Prevalence of Neural Tube Defects and the Impact of Prenatal Diagnosis in Three Districts of Beijing, China

2017 ◽  
Vol 31 (4) ◽  
pp. 293-300 ◽  
Author(s):  
Lei Jin ◽  
Lei Jin ◽  
Jingru Yu ◽  
Yanjun Xu ◽  
Hui Liu ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Neural Tube ◽  
Neural Tube Defects ◽  
The Impact ◽  
Beijing China

Impact of Prenatal Diagnosis on the Birth Prevalence of Neural Tube Defects, Atlanta, 1990-4991

PEDIATRICS ◽  
1995 ◽  
Vol 96 (5) ◽  
pp. 880-883
Author(s):  
Helen E. Roberts ◽  
Cynthia A. Moore ◽  
Janet D. Cragan ◽  
Paul M. Fernhoff ◽  
Muin J. Khoury
Keyword(s):  
Prenatal Diagnosis ◽  
Neural Tube ◽  
Neural Tube Defects ◽  
Fetal Death ◽  
Population Based ◽  
Congenital Defects ◽  
Substantial Impact ◽  
Birth Prevalence ◽  
Live Births ◽  
The Impact

Objective. To determine the impact of prenatal diagnosis on the birth prevalence of neural tube defects (NTDs) in Atlanta during 1990 through 1991. Methods. Live-born and stillborn infants with NTDs who were at least 20 weeks' gestation were ascertained by the Metropolitan Atlanta Congenital Defects Program (MACDP), a population-based birth defects registry. Prenatally diagnosed NTD-affected pregnancies were ascertained from the four perinatal centers and the three genetic laboratories operating in Atlanta during 1990 through 1991. Fetal death certificates were also reviewed for potential cases. Results. During 1990 through 1991, MACDP ascertained 59 NTD cases, for a birth prevalence of 0.77/1000 live births. During this period, an additional 28 NTD-affected pregnancies were detected prenatally and terminated before 20 weeks' gestation. The adjusted NTD rate during 1990 through 1991, which includes prenatally diagnosed cases, was 1.13/1000 live births. Conclusions. Prenatal diagnosis is making a substantial impact on the birth prevalence of NTDs in Atlanta. However, since NTD rates in Atlanta were 2 to 2.5 per 1000 live births in 1970, prenatal diagnosis and termination of pregnancy does not completely account for the declining rate of NTDs.

PRENATAL DIAGNOSIS OF NEURAL-TUBE DEFECTS WITH A MONOCLONAL ANTIBODY SPECIFIC FOR ACETYLCHOLINESTERASE

The Lancet ◽  
1985 ◽  
Vol 325 (8419) ◽  
pp. 5-8 ◽  
Author(s):  
DavidJ.H. Brock ◽  
Lilias Barron ◽  
VeronicaVan Heyningen
Keyword(s):  
Monoclonal Antibody ◽  
Prenatal Diagnosis ◽  
Neural Tube ◽  
Neural Tube Defects

scholarly journals Prenatal Diagnosis of Neural Tube Defects

1981 ◽  
Vol 9 (4) ◽  
pp. 159-161
Author(s):  
J. N. Macri ◽  
D. A. Baker
Keyword(s):  
Prenatal Diagnosis ◽  
Neural Tube ◽  
Neural Tube Defects
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