Melatonin can improve viability and functional integrity of cooled and frozen/thawed rabbit spermatozoa

2020 ◽  
Author(s):  
Aya M. Fadl ◽  
Abdel Raouf M. Ghallab ◽  
Mostafa M. Abou‐Ahmed ◽  
Adel R. Moawad
Keyword(s):  
Functional Integrity ◽  
Rabbit Spermatozoa

MODERNISM AND THE PROBLEM OF CROSS-CULTURAL COMMUNICATION

2020 ◽  
Vol 25 (2) ◽  
pp. 75-80
Author(s):  
Irina Stanislavova ◽  
Galina Solovyova
Keyword(s):  
Cross Cultural ◽  
Cultural Communication ◽  
Cultural System ◽  
Cross Cultural Communication ◽  
Functional Integrity

The article is devoted to the study of issues related to the problem of “intercultural com-munication”.The complexity and relevance of this problem for the modern stage of cultur-al development is shown. Modernism is seen as an element of erosion of the functional integrity and balance of the dominant cultural system. Based on this research, a number of conclusions are made.

Testing of Functional Integrity of p53 Protein in Primary Breast Cancer by a Rapid Quantitative p53-p21WAF1 Double Assay May Improve the Clinical Value of p53

Tumor Biology ◽  
2006 ◽  
Vol 27 (5) ◽  
pp. 252-260
Author(s):  
Gregor Westhof ◽  
Michael Olbrecht ◽  
Manfred Wolff ◽  
Sven Schiermeier ◽  
Ralf C. Zimmermann ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Primary Breast Cancer ◽  
P53 Protein ◽  
Clinical Value ◽  
Functional Integrity

scholarly journals Excision and transposition of Tn5 as an SOS activity in Escherichia coli.

Genetics ◽  
1991 ◽  
Vol 128 (1) ◽  
pp. 45-57 ◽  
Author(s):  
C T Kuan ◽  
S K Liu ◽  
I Tessman
Keyword(s):  
Escherichia Coli ◽  
Binding Site ◽  
Reca Protein ◽  
Precursor Molecule ◽  
Functional Integrity ◽  
Lexa Protein ◽  
Lexa Binding ◽  
Additional Role ◽  
Stimulation Of

Abstract Excision and transposition of the Tn5 element in Escherichia coli ordinarily appear to occur by recA-independent mechanisms. However, recA(Prtc) genes, which encode RecA proteins that are constitutively activated to the protease state, greatly enhanced excision and transposition; both events appeared to occur concomitantly and without destruction of the donor DNA. The recombinase function of the RecA protein was not required. Transposition was accompanied by partial, and occasionally full, restoration of the functional integrity of the gene vacated by the excised Tn5. The stimulation of transposition was inhibited by an uncleavable LexA protein and was strongly enhanced by an additional role of the RecA(Prtc) protein besides its mediation of LexA cleavage. To account for the enhanced transposition, we suggest that (i) there may be a LexA binding site within the promoter for the IS50 transposase, (ii) activated RecA may cleave the IS50 transposition inhibitor, and (iii) the transposase may be formed by RecA cleavage of a precursor molecule.

scholarly journals Intraoperative monitoring for tethered cord surgery: an update

2004 ◽  
Vol 16 (2) ◽  
pp. E8 ◽  
Author(s):  
Karl F. Kothbauer ◽  
Klaus Novak
Keyword(s):  
Electrical Stimulation ◽  
Anal Sphincter ◽  
External Anal Sphincter ◽  
Continuous Monitoring ◽  
Pudendal Nerve ◽  
Tethered Cord ◽  
Sensory Pathways ◽  
Functional Integrity ◽  
Muscle Responses ◽  
Stimulation Of

Object Intraoperative neurophysiological recording techniques have found increasing use in neurosurgical practice. The development of new recording techniques feasible while the patient receives a general anesthetic have improved their practical use in a similar way to the use of digital recording, documentation, and video technology. This review intends to provide an update on the techniques used and their validity. Methods Two principal methods are used for intraoperative neurophysiological testing during tethered cord release. Mapping identifies functional neural structures, namely nerve roots, and monitoring provides continuous information on the functional integrity of motor and sensory pathways as well as reflex circuitry. Mapping is performed mostly by using direct electrical stimulation of a structure within the surgical field and recording at a distant site, usually a muscle. Sensory mapping can also be performed with peripheral stimulation and recording within the surgical site. Monitoring of the motor system is achieved with motor evoked potentials. These are evoked by transcranial electrical stimulation and recorded from limb muscles and the external anal sphincter. The presence or absence of muscle responses are the parameters monitored. Sensory potentials evoked by tibial or pudendal nerve stimulation and recorded from the dorsal columns via an epidurally inserted electrode and/or from the scalp as cortical responses are used to access the integrity of sensory pathways. Amplitudes and latencies of these responses are then interpreted. The bulbocavernosus reflex, with stimulation of the pudendal nerve and recording of muscle responses in the external anal sphincter, is used for continuous monitoring of the reflex circuitry. Presence or absence of this response is the pertinent parameter that is monitored. Conclusions Intraoperative neurophysiology provides a wide and reliable set of techniques for intraoperative identification of neural structures and continuous monitoring of their functional integrity.

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