In vivo probe‐based confocal laser endomicroscopy in chronic interstitial lung diseases: Specific descriptors and correlation with chest CT

Respirology ◽  
2019 ◽  
Vol 24 (8) ◽  
pp. 783-791 ◽  
Author(s):  
Mathieu Salaün ◽  
Florian Guisier ◽  
Stéphane Dominique ◽  
Anne Genevois ◽  
Vincent Jounieaux ◽  
...  
Keyword(s):  
Lung Diseases ◽  
Interstitial Lung Diseases ◽  
Chest Ct ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser

scholarly journals In vivo endomicroscopic features of distal airways in chronic bronchitis and chronic obstructive pulmonary disease

2018 ◽  
Vol 9 (4) ◽  
pp. 15-24
Author(s):  
O. V. Danilevskaya ◽  
A. V. Averyanov
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Chronic Bronchitis ◽  
Pulmonary Disease ◽  
Lung Diseases ◽  
Diagnostic Methods ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease

Relevance: Probe-based confocal laser endomicroscopy (CLE) of distal airways is a unique technology that allows real-time visualization of structures containing natural fluorophores, which are emitted by exposure to laser radiation with a wavelength of 488 nm, in vivo. To date, the endomicroscopic features of the distal respiratory tract have not been adequately studied in lung diseases, including chronic obstructive pulmonary disease and chronic bronchitis. The goal of the present study is to describe the endomicroscopic signs of the distal parts of the respiratory system in chronic inflammatory lung diseases such as chronic obstructive pulmonary disease and chronic bronchitis. Methods: A total of 21 patients with emphysematous and bronchitic phenotypes of chronic obstructive pulmonary disease and chronic bronchitis were examined. All the patients have undergone CLE of distal airways or alveoloscopy during bronchoscopy. The most pathognomonic changes were evaluated on the obtained endomicroscopic images. Results: For each studied nosological form of chronic inflammatory lung diseases, by careful morphometric analysis of a significant number of informative images, the most specific endomicroscopic changes were identified with the release of CLE patterns. Conclusions: CLE of distal airways in patients with chronic inflammatory lung diseases allows visualizing changes in the elastic framework of the acini, as well as identifying pathological intraluminal contents, which can be attributed to valuable additional tools in a row of diagnostic methods of respiratory medicine.

Imaging pattern in interstitial lung diseases using probe based confocal laser endomicroscopy (pCLE)

2015 ◽  
Author(s):  
Edith Silbernagel ◽  
Wolfgang Gesierich ◽  
Michael Lindner ◽  
Alicia Morresi-Hauff ◽  
Juergen Behr ◽  
...  
Keyword(s):  
Lung Diseases ◽  
Interstitial Lung Diseases ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser

Probe-based confocal laser endomicroscopy in differential diagnosis of interstitial lung diseases

2018 ◽  
Author(s):  
Igor Mamenko ◽  
Igor Vasilev ◽  
Irina Tabanakova ◽  
Roman Velshikaev ◽  
Sultan Gasanmagomedov ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Lung Diseases ◽  
Interstitial Lung Diseases ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser

Utility of Probe-Based Confocal Laser Endomicroscopy to Aid With and Improve Safety of Transbronchial Cryobiopsy for Diffuse Interstitial Lung Diseases

CHEST Journal ◽  
2017 ◽  
Vol 152 (4) ◽  
pp. A888
Author(s):  
Kovid Trivedi ◽  
Paras Patel ◽  
Ashley Ferraro ◽  
Satish Kalanjeri ◽  
Adam Wellikoff ◽  
...  
Keyword(s):  
Lung Diseases ◽  
Interstitial Lung Diseases ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser

Visualization of brain microvasculature and blood flow in vivo: Feasibility study using confocal laser endomicroscopy

2021 ◽  
Author(s):  
Evgenii Belykh ◽  
Xiaochun Zhao ◽  
Brandon Ngo ◽  
Dara S. Farhadi ◽  
Adam Kindelin ◽  
...  
Keyword(s):  
Blood Flow ◽  
Feasibility Study ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser ◽  
Brain Microvasculature

S1426: High-Definition In-Vivo Probe-Based Confocal Laser Endomicroscopy of the Common Bile Duct

2010 ◽  
Vol 71 (5) ◽  
pp. AB158-AB159 ◽  
Author(s):  
Frederick K. Shieh ◽  
Michael H. Nathanson ◽  
Hillary Drumm ◽  
Priya A. Jamidar
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser ◽  
High Definition ◽  
The Common

scholarly journals Endomicroscopy and Cancer: A New Approach to the Visualization of Neoangiogenesis

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Renato Cannizzaro ◽  
Maurizio Mongiat ◽  
Vincenzo Canzonieri ◽  
Mara Fornasarig ◽  
Stefania Maiero ◽  
...  
Keyword(s):  
Cancer Progression ◽  
Confocal Laser Endomicroscopy ◽  
Molecular Profile ◽  
Confocal Laser ◽  
Antiangiogenic Treatment ◽  
New Approach ◽  
Angiogenic Therapy ◽  
Imaging Tool ◽  
Subcellular Resolution

Probe-based Confocal Laser Endomicroscopy (pCLE) is a novel imaging technique for gastrointestinal endoscopy providingin vivomicroscopy at subcellular resolution. It offers the possibility to analyze neoangiogenesis and vessel densityin vivo. Angiogenetic switch is essential in cancer progression. Aim of the paper was to review the use of this imaging tool to analyze colorectal and gastric cancers vascularizationin vivo. The aim is to provide the possibility of combining diagnostic evidences with vascularization and molecular profile to evaluate the efficacy of an antiangiogenic treatment in association with conventional therapy. pCLE can be considered a revolutionary method for real-time assessment of changes in vascularization pattern in this tumors and it may open the possibility to address the use of anti-angiogenic therapy in order to improve the outcome of the treatment.

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