scholarly journals Toward a neurobehavioral trait conceptualization of depression proneness

2019 ◽  
Vol 56 (7) ◽  
pp. e13367 ◽  
Author(s):  
Colin B. Bowyer ◽  
Keanan J. Joyner ◽  
James R. Yancey ◽  
Noah C. Venables ◽  
Greg Hajcak ◽  
...  
Keyword(s):  
Depression Proneness

scholarly journals Stress vulnerability promotes an alcohol prone phenotype in a preclinical model of sustained depression

2018 ◽  
Author(s):  
Danai Riga ◽  
Leanne JM Schmitz ◽  
Yvar van Mourik ◽  
Witte JG Hoogendijk ◽  
Taco J De Vries ◽  
...  
Keyword(s):  
Social Defeat ◽  
Preclinical Model ◽  
Self Administration ◽  
Depression Vulnerability ◽  
Stress Vulnerability ◽  
The Social ◽  
Depression Proneness ◽  
Male Wistar Rats ◽  
Alcohol Seeking

AbstractMajor depression and alcohol-related disorders frequently co-occur. Depression severity weighs on the magnitude and persistence of comorbid alcohol use disorder (AUD), with severe implications for disease prognosis. Here, we investigated whether depression vulnerability drives propensity to AUD at the preclinical level. We used the social defeat-induced persistent stress (SDPS) model of chronic depression in combination with operant alcohol self-administration (SA). Male Wistar rats were subjected to social defeat (5 episodes) and prolonged social isolation (~12 weeks) and subsequently classified as SDPS-prone or SDPS-resilient based on their affective and cognitive performance. Using an operant alcohol SA paradigm, acquisition, motivation, extinction and cue-induced reinstatement of alcohol-seeking were examined in the two subpopulations. SDPS-prone animals showed increased alcohol SA, excessive motivation to acquire alcohol, persistent alcohol-seeking despite alcohol unavailability, extinction resistance and increased cue-induced relapse; the latter could be blocked by the α2 adrenoreceptor agonist guanfacine. In SDPS-resilient rats, prior exposure to social defeat increased alcohol SA without affecting any other measures of alcohol-seeking and -taking. Our data revealed that depression proneness confers vulnerability to alcohol, emulating patterns of alcohol dependence seen in human addicts, and that depression resilience to a large extent protects from the development of AUD-like phenotypes. Furthermore, our data suggest that stress exposure alone, independently of depressive symptoms, alters alcohol intake in the long-term.

The depression proneness rating scale: Reliability, validity, and factor structure

1990 ◽  
Vol 9 (3) ◽  
pp. 255-263 ◽  
Author(s):  
Robert Zemore ◽  
Donald G. Fischer ◽  
Laura S. Garratt ◽  
Colleen Miller
Keyword(s):  
Factor Structure ◽  
Rating Scale ◽  
Scale Reliability ◽  
Depression Proneness

Development of a Self-Report Measure of Depression-Proneness

1983 ◽  
Vol 52 (1) ◽  
pp. 211-216 ◽  
Author(s):  
Robert Zemore
Keyword(s):  
Psychometric Properties ◽  
Discriminant Validity ◽  
Female Students ◽  
Self Report ◽  
Wide Range ◽  
Self Reports ◽  
Depression Proneness ◽  
Severity Of Depression ◽  
Alternative Approaches ◽  
Report Measure

Two retrospective self-report measures of depression-proneness were constructed and their psychometric properties investigated. A sample of 75 female students, selected to provide a wide range of depression-proneness scores, completed the two depression-proneness self-reports along with a measure of current severity of depression. A second session (retest) was conducted 4 mo. later. Subjects were then rated for degree of depression-proneness by two or more close friends and family members. Test-retest and coefficient alpha estimates of reliability were sufficiently high to recommend both depression-proneness measures as research instruments. Both self-report measures correlated significantly; rs = .38 and .41 with friends' and families' ratings of depression-proneness, which provides evidence for the validity of the depression-proneness measures. Little or no evidence was found for the discriminant validity of these measures. The advantages of retrospective self-reports over alternative approaches for identifying depression-prone individuals are discussed.

Depression proneness in treatment-seeking smokers: a taxometric analysis

2004 ◽  
Vol 36 (5) ◽  
pp. 1155-1170 ◽  
Author(s):  
David R Strong ◽  
Richard A Brown ◽  
Christopher W Kahler ◽  
Elizabeth E Lloyd-Richardson ◽  
Raymond Niaura
Keyword(s):  
Treatment Seeking ◽  
Taxometric Analysis ◽  
Depression Proneness

scholarly journals Nicotine dependence, PTSD symptoms, and depression proneness among male and female smokers

2006 ◽  
Vol 31 (2) ◽  
pp. 223-231 ◽  
Author(s):  
Frances P. Thorndike ◽  
Rachel Wernicke ◽  
Michelle Y. Pearlman ◽  
David A.F. Haaga
Keyword(s):  
Nicotine Dependence ◽  
Ptsd Symptoms ◽  
Male And Female ◽  
Depression Proneness

Factor Structure of the Depression-Proneness Rating Scale

1987 ◽  
Vol 61 (3) ◽  
pp. 863-866
Author(s):  
Sung-Mook Hong
Keyword(s):  
University Students ◽  
Principal Components Analysis ◽  
Factor Structure ◽  
Principal Components ◽  
Rating Scale ◽  
Varimax Rotation ◽  
Cognitive Components ◽  
Depression Proneness ◽  
Components Analysis ◽  
Depression Scales

The Zemore Depression-Proneness Rating Scale was administered to 208 university students. A principal components analysis with varimax rotation identified three factors representing Negative Self-attitude, Performance Difficulty, and Lack of Appetite. Some similarity between the present factors and those of the Beck Depression Inventory was discussed. Because the scale overemphasizes cognitive components, attention to items on the somatic aspects of depression was suggested. However, it should be noted that depression-proneness appears to be the feature of Zemore's scale that sets it apart from other depression scales.

Prediction of Depression-Proneness

1988 ◽  
Vol 62 (1) ◽  
pp. 122-122 ◽  
Author(s):  
Sung-Mook Hong ◽  
Jennifer Mayo
Keyword(s):  
Depression Proneness
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