depression were associated with better HRQOL in the domain of Mental Component Scores (MCS).Conclusions. Tx patients had better HRQOL and less depressive symptoms than HD and PD patients. Depression was related to an impaired HRQOL, which was common in ESRD patients. The severity of depression in ESRD patients and the effectiveness of Tx on HRQOL improvement need to be underscored.

scholarly journals Lived Experience of Patients Undergoing Hemodialysis: Quality of Life Perspective

2016 ◽  
Vol 3 (2) ◽  
Author(s):  
Mrs. Rohini. T ◽  
Dr. Punitha. V. Ezhilarasu
Keyword(s):  
Quality Of Life ◽  
Lived Experience ◽  
Structured Interviews ◽  
Van Manen ◽  
Related Quality ◽  
Health Related ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

There is growing recognition of Health-Related Quality of Life (HRQOL) issues in End Stage Renal Disease (ESRD) patients undergoing Hemodialysis (HD). The aim of the present study was to explore the lived experience of Quality of Life (QOL) among patients undergoing Hemodialysis. The study involved a qualitative approach that used an interpretive hermeneutic phenomenology based on Van Manen’s method. The sample included seven patients undergoing Hemodialysis in two selected hospitals at Ernakulam district in Kerala. They were recruited by purposive sampling. Data were collected using semi-structured interviews. The thematic analysis followed the six steps delineated by Max Van Manen and four themes emerged. They were crestfallen life (3 sub themes; hard pressed life, deserted life and abounding losses); support and comfort; accompanying death and unfulfilled wishes. The findings shed light on the lived experience of QOL that has not yet been researched in an Indian scenario. The generated knowledge can be used by health professionals including nurses to help patients undergoing HD lead a life with better quality of life.

scholarly journals TNGKAT DEPRESI DAN KUALITAS HIDUP PASIEN GAGAL GINJAL KRONIK (GGK) BERDASARKAN TINGKATAN USIA DI RSUD dr. H. SOEWONDHO KENDAL

2017 ◽  
Vol 15 (1) ◽  
pp. 39
Author(s):  
Siti Aminah
Keyword(s):  
Quality Of Life ◽  
Young Adulthood ◽  
Negative Correlation ◽  
Quantitative Research ◽  
Esrd Patient ◽  
P Value ◽  
Depression Level ◽  
R Value ◽  
Esrd Patients

Latar Belakang: Berbagai masalah yang menyertai GGK menyebabkan penderitanya frustasi dan depresi. Depresi berpengaruh terhadap kualitas hidup dan harapan hidup pasien GGK. Salah satu faktor yang mempengaruhi tingkat depresi dan kualitas hidup adalah usia. Tujuan: Mengetahui hubungan tingkat depresi dengan kualitas hidup pada pasien gagal ginjal kronis (GGK) di RSUD dr. H. Soewondho Kendal. Metodologi: Penelitian kuantitatif dengan pendekatan korelasi deskriptif  digunakan pada 42 responden pasien GGK yang menjalani hemodialisa di RSUD dr. H. Soewondho Kendal. Hasil: Sebagian besar responden usia dewasa tidak mengalami depresi (57,89%), sedangkan sebagian besar responden usia dewasa muda  (52,17%) mengalami depresi. Responden dewasa muda memiliki kualitas hidup dibawah rata-rata lebih banyak (21,05%) bila dibandingkan dengan responden dewasa (13,63%). Ada hubunganyang negatif  antara tingkat depresi dengan kualitas hidup pasien GGK dengan  r-value = - 0,450 dan p-value 0,000 (p-value < 0,05). Kesimpulan: Ada hubungan yang negatif antara tingkat depresi dengan kualitas hidup pada pasien gagal ginjal kronik (GGK) di RSUD dr. H. Soewondho Kendal. Artinya, semakin depresi seseorang, semakin buruk kualitas hidupnya.Background: End Stage Renal Disease (ESRD) patients encounter many problems that make them frustrated and depressed. Depression is linked with poor quality of life and higher mortality. Age is one of the factors that affect depression and quality of life. Purpose: the aim of this study is to investigate the relationship between depression and quality of life among ESRD patients in dr. H. Soewondho Kendal State Hospital. Methods: quantitative research design with descrptive-correlational aproach was used to investigate the correlation between depression level and quality of life among 42 respondents with ESRD. Results: Most of adulthood is not depressed (57,89%), and most of young adulthood respondents were depressed (52,17%). More young adulthood respondents (21,05%) have poorer quality of life than the adulthood respondents (13,63%). There is a negative correlation between depression level and quality of life among ESRD patient with r-value = -0,450 and p-value 0,000 (p-value <0,05). Conlussion: There is a negative correlation  between depression level and quality of life among ESRD patients, it means, the more depression a person is, the poorer his quality of life is, and the less depression a person is, the better his quality of life.

