scholarly journals Maternal Pre-pregnancy Body Mass Index and Autism Spectrum Disorder among Offspring: A Population-Based Case-Control Study

2016 ◽  
Vol 30 (5) ◽  
pp. 479-487 ◽  
Author(s):  
Kelly D. Getz ◽  
Marlene T. Anderka ◽  
Martha M. Werler ◽  
Susan S. Jick
Keyword(s):  
Body Mass Index ◽  
Autism Spectrum Disorder ◽  
Body Mass ◽  
Case Control Study ◽  
Population Based ◽  
Autism Spectrum ◽  
Case Control ◽  
Spectrum Disorder ◽  
Control Study

Placental Gross Pathology in a Population Based Case-Control Study of Autism Spectrum Disorder

Placenta ◽  
2021 ◽  
Vol 112 ◽  
pp. e48
Author(s):  
Serena Chen ◽  
Christine Chen ◽  
Mehrin Jan ◽  
Jennifer Feng ◽  
Joan Krickellas ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Case Control Study ◽  
Population Based ◽  
Autism Spectrum ◽  
Case Control ◽  
Spectrum Disorder ◽  
Gross Pathology ◽  
Control Study

scholarly journals Parental exposures to occupational asthmagens and risk of autism spectrum disorder in a Danish population-based case-control study

2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Alison B. Singer ◽  
Igor Burstyn ◽  
Malene Thygesen ◽  
Preben Bo Mortensen ◽  
M. Daniele Fallin ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Case Control Study ◽  
Population Based ◽  
Autism Spectrum ◽  
Case Control ◽  
Spectrum Disorder ◽  
Danish Population ◽  
Control Study

Comparing sleep patterns between children with autism spectrum disorder and children with typical development: A matched case–control study

Autism ◽  
2020 ◽  
Vol 24 (8) ◽  
pp. 2298-2303
Author(s):  
Andy CY Tse ◽  
CCW Yu ◽  
Paul H Lee
Keyword(s):  
Body Mass Index ◽  
Autism Spectrum Disorder ◽  
Body Mass ◽  
Sleep Onset ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Case Control ◽  
Spectrum Disorder ◽  
Typical Development ◽  
Matched Case

Children with autism spectrum disorder are often reported to have more sleep deficits and poorer sleep quality compared with children with typical development. However, most previous studies have serious methodological limitations, such as varying sample sizes in the comparison groups, wide age range of participants, and body mass index not matched between participants. This study investigated whether sleep patterns differed between children with autism spectrum disorder and those with typical development using a carefully matched case–control design and incorporating both actigraphy and sleep log assessments. A total of 78 children diagnosed with autism spectrum disorder were matched with 78 typical development controls in this study. The matched variables included age, gender, and body mass index. The results showed that children with autism spectrum disorder had shorter sleep duration, reduced sleep efficiency, longer sleep-onset latency, and longer wake after sleep onset than children with typical development ( ps < 0.05). Further studies are needed to explore the mechanisms underlying these sleep deficits in children with autism spectrum disorder. Lay abstract This study compared the sleep pattern between children with autism spectrum disorders and children with typical development using a matched case–control design (matched age, gender, and body mass index). Significant differences were found in night-time sleep duration (total amount of sleep at night), sleep efficiency (percentage of time spent asleep), sleep-onset latency (length of time that it takes to transit from awake to asleep), and wake after sleep onset (total amount of time spent awake after defined sleep onset). Findings showed that children with autism spectrum disorder had poorer sleep quality than children with typical development. Mechanisms underlying the differences should be further explored in order to develop an effective treatment intervention.

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