scholarly journals Late-onset noninfectious interstitial lung disease following autologous haematopoietic stem cell transplantation in paediatric patients

Respirology ◽  
2016 ◽  
Vol 21 (6) ◽  
pp. 1068-1074 ◽  
Author(s):  
Yoon-Kyoung Lee ◽  
Rimm Huh ◽  
Jihyun Kim ◽  
Kangmo Ahn ◽  
Ki Woong Sung ◽  
...  
Keyword(s):  
Stem Cell ◽  
Interstitial Lung Disease ◽  
Stem Cell Transplantation ◽  
Lung Disease ◽  
Cell Transplantation ◽  
Haematopoietic Stem Cell Transplantation ◽  
Late Onset ◽  
Haematopoietic Stem Cell ◽  
Paediatric Patients

scholarly journals Noninfectious lung complications after allogeneic haematopoietic stem cell transplantation

2018 ◽  
Vol 51 (5) ◽  
pp. 1702617 ◽  
Author(s):  
Anne Bergeron ◽  
Sylvie Chevret ◽  
Régis Peffault de Latour ◽  
Karine Chagnon ◽  
Constance de Margerie-Mellon ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Haematopoietic Stem Cell Transplantation ◽  
Late Onset ◽  
Cox Model ◽  
University Teaching ◽  
Haematopoietic Stem Cell ◽  
Close Monitoring ◽  
History Of

Epidemiological data on late-onset noninfectious pulmonary complications (LONIPCs) following allogeneic haematopoietic stem cell transplantation (HSCT) are derived exclusively from retrospective studies and are conflicting. We aimed to evaluate prospectively the incidence, risk factors and outcomes for LONIPCs.All consecutive patients scheduled to receive allogeneic HSCT between 2006 and 2008 at a university teaching hospital in France were screened for inclusion in the study. Eligible patients were those surviving at day 100. Among 243 screened patients, 198 patients were included in the analysis. The median (interquartile range) follow-up was 72.3 (15.2–88.5) months. 55 LONIPCs were diagnosed in 43 patients. Bronchiolitis obliterans syndrome (n=22) and interstitial lung disease (n=12) were the most common LONIPCs. At 36 months after inclusion, the estimated cumulative incidence of LONIPCs was 19.8% (95% CI 14.2–25.3%). The estimated median survival after the diagnosis of LONIPCs was 78.5 months (95% CI 20.0–not reached). Based on a multivariate Cox model, a history of chest irradiation anytime prior to HSCT, a history of pneumonia within 100 days post-HSCT and a low mean forced expiratory flow at 25–75% of forced vital capacity at day 100 were associated with the development of LONIPCs.Our data provide clues to identify patients at high risk of developing LONIPCs. These patients should be targeted for close monitoring to provide earlier LONIPC treatment or prophylactic treatment.

Treatment of hepatitis C in two paediatric patients using sofosbuvir during haematopoietic stem cell transplantation

2019 ◽  
Vol 24 (8) ◽  
pp. 603-607
Author(s):  
Antonio G Grasso ◽  
Aurelio Sonzogni ◽  
Davide Zanon ◽  
Alessandra Maestro ◽  
Stefano Loiacono ◽  
...  
Keyword(s):  
Stem Cell ◽  
Hepatitis C ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Haematopoietic Stem Cell Transplantation ◽  
Haematopoietic Stem Cell ◽  
Paediatric Patients

scholarly journals TCR Α+ Β+/CD19+ Cell Depleted Haematopoietic Stem Cell Transplantation for Paediatric Patients

2018 ◽  
Vol 24 (3) ◽  
pp. S435
Author(s):  
Richard Mitchell ◽  
Theresa Cole ◽  
Peter J. Shaw ◽  
Francoise Mechinaud ◽  
Tracey A. O'Brien ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Haematopoietic Stem Cell Transplantation ◽  
Haematopoietic Stem Cell ◽  
Paediatric Patients

scholarly journals Late-onset noninfectious interstitial lung disease after allogeneic hematopoietic stem cell transplantation

2014 ◽  
Vol 108 (10) ◽  
pp. 1525-1533 ◽  
Author(s):  
Frédéric Schlemmer ◽  
Sylvie Chevret ◽  
Gwenaël Lorillon ◽  
Cédric De Bazelaire ◽  
Régis Peffault de Latour ◽  
...  
Keyword(s):  
Stem Cell ◽  
Interstitial Lung Disease ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Lung Disease ◽  
Cell Transplantation ◽  
Hematopoietic Stem Cell ◽  
Late Onset ◽  
Hematopoietic Stem

Immunity after (re)vaccination of paediatric patients following haematopoietic stem cell transplantation

2012 ◽  
Vol 101 (8) ◽  
pp. e373-e377 ◽  
Author(s):  
Helena Olkinuora ◽  
Helena Käyhty ◽  
Irja Davidkin ◽  
Merja Roivainen ◽  
Rose-Marie Ölander ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Haematopoietic Stem Cell Transplantation ◽  
Haematopoietic Stem Cell ◽  
Paediatric Patients
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