Evaluating depression in cognitively healthy elderly people by using Mini‐Mental State Examination

2019 ◽  
Vol 20 (1) ◽  
pp. 96-103
Author(s):  
Norio Murayama ◽  
Kazumi Ota ◽  
Yusuke Matsunaga ◽  
Kanako Ichikura ◽  
Yuko Fukase ◽  
...  
Keyword(s):  
Elderly People ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Healthy Elderly ◽  
State Examination ◽  
Healthy Elderly People

scholarly journals Oxytocin and elderly MRI-based hippocampus and amygdala volume: a 7-year follow-up study

2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Ryuzo Orihashi ◽  
Yoshito Mizoguchi ◽  
Yoshiomi Imamura ◽  
Shigeto Yamada ◽  
Takefumi Ueno ◽  
...  
Keyword(s):  
Elderly People ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Brain Volume ◽  
Brain Mri ◽  
Statistical Parametric Mapping ◽  
Clinical Dementia Rating ◽  
Amygdala Volume ◽  
State Examination

Abstract Oxytocin is deeply involved in human relations. In recent years, it is becoming clear that oxytocin is also involved in social cognition and social behaviour. Oxytocin receptors are also thought to be present in the hippocampus and amygdala, and the relationship between oxytocin and the structure and function of the hippocampus and amygdala has been reported. However, a few studies have investigated oxytocin and its relationship to hippocampus and amygdala volume in elderly people. The aim of this study is to investigate the association between serum oxytocin levels and hippocampus and amygdala volume in elderly people. The survey was conducted twice in Kurokawa-cho, Imari, Saga Prefecture, Japan, among people aged 65 years and older. We collected data from 596 residents. Serum oxytocin level measurements, brain MRI, Mini–Mental State Examination and Clinical Dementia Rating were performed in Time 1 (2009–11). Follow-up brain MRI, Mini–Mental State Examination and Clinical Dementia Rating were performed in Time 2 (2016–17). The interval between Time 1 and Time 2 was about 7 years. Fifty-eight participants (14 men, mean age 72.36 ± 3.41 years, oxytocin 0.042 ± 0.052 ng/ml; 44 women, mean age 73.07 ± 4.38 years, oxytocin 0.123 ± 0.130 ng/ml) completed this study. We analysed the correlation between serum oxytocin levels (Time 1) and brain volume (Time 1, Time 2 and Times 1–2 difference) using voxel-based morphometry implemented with Statistical Parametric Mapping. Analysis at the cluster level (family-wise error; P < 0.05) showed a positive correlation between serum oxytocin levels (Time 1) and brain volume of the region containing the left hippocampus and amygdala (Time 2). This result suggests that oxytocin in people aged 65 years and older may be associated with aging-related changes in hippocampus and amygdala volume.

P2-149: The Mini-Mental State Examination gradient in community healthy elderly subjects, mild cognitive impairment and mild dementia

2010 ◽  
Vol 6 ◽  
pp. S357-S357
Author(s):  
Lívia G. Rodrigues ◽  
Ana Luiza Camozzato ◽  
Renata Kochhann ◽  
Claudia Godinho ◽  
Maria Otilia Cerveira ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Elderly Subjects ◽  
Mild Dementia ◽  
Healthy Elderly ◽  
State Examination ◽  
Healthy Elderly Subjects

Educational level differences on the Mini-Mental State: the role of test bias

1988 ◽  
Vol 18 (3) ◽  
pp. 727-731 ◽  
Author(s):  
A. F. Jorm ◽  
R. Scott ◽  
A. S. Henderson ◽  
D. W. K. Kay
Keyword(s):  
Cognitive Impairment ◽  
Elderly People ◽  
Mental State ◽  
Educational Level ◽  
Mini Mental State Examination ◽  
Community Sample ◽  
Test Bias ◽  
Level Difference ◽  
State Examination

SynopsisLess educated elderly people are commonly found to perform more poorly on the Mini-Mental State Examination (MMSE). This educational level difference has been attributed by some research workers to test bias. To assess whether the MMSE is biased against the poorly educated, its validity was assessed separately in the more- and less-educated members of a community sample. No evidence was found to indicate that the test is a biased measure of cognitive impairment.