scholarly journals Health-related quality of life in end-stage renal disease patients, using the Missoula-Vitas quality of life index: a multicenter study

2019 ◽  
Author(s):  
Rositsa Dimova ◽  
Donka Keskinova ◽  
Valeri Tzekov ◽  
Gergana Ginova-Noncheva
Keyword(s):  
Quality Of Life ◽  
Health Related Quality ◽  
Life Index ◽  
Related Quality ◽  
Health Related ◽  
Quality Of Life Index ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Background and aims. Assessment of Health-related Quality of Life in chronic hemodialysis patients (CHD) is a predictive indicator of the outcome of the disease, including mortality and hospitalization. Regular surveys of the quality of life (QoL) in CHD patients have been conducted  worldwide, using various, internationally validated and standardized tools, including the Missoula-VITAS Quality of Life Index scale (MVQOLI). The aim of this study was to examine the reliability and validity of the Bulgarian version of the Missoula-VITAS Quality of Life Index-15 (B-MVQOLI-15) and QoL in CHD patients using this instrument. Methods. Our study was designed as multi-center cross-sectional. It incorporated 263 end-stage renal disease (ESRD) patients on CHD from across the country and applied the B-MVQOLI-15. Internal consistency and convergent validity of the index were assessed. Non-parametric methods were used to evaluate  the impact of demographic factors on the different dimensions scores and on the total score. The relationship between the total QoL score, the total MVQOLI-15 score and dimensions scores were measured based on Spearman's rho Correlation Coefficient. Results. The total MVQOLI-15 score in the study was 16.44, which is slightly above the middle of the index scale. The patients with higher education were less satisfied with the level of their symptom control compared to patients with lower education. However, high education patients seem to manage better with everyday life compared to those with low education. Men seem to feel more satisfied  than women when fulfilling their daily activities (Р=0.026). Retired patients and unemployed expressed more satisfaction, compared to the employed (P=0.021). Also, patients on dialysis for over 5 years had lower QoL scores (Р=0.043). Conclusions. B-MVQOLI-15 is a reliable instrument to measure QoL in Bulgarian patients with CHD. The majority of CHD patients rate their QoL as “Fair“. Four of all five dimensions positively affect the QoL of CHD patients. The most important dimensions positively affecting the QoL of CHD patients were: interpersonal relationships and transcendent factors. Future studies are necessary to assess the adequacy of the delivered dialysis, the level of medico-social care and the needs of ESRD patients treated with CHD in order to improve their QoL.

Impact of socioeconomic status on the quality of life of ESRD patients

2003 ◽  
Vol 41 (1) ◽  
pp. 186-195 ◽  
Author(s):  
Ricardo Sesso ◽  
João F. Rodrigues-Neto ◽  
Marcos B. Ferraz
Keyword(s):  
Quality Of Life ◽  
Socioeconomic Status ◽  
Esrd Patients

scholarly journals P0944UREMIC SARCOPENIA IN THE ELDER: PRELIMINARY RESULTS OF A PRECISION MEDICINE APPROACH IN A COHORT OF UREMIC PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Rocco Baccaro ◽  
Wanda Lattanzi ◽  
Francesca Maria D'Ascenzo ◽  
Patrizia Silvestri ◽  
Giovanni Gambaro ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Muscle Strength ◽  
Diagnostic Criteria ◽  
Muscle Mass ◽  
Gait Speed ◽  
Daily Activity ◽  
Handgrip Strength ◽  
Uremic Patients ◽  
Esrd Patients

