Rapid versus gradual lung function decline in bronchiolitis obliterans syndrome after haematopoietic stem cell transplantation is associated with survival outcome

Respirology ◽  
2019 ◽  
Vol 24 (5) ◽  
pp. 459-466 ◽  
Author(s):  
Wang‐Chun Kwok ◽  
Bin‐Miao Liang ◽  
Macy M.S. Lui ◽  
Terence C.C. Tam ◽  
Joycelyn P.Y. Sim ◽  
...  
Keyword(s):  
Stem Cell ◽  
Lung Function ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Bronchiolitis Obliterans ◽  
Haematopoietic Stem Cell Transplantation ◽  
Bronchiolitis Obliterans Syndrome ◽  
Survival Outcome ◽  
Haematopoietic Stem Cell ◽  
Lung Function Decline

scholarly journals Restrictive chronic lung function decline after haematopoietic stem cell transplantation

2015 ◽  
Vol 47 (1) ◽  
pp. 336-339 ◽  
Author(s):  
Ji-Young Yang ◽  
Sang Young Oh ◽  
Jin Woo Song ◽  
Tae Sun Shim ◽  
Sei Won Lee ◽  
...  
Keyword(s):  
Stem Cell ◽  
Lung Function ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Haematopoietic Stem Cell Transplantation ◽  
Haematopoietic Stem Cell ◽  
Lung Function Decline

scholarly journals Noninfectious pulmonary complications of haematopoietic stem cell transplantation

2020 ◽  
Vol 29 (156) ◽  
pp. 190119
Author(s):  
Samran Haider ◽  
Navin Durairajan ◽  
Ayman O. Soubani
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Haematopoietic Stem Cell Transplantation ◽  
Infectious Complications ◽  
Bronchiolitis Obliterans Syndrome ◽  
Pulmonary Complications ◽  
Morbidity And Mortality ◽  
Haematopoietic Stem Cell ◽  
High Morbidity

Haematopoietic stem cell transplantation (HSCT) is an established treatment for a variety of malignant and nonmalignant conditions. Pulmonary complications, both infectious and noninfectious, are a major cause of morbidity and mortality in patients who undergo HSCT. Recent advances in prophylaxis and treatment of infectious complications has increased the significance of noninfectious pulmonary conditions. Acute lung injury associated with idiopathic pneumonia syndrome remains a major acute complication with high morbidity and mortality. On the other hand, bronchiolitis obliterans syndrome is the most challenging chronic pulmonary complication facing clinicians who are taking care of allogeneic HSCT recipients. Other noninfectious pulmonary complications following HSCT are less frequent. This review provides a clinical update of the incidence, risk factors, pathogenesis, clinical characteristics and management of the main noninfectious pulmonary complications following HSCT.

scholarly journals Successful bilateral lung transplantation and simultaneous Nuss technique correction of pectus excavatum post-allogeneic haematopoietic stem cell transplantation

2019 ◽  
Author(s):  
Zhenrong Zhang ◽  
Hao Ding ◽  
Feng Liu ◽  
Jingyu Chen
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Lung Transplantation ◽  
Bronchiolitis Obliterans ◽  
Haematopoietic Stem Cell Transplantation ◽  
Pectus Excavatum ◽  
Bronchiolitis Obliterans Syndrome ◽  
Haematopoietic Stem Cell ◽  
Bilateral Lung Transplantation ◽  
Bilateral Lung

Abstract Bronchiolitis obliterans syndrome after allogeneic haematopoietic stem cell transplantation has aroused clinical concern. We describe a case of a 39-year-old female patient diagnosed as bronchiolitis obliterans syndrome and concomitant pectus excavatum with a Haller index of 3.32. The patient received bilateral lung transplantation and simultaneously underwent Nuss surgery via bilateral anterolateral thoracotomies with veno-arterial extracorporeal membrane oxygenation support. The bar was removed 2 years after transplantation, and the patient has been stable in the past 4 years with haematological remission and satisfactory lung function.

Sign in / Sign up

Export Citation Format

Share Document