scholarly journals High‐pressure non‐invasive ventilation during exercise in COPD patients with chronic hypercapnic respiratory failure: A randomized, controlled, cross‐over trial

Respirology ◽  
2018 ◽  
Vol 24 (3) ◽  
pp. 254-261 ◽  
Author(s):  
Rainer Gloeckl ◽  
Vasileios Andrianopoulos ◽  
Antje Stegemann ◽  
Julian Oversohl ◽  
Tessa Schneeberger ◽  
...  
Keyword(s):  
High Pressure ◽  
Respiratory Failure ◽  
Invasive Ventilation ◽  
Hypercapnic Respiratory Failure ◽  
Non Invasive ◽  
Randomized Controlled ◽  
Copd Patients ◽  
Non Invasive Ventilation

scholarly journals European Respiratory Society guidelines on long-term home non-invasive ventilation for management of COPD

2019 ◽  
Vol 54 (3) ◽  
pp. 1901003 ◽  
Author(s):  
Begum Ergan ◽  
Simon Oczkowski ◽  
Bram Rochwerg ◽  
Annalisa Carlucci ◽  
Michelle Chatwin ◽  
...  
Keyword(s):  
Health Outcome ◽  
Respiratory Failure ◽  
Task Force ◽  
Invasive Ventilation ◽  
European Respiratory Society ◽  
Hypercapnic Respiratory Failure ◽  
Non Invasive ◽  
Copd Patients ◽  
Non Invasive Ventilation

BackgroundWhile the role of acute non-invasive ventilation (NIV) has been shown to improve outcome in acute life-threatening hypercapnic respiratory failure in COPD, the evidence of clinical efficacy of long-term home NIV (LTH-NIV) for management of COPD is less. This document provides evidence-based recommendations for the clinical application of LTH-NIV in chronic hypercapnic COPD patients.Materials and methodsThe European Respiratory Society task force committee was composed of clinicians, methodologists and experts in the field of LTH-NIV. The committee developed recommendations based on the GRADE (Grading, Recommendation, Assessment, Development and Evaluation) methodology. The GRADE Evidence to Decision framework was used to formulate recommendations. A number of topics were addressed under a narrative format which provides a useful context for clinicians and patients.ResultsThe task force committee delivered conditional recommendations for four actionable PICO (target population-intervention-comparator-outcome) questions, 1) suggesting for the use of LTH-NIV in stable hypercapnic COPD; 2) suggesting for the use of LTH-NIV in COPD patients following a COPD exacerbation requiring acute NIV 3) suggesting for the use of NIV settings targeting a reduction in carbon dioxide and 4) suggesting for using fixed pressure support as first choice ventilator mode.ConclusionsManaging hypercapnia may be an important intervention for improving the health outcome of COPD patients with chronic respiratory failure. The task force conditionally supports the application of LTH-NIV to improve health outcome by targeting a reduction in carbon dioxide in COPD patients with persistent hypercapnic respiratory failure. These recommendations should be applied in clinical practice by practitioners that routinely care for chronic hypercapnic COPD patients.

Sign in / Sign up

Export Citation Format

Share Document