scholarly journals Comparison of Mini-Mental State Examination (Mmse) and Bangla Mini-Mental State Examination (Mmse-B) Among Healthy Elderly in Bangladesh

2016 ◽  
Vol 24 (1) ◽  
pp. 30-35 ◽  
Author(s):  
Swapon Kumar Ghose ◽  
Ahmed Hossain Chowdhury ◽  
ATM Hasibul Hasan ◽  
Muhammad Zillur Rahman Khan ◽  
ASM Rezaul Karim ◽  
...  
Keyword(s):  
Mental State ◽  
Rural Areas ◽  
Mini Mental State Examination ◽  
Cognitive Domain ◽  
College Hospital ◽  
Level Of Education ◽  
Medical College ◽  
Healthy Elderly ◽  
The Mean ◽  
State Examination

Objective: The aim of the present study was to compare the efficacy of modified Bangla version of mini mental state examination (MMSE-B) with mini mental state examination (MMSE) for using among Bangladeshi healthy elderly.Methods: This is a descriptive type of observational study carried out in Department of Neurology, Dhaka Medical College Hospital, Dhaka, from January to December of 2013. A total of 200 healthy elderly (patient attendants at the clinic) who met the inclusion criteria, were interviewed using a structured questionnaire containing information on age, sex, residence, educational backgrounds and questions set at MMSE English version (MMSE-E) and modified Bangla version for MMSE-B (Figure-1). MMSE and MMSE-B both were applied in 1:1 ration. The literate people were asked whether they are comfortable to answer in English (MMSE-E) or they would like the translated form and we applied the form of MMSE (MMSE-T) according to their wish. But in other group of people the modified Bangla version (MMSE-B) was used irrespective of level of education.Results: The mean age at presentation was 58.1±7.8 and 94% were within 50-70 years of age. Male were more common (80, 66) in both the groups and most of them belonging to rural areas. MMSE-B were mostly employed on people having only primary level of education (up to class five, n=80) or no education (n=2), whereas MMSE-E were employed up on people having a level of education higher than class five (n=96). Every question in each item of cognitive domain correlated well (correlation co-efficient range from 0.801- 0.971) except the 7th (correlation co-efficient 0.418) which had higher mean score for MMSE-B than those of MMSE-E (0.90 versus 0.54). The mean score of MMSE-B was greater than the mean score of MMSE-E for most of questions except the 1st question that is related to orientation of time. The mean of total score in MMSE-E and MMSE-B were 24.04 and 24.91 respectively with a correlation co-efficient of 0.940.Conclusion: MMSE-B is comparable to MMSE and it is even better in some segments of cognitive assessment for using among Bangladeshi people irrespective of level of education.J Dhaka Medical College, Vol. 24, No.1, April, 2015, Page 30-35

scholarly journals To evaluate the utility of 10 warning signs questionnaire in assessment of cognitive function among elderly people

2016 ◽  
Vol 7 (01) ◽  
pp. 168-170
Author(s):  
Sunil Kumar Raina ◽  
Vishav Chander
Keyword(s):  
Cognitive Impairment ◽  
Elderly People ◽  
Mental State ◽  
Mini Mental State Examination ◽  
The Elderly ◽  
Warning Signs ◽  
Correlation Data ◽  
Urban Rural ◽  
State Examination

ABSTRACT Introduction: Routine screening of high-risk elderly people for early cognitive impairment using mini-mental state examination (MMSE) and its modifications may be constrained by demographic and other variables. Warning signs (as reported by family/caregivers) may be a useful alternative. The present data analysis was carried out with the aim to identify the role of 10 warning signs screen as an alternative tool for screening for cognitive impairment among elderly. Materials and Methods: For the purpose of this analysis (correlation), data available with us from a study conducted on the elderly population (60 years and above) from selected geographical areas (Migrant, Urban, Rural, and Tribal) of Himachal Pradesh was used. Results: A high statistically significant was found between scores on 10 warning signs screen and Hindi mental state examination/Bharmouri mental state examination (modifications of MMSE). Conclusions: Ten warning signs screen can be an important screening total for assessment of cognitive impairment in the elderly Indians.

