Synthetic microdata for establishment surveys under informative sampling

2020 ◽  
Author(s):  
Hang J. Kim ◽  
Jörg Drechsler ◽  
Katherine J. Thompson
Keyword(s):  
Informative Sampling

On-Line Coordination Tasks for Multi-robot Systems Using Adaptive Informative Sampling

2020 ◽  
pp. 318-327
Author(s):  
Carlos Nieto-Granda ◽  
John G. Rogers III ◽  
Nicholas Fung ◽  
Stephanie Kemna ◽  
Henrik I. Christensen ◽  
...  
Keyword(s):  
Robot Systems ◽  
On Line ◽  
Informative Sampling ◽  
Multi Robot

SamWalker: Social Recommendation with Informative Sampling Strategy

2019 ◽  
Author(s):  
Jiawei Chen ◽  
Can Wang ◽  
Sheng Zhou ◽  
Qihao Shi ◽  
Yan Feng ◽  
...  
Keyword(s):  
Sampling Strategy ◽  
Social Recommendation ◽  
Informative Sampling

scholarly journals Population Pharmacokinetics of Conventional and Intermittent Dosing of Liposomal Amphotericin B in Adults: a First Critical Step for Rational Design of Innovative Regimens

2012 ◽  
Vol 56 (10) ◽  
pp. 5303-5308 ◽  
Author(s):  
William W. Hope ◽  
Joanne Goodwin ◽  
Timothy W. Felton ◽  
Michael Ellis ◽  
David A. Stevens
Keyword(s):  
Monte Carlo ◽  
Optimal Design ◽  
Monte Carlo Simulations ◽  
Amphotericin B ◽  
Liposomal Amphotericin ◽  
Liposomal Amphotericin B ◽  
High Dose ◽  
Pharmacokinetic Data ◽  
Informative Sampling ◽  
Sampling Times

ABSTRACTThere is increased interest in intermittent regimen of liposomal amphotericin B, which may facilitate use in ambulatory settings. Little is known, however, about the most appropriate dosage and schedule of administration. Plasma pharmacokinetic data were acquired from 30 patients receiving liposomal amphotericin B for empirical treatment of suspected invasive fungal infection. Two cohorts were studied. The first cohort received 3 mg of liposomal amphotericin B/kg of body weight/day; the second cohort received 10 mg of liposomal amphotericin B/kg at time zero, followed by 5 mg/kg at 48 and 120 h. The levels of liposomal amphotericin B were measured by high-pressure liquid chromatography (HPLC). The pharmacokinetics were estimated by using a population methodology. Monte Carlo simulations were performed. D-optimal design was used to identify maximally informative sampling times for both conventional and intermittent regimens for future studies. A three-compartment pharmacokinetic model best described the data. The pharmacokinetics for both conventional and intermittent dosing were linear. The estimates for the mean (standard deviation) for clearance and the volume of the central compartment were 1.60 (0.85) liter/h and 20.61 (15.27) liters, respectively. Monte Carlo simulations demonstrated considerable variability in drug exposure. Bayesian estimates for clearance and volume increased in a linear manner with weight, but only the former was statistically significant (P= 0.039). D-optimal design provided maximally informative sampling times for future pharmacokinetic studies. The pharmacokinetics of a conventional and an intermittently administered high-dose regimen liposomal amphotericin B are linear. Further pharmacokinetic-pharmacodynamic preclinical and clinical studies are required to identify safe and effective intermittent regimens.

scholarly journals Bayesian Estimation Under Informative Sampling with Unattenuated Dependence

2020 ◽  
Vol 15 (1) ◽  
pp. 57-77
Author(s):  
Matthew R. Williams ◽  
Terrance D. Savitsky
Keyword(s):  
Bayesian Estimation ◽  
Informative Sampling
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