Abstract Background and Aims Sarcopenia is defined as a chronic condition of “muscle failure”, characterized by reduced muscular strength, mass and performance. End-stage renal disease (ESRD) and sarcopenia have several complications in common including inflammation, low sexual hormones, reduced levels of Vitamin D, and low satellite cells proliferation rate. Sarcopenic and uremic patients have higher risk for fracture, cardiovascular events, cognitive impairment, low quality of life, hospitalization and death. The European Working Group on Sarcopenia in Older People (EWGSOP2) 2019 guidelines standardize the diagnostic criteria and recommend a systematic approach for sarcopenia assessment. The aim of our study is to evaluate the prevalence of sarcopenia in ESRD patients not yet on dialysis and to characterize their clinical, laboratory and behavioral features. Method This is a pilot cross-sectional study. ESRD patients expected to initiate replacement therapy (hemodialysis or peritoneal dialysis), age ≥60 years, free mobility and hemoglobin levels ≥9.5 g/dL were enrolled. Exclusion criteria were: use of steroids &gt;3 months during the previous year, previous renal replacement treatments. Enrolled patients were screened for sarcopenia following the three diagnostic criteria: muscle strength (through “handgrip strength” and “chair stand-up test”), muscle mass (with dual X-ray absorptiometry and bio-electrical impedance analysis), and muscle performance (with “4m gait speed test”). Clinical data were collected as well as anthropometric measures. Patients also underwent an abdominal ultrasound and a hematology, chemistry, urinary and inflammation laboratory panel. Finally, they filled questionnaires for sarcopenia identification (SARC-F), quality of life (SF-36), daily activity (ADL and iADL) and nutritional status. GFR was estimated according to CKD-EPI formula. Results We evaluated 9 patients (2 females and 7 males), mean age 72 ± 7 years, mean GFR 10.2±1.5 mL/min/1.73 m2 (range 7.3, 11.8). 7/9 reported hypertension history, 4/9 were diabetic. The prevalence of sarcopenia was 44% (4 patients) according EWGSOP2 criteria. Table 1 reports diagnostic exam results from our cohort. Taking individually EGWSOP2 criteria 4 patients showed low muscle strength, 5 reached the threshold for a low DXA muscle mass while 3 patients had a low gait speed performance, marker for sarcopenia severity. Compared with controls, sarcopenic patients (Table 2) showed a significantly lower handgrip strength (15.0±4.3 vs 23.0±6.7 Kg respectively, p-value 0.03), a lower but not significant appendicular lean mass (ALM) index normalized for squared height (European criteria) or for BMI (American criteria). Moreover, sarcopenic patients were more anemic (p 0.05), with a lower hematocrit (p 0.04). Finally, SF36 questionnaire describes sarcopenic patients as more jaded about physical activity, with impaired social activity and higher bodily pain. Conclusion Sarcopenia has a complex and diversified background, and ESRD represents an important risk factor. Sarcopenic patients with ESRD might need more carefulness on daily activity, anemia management, physical functioning and muscle recovery.

scholarly journals Health related quality of life among haemodialysis and kidney transplant recipients from Nepal: a cross sectional study using WHOQOL-BREF

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Kamal Ranabhat ◽  
Pratik Khanal ◽  
Shiva Raj Mishra ◽  
Anu Khanal ◽  
Sangita Tripathi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Economic Status ◽  
Educational Status ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Maintenance Haemodialysis ◽  
Related Quality ◽  
Esrd Patients

Abstract Background Very less is known about health-related quality of life (HRQOL) among patients with kidney diseases in Nepal. This study examined HRQOL among haemodialysis and kidney transplant recipients in Nepal. Methods The Nepali version of World Health Organization Quality of Life Instruments -(WHOQOL-BREF) questionnaire was administered using face to face interviews among end stage renal disease (ESRD) patients, from two large national referral centers in Nepal. The differences in socio-demographic characteristics among ESRD patients were examined using the Chi-square test. The group differences in quality of life (QOL) were examined using the Mann-Whitney U test and Kruskal-Wallis tests. Results Of the 161 participants, 92 (57.1%) were renal transplant recipients and 69 (42.9%) patients were on maintenance haemodialysis. Hypertension (70.9%) was the most common co-morbidity among ESRD patients. Haemodialysis patients scored significantly lower than the transplant recipients in all four domains as well as in overall perception of quality of life and general health. Ethnicity (p = 0.020), socio-economic status (p < 0.001), educational status (p < 0.001) and employment status (p = 0.009) were significantly associated with the overall QOL in ESRD patients. Across patient groups, educational status (p = 0.012) was positively associated with QOL in dialysis patients, while urban residence (p = 0.023), higher socio-economic status (p < 0.001), higher educational status (p = 0.004) and diabetes status (p = 0.010) were significantly associated with better QOL in transplant recipients. Conclusion The overall QOL of the renal transplant recipients was higher than that of the patients on maintenance haemodialysis; this was true in all four domains of the WHOQOL-BREF. ESRD patients with low HRQOL could benefit from targeted risk modification intervention.

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