scholarly journals Associations between Commonly Used Characteristics in Frailty Assessment and Mental State in Frail Elderly People

Proceedings ◽  
2018 ◽  
Vol 2 (19) ◽  
pp. 1247 ◽  
Author(s):  
Iván González ◽  
Rocío Garrido ◽  
Fco Navarro ◽  
Jesús Fontecha ◽  
Ramón Hervás ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Cognitive Decline ◽  
Elderly People ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Multiple Logistic Regression ◽  
Frail Elders ◽  
Frailty Assessment ◽  
The Impact ◽  
State Examination

This paper presents a cross-sectional study to analyze the impact on cognitive decline of a set of characteristics used for frailty assessment in elderly people. Considered characteristics come from several dimensions, including anthropometric, biological, nutritional, functional and mobility. Cognitive functioning is estimated by the Mini-Mental State Examination test. Additionally, mobility dimension is assessed from two perspectives: one based on direct observation of ambulation through subjective gait analyses; and the other performing explicit gait trials by using the instrumentation provided. In order to accomplish the purpose of this research, a multiple logistic regression analysis is carried out. Variables are grouped according to popular and/or standardized categories adopted in other clinical studies. Mini-Mental State Examination represents the dependent variable, while the characteristics for frailty assessment make up the set of explanatory variables. The multiple logistic regression is performed using a sample of 81 frail elders from two nursing homes in Spain. The results obtained indicate that frail elders aged 90 years of older, with moderate dependence in daily functioning, moderate risk of falls and with a stride interval gait variability greater than 6% were most likely to suffer cognitive decline, representing what is called cognitive frails.

scholarly journals Adapting Bangla Mini-Mental State Examination (MMSE-B) among Healthy Elderly in Bangladesh

2016 ◽  
Vol 32 (2) ◽  
pp. 91-97
Author(s):  
Swapon Kumar Ghose ◽  
Kazi Gias Uddin Ahmed ◽  
Ahmed Hossian Chowdhury ◽  
ATM Hasibul Hasan ◽  
Muhammad Zillur Rahman Khan ◽  
...  
Keyword(s):  
Mental State ◽  
Rural Areas ◽  
Mini Mental State Examination ◽  
Cognitive Domain ◽  
Level Of Education ◽  
Educational Backgrounds ◽  
Healthy Elderly ◽  
The Mean ◽  
Well Correlation ◽  
State Examination

Background: The aim of our study was to determine whether modified Bangla version (MMSE-B) is as effective as mini mental state examination (MMSE) tool for use in Bangladeshi people. Methods: This descriptive observational study was carried out in Department of Neurology, DMCH from January 2013 to December 2013. A total 200 healthy adults (patient attendants at the clinic) who met the inclusion criteria, were interviewed using a structured questionnaire containing information on age, sex, residence, educational backgrounds and questions set at MMSE English version (MMSE-E) and modified Bangla version for MMSE-B (Figure-1). MMSE and MMSE-B both were applied in 1:1 ration. The literate people were asked whether they are comfortable to answer in English (MMSE-E) or they would like the translated form and we applied the form of MMSE (MMSE-T) according to their wish. But in other group of people the modified Bangla version (MMSE-B) was used irrespective of level of education. Result: The mean age at presentation was 58.1±7.8 and 94% were within 50-70 years of age. Male were more common (80, 66) in both the groups and most of them belonging to rural areas. MMSE-B were mostly employed on people having only primary level of education (up to class five, n=80) or no education (n=2), whereas MMSE-E were employed up on people having a level of education higher than class five (n=96). Every question in each item of cognitive domain correlated well (correlation co-efficient range from 0.801- 0.971) except the 7th (correlation co-efficient 0.418) which had higher mean score for MMSE-B than those of MMSE-E (0.90 versus 0.54). The mean score of MMSEB was greater than the mean score of MMSE-E for most of questions except the 1st question that is related to orientation of time. The mean of total score in MMSE-E and MMSE-B were 24.04 and 24.91 respectively with a correlation co-efficient of 0.940. Conclusion: MMSE-B is adaptable for use in Bangladeshi people irrespective of level of education. Bangladesh Journal of Neuroscience 2016; Vol. 32 (2): 91-97

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