scholarly journals P10‐4: Clinical study about the safety of orexin receptor antagonist suvorexant for severe sleep apnea syndrome

Respirology ◽  
2021 ◽  
Vol 26 (S3) ◽  
pp. 398-398
Keyword(s):  
Clinical Study ◽  
Sleep Apnea ◽  
Receptor Antagonist ◽  
Sleep Apnea Syndrome ◽  
Apnea Syndrome ◽  
Severe Sleep Apnea

Study on the frequency and risk factors of moderate-to-severe sleep apnea syndrome in rheumatoid arthritis

2016 ◽  
Vol 26 (5) ◽  
pp. 681-684 ◽  
Author(s):  
Tomoyuki Mutoh ◽  
Yasuaki Okuda ◽  
Sho Mokuda ◽  
Naoya Sawada ◽  
Kenichiro Matoba ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Risk Factors ◽  
Sleep Apnea ◽  
Sleep Apnea Syndrome ◽  
Apnea Syndrome ◽  
Severe Sleep Apnea

scholarly journals Gender differences in obstructive sleep apnea syndrome: a clinical study of 1166 patients

2004 ◽  
Vol 98 (10) ◽  
pp. 984-989 ◽  
Author(s):  
Esther Quintana-Gallego ◽  
Carmen Carmona-Bernal ◽  
Francisco Capote ◽  
Ángeles Sánchez-Armengol ◽  
Georgina Botebol-Benhamou ◽  
...  
Keyword(s):  
Gender Differences ◽  
Obstructive Sleep Apnea ◽  
Clinical Study ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Obstructive Sleep ◽  
Apnea Syndrome

scholarly journals P300 abnormalities in patients with severe sleep apnea syndrome

2001 ◽  
Vol 55 (3) ◽  
pp. 247-248 ◽  
Author(s):  
Yuichi Inoue ◽  
Kazuyoshi Nanba ◽  
Kazushige Kojima ◽  
Hideaki Mitani ◽  
And Heii Arai
Keyword(s):  
Sleep Apnea ◽  
Sleep Apnea Syndrome ◽  
Apnea Syndrome ◽  
Severe Sleep Apnea

scholarly journals Emotional Stress Evaluation of Patients with Moderate and Severe Sleep Apnea Syndrome

2016 ◽  
Vol 21 (01) ◽  
pp. 28-32 ◽  
Author(s):  
Micheli Santos ◽  
Tatiana Nakano ◽  
Felipe Mendes ◽  
Bruno Duarte ◽  
Silvio Marone
Keyword(s):  
Sleep Apnea ◽  
Emotional Stress ◽  
Sleep Apnea Syndrome ◽  
Stress Evaluation ◽  
Apnea Syndrome ◽  
Severe Sleep Apnea

scholarly journals Benefit of Atrial Overdrive Pacing in Patients with Sleep Apnea: A Meta-Analysis

2021 ◽  
Vol 10 (18) ◽  
pp. 4065
Author(s):  
Nithi Tokavanich ◽  
Pattranee Leelapatana ◽  
Somchai Prechawat ◽  
Voravut Rungpradubvong ◽  
Wimwipa Mongkonsritrakoon ◽  
...  
Keyword(s):  
Sleep Apnea ◽  
Sleep Apnea Syndrome ◽  
Mean Difference ◽  
Apnea Hypopnea Index ◽  
Standard Mean Difference ◽  
Significant Difference ◽  
Overdrive Pacing ◽  
Apnea Syndrome ◽  
The Impact ◽  
Severe Sleep Apnea

Background: Sleep apnea is one of the most common conditions around the world. This disorder can significantly impact cardiovascular morbidity and mortality. Atrial overdrive pacing (AOP) is a treatment modality that can potentially decrease respiratory events. There is currently a lack of evidence to confirm the benefits of AOP. We aimed to assess the impact of AOP in patients with obstructive sleep apnea (OSA), central sleep apnea (CSA), and mixed type. Methods: A literature search for studies that reported the impact on apnea–hypopnea index (AHI) by cardiac implantable electronic devices with different pacing modes was conducted using MEDLINE, Embase, and Cochrane Database from inception through July 2020. Pooled standard mean difference with 95%CI was calculated using a random-effects model. Results: Fifteen studies, including thirteen randomized studies and two observational studies containing 440 patients, were identified. The standard mean difference in apnea–hypopnea index of atrial overdrive pacing demonstrated less duration of apnea/hypopnea in patients with atrial overdrive pacing (AOP) (SMD −0.29, 95%CI: −0.48, −0.10, I2 = 57%). Additional analysis was performed to assess the effect of atrial overdrive pacing in patients with or without severe sleep apnea syndrome (mean AHI < 30 defined as non-severe). There was no statistically significant difference in standardized mean in AHI in both subgroups between AOP and control groups (SMD −0.25, severe sleep apnea syndrome SMD −0.03, I2 = 0.00%). Conclusions: AOP was associated with a statistically significant reduction in AHI, but the magnitude of reduction was small. AOP may potentially be used as an adjunctive treatment with other modalities in treating patients with sleep apnea.

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