scholarly journals P8‐50: Lung cancer, as a risk factor for abdominal aortic aneurysm (AAA)

Respirology ◽  
2021 ◽  
Vol 26 (S3) ◽  
pp. 306-307
2019 ◽  
Vol 25 (18) ◽  
pp. 2033-2037 ◽  
Author(s):  
Djordje Radak ◽  
Slobodan Tanaskovic ◽  
Mihailo Neskovic

: The rising pandemic of obesity in modern society should direct attention to a more comprehensive approach to abdominal aortic aneurysm (AAA) treatment in the affected population. Although overweight patients are considered prone to increased surgical risk, studies on the subject did not confirm or specify the risks well enough. : Associated comorbidities inevitably lead to a selection bias leaning towards endovascular abdominal aortic repair (EVAR), as a less invasive treatment option, which makes it hard to single out obesity as an independent risk factor. The increased technical difficulty often results in prolonged procedure times and increased blood loss. Several smaller studies and two analyses of national registries, including 7935 patients, highlighted the advantages of EVAR over open repair (OR) of abdominal aortic aneurysm, especially in morbidly obese population (relative risk reduction up to 47%). On the other hand, two other studies with 1374 patients combined, concluded that EVAR might not have an advantage over OR in obese patients (P = 0.52). Obesity is an established risk factor for wound infection after both EVAR and OR, which is associated with longer length of stay, subsequent major operations, and a higher rate of graft failure. Percutaneous EVAR technique could present a promising solution to reducing this complication. : EVAR seems like a more feasible treatment option than OR for obese patients with AAA, due to lower overall morbidity and mortality rates, as well as reduced wound-related complication rates. However, there is a clear lack of high-quality evidence on the subject, thus future prospective trials are needed to confirm this advantage.


2012 ◽  
Vol 76 (6) ◽  
pp. 1380-1384 ◽  
Author(s):  
Kota Yamamoto ◽  
Toshihiro Fukui ◽  
Shigefumi Matsuyama ◽  
Minoru Tabata ◽  
Haruo Aramoto ◽  
...  

2007 ◽  
Vol 9 (2) ◽  
pp. 166-172 ◽  
Author(s):  
P. Neary ◽  
C. Hurson ◽  
D. O. Briain ◽  
A. Brabazon ◽  
D. Mehigan ◽  
...  

1995 ◽  
Vol 9 (2) ◽  
pp. 199-204
Author(s):  
Satoshi Sakai ◽  
Kiyokage Kubo ◽  
Hirotoku Arakawa ◽  
Shigeyuki Fuwa ◽  
Koji Matsumoto ◽  
...  

Author(s):  
Emma Altobelli ◽  
Leonardo Rapacchietta ◽  
Valerio Profeta ◽  
Roberto Fagnano

Abdominal aortic aneurysm (AAA) represents an important public health problem with a prevalence between 1.3% and 12.5%. Several population-based randomized trials have evaluated ultrasound screening for AAA providing evidence of a reduction in aneurysm-related mortality in the screened population. The aim of our study was to perform a systematic review and meta-analysis of the risk factors for AAA. We conducted a systematic review of observational studies and we performed a meta-analysis that evaluated the following risk factors: gender, smoking habits, hypertension, coronary artery disease and family history of AAA. Respect to a previous a meta-analysis we added the funnel plot to examine the effect sizes estimated from individual studies as measure of their precision; sensitivity analysis to check the stability of study findings and estimate how the overall effect size would be modified by removal of one study; cumulative analysis to evaluate the trend between studies in relation to publication year. Abdominal aortic aneurysm prevalence is higher in smokers and in males. On the other hand, while diabetes is a risk factor for many cardiovascular diseases, it is not a risk factor for AAA. In addition, it is important to underline that all countries, where AAA screening was set up, had high income level and the majority belong to Western Europe (United Kingdom, Sweden, Italy, Poland, Spain and Belgium). Abdominal aortic aneurysm screening is fundamental for public health. It could avoid deaths, ruptures, and emergency surgical interventions if abdominal aortic aneurysm was diagnosed early in the population target for screening.


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