scholarly journals The Role of Preterm Birth in the Association Between Opioid Maintenance Therapy and Neonatal Abstinence Syndrome

2018 ◽  
Vol 32 (2) ◽  
pp. 213-222 ◽  
Author(s):  
Lara S. Lemon ◽  
Ashley Naimi ◽  
Steve N. Caritis ◽  
Robert W. Platt ◽  
Raman Venkataramanan ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Maintenance Therapy ◽  
Neonatal Abstinence Syndrome ◽  
Abstinence Syndrome ◽  
Opioid Maintenance Therapy

scholarly journals A Swedish Population-based Study of Adverse Birth Outcomes among Pregnant Women Treated with Buprenorphine or Methadone: Preliminary Findings

2016 ◽  
Vol 10 ◽  
pp. SART.S38887
Author(s):  
Keele E. Wurst ◽  
Barbara K. Zedler ◽  
Andrew R. Joyce ◽  
Maciek Sasinowski ◽  
E. Lenn Murrelle
Keyword(s):  
Preterm Birth ◽  
General Population ◽  
Pregnant Women ◽  
Birth Outcomes ◽  
Congenital Malformations ◽  
Mode Of Delivery ◽  
Neonatal Abstinence Syndrome ◽  
Adverse Birth Outcomes ◽  
Abstinence Syndrome ◽  
Opioid Agonist

Background Untreated opioid dependence in pregnant women is associated with adverse birth outcomes. Buprenorphine and methadone are options for opioid agonist medication-assisted treatment during pregnancy. Objective The aim of this study was to describe adverse birth outcomes observed with buprenorphine or methadone treatment compared to the general population in Sweden. Methods Pregnant women and their corresponding births during 2005–2011 were identified in the Swedish Medical Birth Register. Data on stillbirth, neonatal/infant death, mode of delivery, gestational age at birth, Apgar score, growth outcomes, neonatal abstinence syndrome, and congenital malformations were examined. Frequencies were compared using two-sided Fisher's exact tests. Unadjusted estimates of birth outcomes for women treated with buprenorphine or methadone were compared to the registered general population. Results A total of 746,257 pregnancies among 538,178 unique women resulted in 746,485 live births. Among the 194 women treated with buprenorphine ( N = 176) or methadone ( N = 52), no stillbirths or neonatal/infant deaths occurred. Neonatal abstinence syndrome developed in 23.3% and 38.5% of infants born to mothers treated with buprenorphine and methadone, respectively. The frequency of the selected adverse birth outcomes assessed in women treated with buprenorphine as compared to the general population was not significantly different. However, a significantly higher frequency of preterm birth and congenital malformations was observed in women treated with methadone as compared to the general population. Compared with the general population, methadone-treated women were significantly older than buprenorphine-treated women, and both treatment groups began prenatal care later, were more likely to smoke cigarettes, and did not cohabitate with the baby's father. Conclusions An increased frequency of the selected adverse birth outcomes was not observed with buprenorphine treatment during pregnancy. Twofold increased frequency of preterm birth [2.21 (1.11, 4,41)] and congenital malformations [2.05 (1.08, 3.87)] was observed in the methadone group, which may be partly explained by older average maternal age and differences in other measured and unmeasured confounders.

Role of Clonidine in Neonatal Abstinence Syndrome

2016 ◽  
Vol 50 (4) ◽  
pp. 301-310 ◽  
Author(s):  
Vonya N. Streetz ◽  
Brooke L. Gildon ◽  
Dennis F. Thompson
Keyword(s):  
Neonatal Abstinence Syndrome ◽  
Abstinence Syndrome

scholarly journals The Role of Stigma in the Nursing Care of Families Impacted by Neonatal Abstinence Syndrome

2020 ◽  
Vol 20 (5) ◽  
pp. 354-363
Author(s):  
Pamela Recto ◽  
Kelly McGlothen-Bell ◽  
Jacqueline McGrath ◽  
Elizabeth Brownell ◽  
Lisa M. Cleveland
Keyword(s):  
Nursing Care ◽  
Neonatal Abstinence Syndrome ◽  
Abstinence Syndrome

scholarly journals Neonatal abstinence syndrome in methadone exposed infants: Role of genetic variability

2015 ◽  
Vol 146 ◽  
pp. e277 ◽  
Author(s):  
Andrea L. Fielder ◽  
J.K. Coller ◽  
M.R. Hutchinson ◽  
Ross R. Haslam ◽  
Nona Lu ◽  
...  
Keyword(s):  
Genetic Variability ◽  
Neonatal Abstinence Syndrome ◽  
Abstinence Syndrome

Utilizing Accelerometers As a Novel Technology for Assessment of Neonatal Abstinence Syndrome

PEDIATRICS ◽  
2016 ◽  
Vol 137 (Supplement 3) ◽  
pp. 197A-197A
Author(s):  
Katherine M. Somers ◽  
Ashley R. Taylor ◽  
Andrew Jung ◽  
Alfred Wicks ◽  
Andre A. Muelenaer
Keyword(s):  
Neonatal Abstinence Syndrome ◽  
Abstinence Syndrome ◽  
Novel Technology
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