scholarly journals Incidence, antibiotic treatment and outcomes of lactational mastitis: Findings from The Norwegian Mother, Father and Child Cohort Study (MoBa)

2021 ◽  
Author(s):  
Luke E. Grzeskowiak ◽  
Moni R. Saha ◽  
Wendy V. Ingman ◽  
Hedvig Nordeng ◽  
Eivind Ystrom ◽  
...  
Keyword(s):  
Cohort Study ◽  
Antibiotic Treatment ◽  
Lactational Mastitis

scholarly journals An observational cohort study of bacterial co-infection and implications for empirical antibiotic therapy in patients presenting with COVID-19 to hospitals in North West London

2020 ◽  
Author(s):  
Liyang Wang ◽  
Amit K Amin ◽  
Priya Khanna ◽  
Adnan Aali ◽  
Alastair McGregor ◽  
...  
Keyword(s):  
Cohort Study ◽  
Antibiotic Treatment ◽  
Inflammatory Markers ◽  
White Cell Count ◽  
Antimicrobial Treatment ◽  
Observational Cohort Study ◽  
North West ◽  
Empirical Antibiotic Treatment ◽  
Significant Difference ◽  
Observational Cohort

Abstract Objectives To describe the prevalence and nature of bacterial co-infections in COVID-19 patients within 48 hours of hospital admission and assess the appropriateness of empirical antibiotic treatment they received. Methods In this retrospective observational cohort study, we included all adult non-pregnant patients who were admitted to two acute hospitals in North West London in March and April 2020 and confirmed to have COVID-19 infection within 2 days of admission. Results of microbiological specimens taken within 48 hours of admission were reviewed and their clinical significance was assessed. Empirical antibiotic treatment of representative patients was reviewed. Patient age, gender, co-morbidities, inflammatory markers at admission, admission to ICU and 30 day all-cause in-hospital mortality were collected and compared between patients with and without bacterial co-infections. Results Of the 1396 COVID-19 patients included, 37 patients (2.7%) had clinically important bacterial co-infection within 48 hours of admission. The majority of patients (36/37 in those with co-infection and 98/100 in selected patients without co-infection) received empirical antibiotic treatment. There was no significant difference in age, gender, pre-existing illnesses, ICU admission or 30 day all-cause mortality in those with and without bacterial co-infection. However, white cell count, neutrophil count and CRP on admission were significantly higher in patients with bacterial co-infections. Conclusions We found that bacterial co-infection was infrequent in hospitalized COVID-19 patients within 48 hours of admission. These results suggest that empirical antimicrobial treatment may not be necessary in all patients presenting with COVID-19 infection, although the decision could be guided by high inflammatory markers.

scholarly journals Antibiotic treatment during early childhood and risk of type 1 diabetes in children: A national birth cohort study

2020 ◽  
Vol 21 (8) ◽  
pp. 1457-1464
Author(s):  
Julie Christine Antvorskov ◽  
Camilla Schmidt Morgen ◽  
Karsten Buschard ◽  
Tine Jess ◽  
Kristine Højgaard Allin ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Early Childhood ◽  
Cohort Study ◽  
Birth Cohort ◽  
Antibiotic Treatment ◽  
Birth Cohort Study

Long-Term Outcome of Patients with Acute Cholecystitis Receiving Antibiotic Treatment: A Retrospective Cohort Study

2013 ◽  
Vol 38 (2) ◽  
pp. 347-354 ◽  
Author(s):  
Chih-Hung Wang ◽  
Hao-Chang Chou ◽  
Kao-Lang Liu ◽  
Wan-Ching Lien ◽  
Hsiu-Po Wang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Acute Cholecystitis ◽  
Antibiotic Treatment ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Term Outcome ◽  
Long Term Outcome
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