scholarly journals Quantal Risk Assessment Database: A Database for Exploring Patterns in Quantal Dose-Response Data in Risk Assessment and its Application to Develop Priors for Bayesian Dose-Response Analysis

Risk Analysis ◽  
2018 ◽  
Vol 39 (3) ◽  
pp. 616-629 ◽  
Author(s):  
Matthew W. Wheeler ◽  
Walter W. Piegorsch ◽  
Albert John Bailer
Keyword(s):  
Risk Assessment ◽  
Dose Response ◽  
Response Analysis ◽  
Response Data

Commentary: EPA's proposed expansion of dose-response analysis is a positive step towards improving its ecological risk assessment

2019 ◽  
Vol 246 ◽  
pp. 566-570 ◽  
Author(s):  
Evgenios Agathokleous ◽  
Alessandro Anav ◽  
Valda Araminiene ◽  
Alessandra De Marco ◽  
Marisa Domingos ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Ecological Risk ◽  
Ecological Risk Assessment ◽  
Dose Response ◽  
Response Analysis ◽  
Positive Step

Framework for Identification and Collection of Data Useful for Risk Assessments of Microbial Foodborne or Waterborne Hazards: A Report from the International Life Sciences Institute Research Foundation Advisory Committee on Data Collection for Microbial Risk Assessment

2007 ◽  
Vol 70 (7) ◽  
pp. 1744-1751 ◽  
Author(s):  
ISABEL WALLS
Keyword(s):  
Risk Assessment ◽  
Decision Making ◽  
Risk Management ◽  
Data Collection ◽  
Dose Response ◽  
Management Decision ◽  
Microbial Risk Assessment ◽  
Microbial Risk ◽  
Response Data ◽  
Management Decision Making

A microbial risk assessment (MRA) can provide the scientific basis for risk management decision making. Much data are needed to complete an MRA, including quantitative data for pathogens in foods. The purpose of this document was to provide information on data needs and data collection approaches for MRAs that will be useful for national governments, particularly in developing countries. A framework was developed, which included the following activities: (i) identify the purpose of data collection—this should include stating the specific question(s) to be addressed; (ii) identify and gather existing data—this should include a determination of whether the data are sufficient to answer questions to be addressed; (iii) develop and implement a data collection strategy; (iv) analyze data and draw conclusions; and (v) use data to answer questions identified at the start of the process. The key data needs identified for an MRA were as follows: (i) burden of foodborne or waterborne disease; (ii) microbial contamination of foods; and (iii) consumption patterns. In addition, dose-response data may be necessary, if existing dose-response data cannot be used to estimate dose response for the population of interest. Data should be collected with a view to its use in risk management decision making. Standard sampling and analysis methods should be used to ensure representative samples are tested, and care should be taken to avoid bias when selecting data sets. A number of barriers to data collection were identified, including a lack of clear understanding of the type of data needed to undertake an MRA, which is addressed in this document.

scholarly journals Using sparse dose-response data for wildlife risk assessment

2013 ◽  
Vol 10 (1) ◽  
pp. 3-11 ◽  
Author(s):  
Ryan A Hill ◽  
Brian J Pyper ◽  
Gary S Lawrence ◽  
Gary S Mann ◽  
Patrick Allard ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Dose Response ◽  
Response Data

A database designed to support dose-response analysis and risk assessment

Toxicology ◽  
1996 ◽  
Vol 114 (1) ◽  
pp. 81-90 ◽  
Author(s):  
Daniel J. Guth ◽  
T.Slater Raymond
Keyword(s):  
Risk Assessment ◽  
Dose Response ◽  
Response Analysis

Analysis of Transcriptomic Dose-Response Data for Toxicology and Risk Assessment

2011 ◽  
pp. 237-250 ◽  
Author(s):  
Russell S. Thomas ◽  
Longlong Yang ◽  
Harvey J. Clewell ◽  
Melvin E. Andersen
Keyword(s):  
Risk Assessment ◽  
Dose Response ◽  
Response Data
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