Three zinc-finger RNA-binding proteins in cabbage (Brassica rapa) play diverse roles in seed germination and plant growth under normal and abiotic stress conditions

2016 ◽  
Vol 159 (1) ◽  
pp. 93-106 ◽  
Author(s):  
Ye Rin Park ◽  
Min Ji Choi ◽  
Su Jung Park ◽  
Hunseung Kang
Keyword(s):  
Abiotic Stress ◽  
Seed Germination ◽  
Plant Growth ◽  
Zinc Finger ◽  
Brassica Rapa ◽  
Binding Proteins ◽  
Rna Binding ◽  
Rna Binding Proteins ◽  
Stress Conditions

scholarly journals Roles of Organellar RNA-Binding Proteins in Plant Growth, Development, and Abiotic Stress Responses

2020 ◽  
Vol 21 (12) ◽  
pp. 4548 ◽  
Author(s):  
Kwanuk Lee ◽  
Hunseung Kang
Keyword(s):  
Abiotic Stress ◽  
Plant Growth ◽  
Stress Responses ◽  
Translational Control ◽  
Binding Proteins ◽  
Rna Binding ◽  
Rna Binding Proteins ◽  
Rna Metabolism ◽  
Functional Roles ◽  
Growth Development

Organellar gene expression (OGE) in chloroplasts and mitochondria is primarily modulated at post-transcriptional levels, including RNA processing, intron splicing, RNA stability, editing, and translational control. Nucleus-encoded Chloroplast or Mitochondrial RNA-Binding Proteins (nCMRBPs) are key regulatory factors that are crucial for the fine-tuned regulation of post-transcriptional RNA metabolism in organelles. Although the functional roles of nCMRBPs have been studied in plants, their cellular and physiological functions remain largely unknown. Nevertheless, existing studies that have characterized the functions of nCMRBP families, such as chloroplast ribosome maturation and splicing domain (CRM) proteins, pentatricopeptide repeat (PPR) proteins, DEAD-Box RNA helicase (DBRH) proteins, and S1-domain containing proteins (SDPs), have begun to shed light on the role of nCMRBPs in plant growth, development, and stress responses. Here, we review the latest research developments regarding the functional roles of organellar RBPs in RNA metabolism during growth, development, and abiotic stress responses in plants.

Characterization of glycine-rich RNA-binding proteins inBrassica napusunder stress conditions

2012 ◽  
Vol 146 (3) ◽  
pp. 297-307 ◽  
Author(s):  
Min Kyung Kim ◽  
Hyun Ju Jung ◽  
Dong Hyun Kim ◽  
Hunseung Kang
Keyword(s):  
Binding Proteins ◽  
Rna Binding ◽  
Rna Binding Proteins ◽  
Stress Conditions

scholarly journals ALY RNA-Binding Proteins Are Required for Nucleocytosolic mRNA Transport and Modulate Plant Growth and Development

2018 ◽  
Vol 177 (1) ◽  
pp. 226-240 ◽  
Author(s):  
Christina Pfaff ◽  
Hans F. Ehrnsberger ◽  
María Flores-Tornero ◽  
Brian B. Sørensen ◽  
Thomas Schubert ◽  
...  
Keyword(s):  
Plant Growth ◽  
Growth And Development ◽  
Binding Proteins ◽  
Rna Binding ◽  
Rna Binding Proteins ◽  
Plant Growth And Development ◽  
Mrna Transport

scholarly journals The Tristetraprolin Family of RNA-Binding Proteins in Cancer: Progress and Future Prospects

Cancers ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1539 ◽  
Author(s):  
Yogesh Saini ◽  
Jian Chen ◽  
Sonika Patial
Keyword(s):  
Gene Expression ◽  
Transcriptional Regulation ◽  
Zinc Finger ◽  
Binding Proteins ◽  
Rna Binding ◽  
Zinc Finger Protein ◽  
Rna Binding Proteins ◽  
Regulation Of Gene Expression ◽  
Finger Protein ◽  
Post Transcriptional Regulation

Post-transcriptional regulation of gene expression plays a key role in cellular proliferation, differentiation, migration, and apoptosis. Increasing evidence suggests dysregulated post-transcriptional gene expression as an important mechanism in the pathogenesis of cancer. The tristetraprolin family of RNA-binding proteins (RBPs), which include Zinc Finger Protein 36 (ZFP36; commonly referred to as tristetraprolin (TTP)), Zinc Finger Protein 36 like 1 (ZFP36L1), and Zinc Finger Protein 36 like 2 (ZFP36L2), play key roles in the post-transcriptional regulation of gene expression. Mechanistically, these proteins function by binding to the AU-rich elements within the 3′-untranslated regions of their target mRNAs and, in turn, increasing mRNA turnover. The TTP family RBPs are emerging as key regulators of multiple biological processes relevant to cancer and are aberrantly expressed in numerous human cancers. The TTP family RBPs have tumor-suppressive properties and are also associated with cancer prognosis, metastasis, and resistance to chemotherapy. Herein, we summarize the various hallmark molecular traits of cancers that are reported to be regulated by the TTP family RBPs. We emphasize the role of the TTP family RBPs in the regulation of trait-associated mRNA targets in relevant cancer types/cell lines. Finally, we highlight the potential of the TTP family RBPs as prognostic indicators and discuss the possibility of targeting these TTP family RBPs for therapeutic benefits.

scholarly journals Zinc Finger-like Motif Conserved in a Family of RNA Binding Proteins

1997 ◽  
Vol 61 (5) ◽  
pp. 905-906 ◽  
Author(s):  
Yuichi Matsushima ◽  
Kiyoshi Matsumura ◽  
Yasuo Kitagawa
Keyword(s):  
Zinc Finger ◽  
Binding Proteins ◽  
Rna Binding ◽  
Rna Binding Proteins

Comparative analysis of Arabidopsis zinc finger-containing glycine-rich RNA-binding proteins during cold adaptation

2010 ◽  
Vol 48 (10-11) ◽  
pp. 866-872 ◽  
Author(s):  
Won Yong Kim ◽  
Joo Yeol Kim ◽  
Hyun Ju Jung ◽  
Seung Han Oh ◽  
Yeon Soo Han ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Zinc Finger ◽  
Cold Adaptation ◽  
Binding Proteins ◽  
Rna Binding ◽  
Rna Binding Proteins

scholarly journals Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins

2011 ◽  
Vol 12 (1) ◽  
pp. R3 ◽  
Author(s):  
Tanja Scherrer ◽  
Christian Femmer ◽  
Ralph Schiess ◽  
Ruedi Aebersold ◽  
André P Gerber
Keyword(s):  
Zinc Finger ◽  
Binding Proteins ◽  
Rna Binding ◽  
Rna Binding Proteins
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