Head circumference at birth and childhood developmental disorders in a nationwide cohort in Denmark

2018 ◽  
Vol 32 (5) ◽  
pp. 458-466 ◽  
Author(s):  
Kristina Aagaard ◽  
Cathrine Carlsen Bach ◽  
Tine Brink Henriksen ◽  
René Tidemand Larsen ◽  
Niels Bjerregård Matthiesen
Keyword(s):  
Head Circumference ◽  
Developmental Disorders ◽  
Childhood Developmental Disorders

Head Circumference in Autism and Other Pervasive Developmental Disorders

1996 ◽  
Vol 37 (6) ◽  
pp. 665-671 ◽  
Author(s):  
Wendy Woodhouse ◽  
Anthony Bailey ◽  
Michael Rutter ◽  
Patrick Bolton ◽  
Gillian Baird ◽  
...  
Keyword(s):  
Head Circumference ◽  
Pervasive Developmental Disorders ◽  
Developmental Disorders

scholarly journals Tocolytic treatment and childhood allergic disorders: The Japan Environment and Children’s Study

2021 ◽  
Author(s):  
Tsuyoshi Murata ◽  
Hirotaka Isogami ◽  
Karin Imaizumi ◽  
Toma Fukuda ◽  
Hyo Kyozuka ◽  
...  
Keyword(s):  
Lower Incidence ◽  
Developmental Disorders ◽  
Reference Group ◽  
Group Differences ◽  
Obstetric Outcomes ◽  
Maternal Characteristics ◽  
Term Births ◽  
Allergic Disorders ◽  
Tocolytic Agents ◽  
Childhood Developmental Disorders

Background: This study aimed to evaluate differences in maternal characteristics and obstetric and childhood outcomes between term births according to the use of tocolytic treatment. Methods: This study analyzed the data of the participants enrolled in the Japan Environment and Children’s Study between 2011 and 2014. Data of 63,409 women with singleton births after 37 weeks of gestation were analyzed. We compared maternal characteristics, obstetric outcomes, and childhood outcomes between term births with tocolytic treatment and those without tocolytic treatment. Multiple logistic regression was used to calculate adjusted odds ratios for childhood outcomes with significant between-group differences in the univariable analysis for term births with tocolytic agents, with term births without tocolytic agents as the reference group. Results: In term births with tocolytic agents, participants had significantly younger age, leaner body mass index, higher oxidative stress during pregnancy, shorter pregnancy period, lighter neonatal birth weight, lower incidence of gestational diabetes mellitus, higher incidence of preterm premature rupture of membrane, higher rates of cesarean section, lower incidence of meconium-stained amniotic fluid during pregnancy, and higher incidence of childhood allergic disorders. The incidence of childhood developmental disorders showed no significant between-group differences. The adjusted odds ratio for childhood allergic disorders in term births with tocolytic agents was 1.09 (95% confidence interval, 1.04-1.14). Conclusions: This study found no significant association between tocolytic treatment and the incidence of childhood developmental disorders in children with term births. However, tocolytic treatment showed an association with a slightly increased incidence of childhood allergic disorders.

scholarly journals Abnormal Head Size in Children and Adolescents with Congenital Nervous System Disorders or Neurological Syndromes with One or More Neurodysfunction Visible since Infancy

2020 ◽  
Vol 9 (11) ◽  
pp. 3739
Author(s):  
Lidia Perenc ◽  
Agnieszka Guzik ◽  
Justyna Podgórska-Bednarz ◽  
Mariusz Drużbicki
Keyword(s):  
Nervous System ◽  
Children And Adolescents ◽  
Head Circumference ◽  
Developmental Disorders ◽  
Neuromuscular Disorders ◽  
Head Size ◽  
Z Score ◽  
Significant Relationships ◽  
Progressive Encephalopathy ◽  
Abnormal Head

The current study was designed to investigate co-occurrence of absolute/relative microcephaly, absolute/relative macrocephaly and congenital nervous system disorders or neurological syndromes with symptoms visible since infancy, based on fundamental data acquired during the admission procedure at a neurological rehabilitation ward for children and adolescents. The study applied a retrospective analysis of data collected during the hospitalization of 327 children and adolescents, aged 4–18 years, affected since infancy by congenital disorders of the nervous system and/or neurological syndromes associated with a minimum of one neurodysfunction. To identify subjects with absolute/relative microcephaly, absolute/relative macrocephaly in the group of children and adolescents, the adopted criteria took into account z-score values for head circumference (z-score hc) and head circumference index (z-score HCI). Dysmorphological (x+/−3s) and traditional (x+/−2s) criteria were adopted to diagnose developmental disorders of head size. Regardless of the adopted criteria, absolute macrocephaly often coexists with state after surgery of lumbar myelomeningocele and hydrocephalus, isolated hydrocephalus, hereditary motor and sensory polyneuropathy, and Becker’s muscular dystrophy (p < 0.001, p = 0.002). Absolute macrocephaly is often associated with neural tube defects and neuromuscular disorders (p = 0.001, p = 0.001). Relative microcephaly often occurs with non-progressive encephalopathy (p = 0.017, p = 0.029). Absolute microcephaly, diagnosed on the basis of traditional criteria, is often associated with epilepsy (p = 0.043). In children and adolescents with congenital nervous system disorders or neurological syndromes with one or more neurodysfunction visible since infancy, there is variation in abnormal head size (statistically significant relationships and clinical implications were established). The definitions used allowed for the differentiation of abnormal head size.

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