scholarly journals P8‐166: A case of meningeal carcinomatosis due to small cell lung cancer triggered by Cauda Equina syndrome

Respirology ◽  
2021 ◽  
Vol 26 (S3) ◽  
pp. 353-353
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Cauda Equina Syndrome ◽  
Cauda Equina ◽  
Small Cell ◽  
Meningeal Carcinomatosis ◽  
Small Cell Lung

Teniposide for meningeal carcinomatosis of small cell lung cancer

Lung Cancer ◽  
1993 ◽  
Vol 10 (3-4) ◽  
pp. 247-249 ◽  
Author(s):  
Winette T.A. van der Graaf ◽  
Hanny Haaxma-Reiche ◽  
Jos Th.M. Burghouts ◽  
Pieter E. Postmus
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Meningeal Carcinomatosis ◽  
Small Cell Lung

Sudden blindness and deafness disclosing meningeal carcinomatosis in non-small cell lung cancer

2018 ◽  
Vol 119 (3) ◽  
pp. 491-492
Author(s):  
Guillaume Costentin ◽  
C. Richard ◽  
A. Rouille ◽  
B. Bourre ◽  
R. Lefaucheur ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Meningeal Carcinomatosis ◽  
Small Cell Lung ◽  
Sudden Blindness

Cerebrospinal fluid bombesin and calcitonin in patients with central nervous system metastases from small-cell lung cancer.

1986 ◽  
Vol 4 (11) ◽  
pp. 1620-1627 ◽  
Author(s):  
A G Pedersen ◽  
K L Becker ◽  
F Bach ◽  
R H Snider ◽  
A F Gazdar ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Clinical Importance ◽  
Small Cell ◽  
Meningeal Carcinomatosis ◽  
Small Cell Lung ◽  
Cns Involvement ◽  
Cns Metastases ◽  
Diagnostic Measures

To determine whether levels of mammalian bombesin (MB) or calcitonin would be useful in detecting CNS metastases in patients with small-cell lung cancer (SCLC), we measured their concentrations in the CSF of 94 patients who underwent lumbar puncture for suspected CNS involvement. The MB concentration was significantly elevated in the 51 patients with definite CNS metastases as compared with the 30 patients without apparent CNS involvement (P less than .01). This significance was due to increased levels of MB in 18 patients with meningeal carcinomatosis. Whereas CSF MB was detectable (greater than 10 fmol/mL) in only 7% of patients without apparent CNS involvement, CSF MB was detectable in 21% with parenchymal CNS metastases and in 78% of those with meningeal carcinomatosis. Interestingly, 93% of patients having MB concentrations above 20 fmol/mL had meningeal metastases. The calcitonin concentration was significantly elevated in 42 patients with CNS metastases as compared with 27 patients without CNS involvement (P less than .01). Both the 15 patients with meningeal carcinomatosis and the 27 patients with only parenchymal metastases had significantly elevated levels of CSF calcitonin as compared with those without CNS metastases. Fifty-three percent of patients with meningeal carcinomatosis and 48% with parenchymal metastases had a CSF calcitonin level above 18 fmol/mL, whereas only 7% without apparent CNS metastases exceeded this level. Sixty-seven percent of all patients with CNS metastases had increased CSF levels of one of the two hormonal markers. Thus, in SCLC patients, an elevated CSF calcitonin strongly suggested CNS metastases and an elevated MB was very suggestive of the presence of meningeal carcinomatosis. However, only the latter observation seems of clinical importance due to the difficulties in establishing this diagnosis with current diagnostic measures.

scholarly journals Successful treatment with lorlatinib in a patient with meningeal carcinomatosis of ALK-positive non-small cell lung cancer resistant to alectinib and brigatinib

Medicine ◽  
2021 ◽  
Vol 100 (39) ◽  
pp. e27385
Author(s):  
Koki Nakashima ◽  
Yoshiki Demura ◽  
Kosuke Kurokawa ◽  
Toshihiro Takeda ◽  
Norihiro Jikuya ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Successful Treatment ◽  
Small Cell ◽  
Meningeal Carcinomatosis ◽  
Small Cell Lung ◽  
Alk Positive
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