Assessment of the effects of loneliness, perceived social support, and depression on medication adherence in patients with ankylosing spondylitis

Author(s):  
Emine Öksüz ◽  
Fatma Ilknur Cinar ◽  
Muhammet Cinar ◽  
Emre Tekgoz ◽  
Sedat Yilmaz
2020 ◽  
Vol 55 (12) ◽  
pp. 1659-1669
Author(s):  
Alexandra Burton ◽  
Kate Walters ◽  
Louise Marston ◽  
David Osborn

Abstract Purpose People with severe mental illnesses (SMI) have an increased risk of cardiovascular disease (CVD). Research in the general population suggests that social support may protect against increased CVD morbidity and mortality; however, this may not apply to those with SMI. We aimed to explore the association between perceived social support and attendance at primary care nurse CVD risk reduction clinic appointments and CVD risk-reducing behaviours in an SMI population with elevated CVD risk factors. Methods We used longitudinal and cross-sectional data from a randomised controlled trial on 326 adults with SMI recruited via 76 general practices in England. Multilevel regression analysis estimated the effect of perceived social support on attendance at CVD risk reduction clinic appointments over 6 months, and adherence to CVD medication, physical activity, diet, smoking and alcohol use at baseline, adjusted by age, sex, ethnicity, deprivation, psychiatric diagnosis and employment. Results Perceived social support predicted greater appointment attendance in unadjusted (IRR = 1.005; 1.000–1.010; p = 0.05) but not adjusted analysis (IRR = 1.003; 0.998–1.009; p = 0.25). Perceived social support was associated with greater adherence to medication; for each 1% increase in social support, there was a 4.2% increase in medication adherence (OR = 1.042; 1.015–1.070; p = 0.002). No association was found between greater perceived social support and greater physical activity, lower sedentary behaviour, healthier diet, lower alcohol use or being a non-smoker. Conclusions Social support may be an important facilitator for CVD medication adherence and is potentially important for primary care appointment attendance; however, alternative strategies might be needed to help people with SMI engage in physical activity, healthier diets and to reduce their smoking and alcohol use.


2016 ◽  
Author(s):  
◽  
Deborah A. Mercier

Numerous research studies in the HIV literature have documented social support as a key factor influencing adherence to antiretroviral therapy (ART). This is one of only a few studies to examine perceived social support among adults living with HIV who have had repeated challenges with medication adherence. A secondary analysis of quantitative and qualitative data from two intervention studies was conducted using a mixed methods design. Two overarching themes were associated with the lack of social support: extreme isolation and constant turmoil. Subthemes, included loneliness, structural vulnerability, and emotional distress. Overall social support was low in this vulnerable group, especially when compared to the general population and to adults living with other chronic health conditions. Strong correlations existed between all social support subscales of the Medical Outcomes Study Social Support Survey (MOS-SSS). The strongest positive correlation was found between affectionate support and positive social interaction (r = .870, p = less than .0001). These data suggest that participants who frequently self-reported a lack of persons to spend time with socially often lacked positive, supportive relationships in their lives. No significant variation was found between self-reported overall social support or subscale scores based on age or health variables. Convergent qualitative data excerpts corresponded with low quantitative social support scores in every dimension, confirming that adults living with HIV who repeatedly struggle with taking life-long HIV medications lack social support in many areas of their lives.


2013 ◽  
Vol 58 (1) ◽  
pp. 59-65 ◽  
Author(s):  
Mark Rabinovitch ◽  
Clifford Cassidy ◽  
Norbert Schmitz ◽  
Ridha Joober ◽  
Ashok Malla

2020 ◽  
Vol 38 (4) ◽  
pp. 183-190
Author(s):  
Rabia Hacihasanoglu Asilar ◽  
Arzu Yildirim ◽  
Rabia Saglam ◽  
Ezgi Demirturk Selcuk ◽  
Yeliz Erduran ◽  
...  

2017 ◽  
Vol 29 (9) ◽  
pp. 1485-1493 ◽  
Author(s):  
Lauren B. Gerlach ◽  
Janet Kavanagh ◽  
Daphne Watkins ◽  
Claire Chiang ◽  
Hyungjin M. Kim ◽  
...  

ABSTRACTBackground:Social support has been shown to be an important factor in improving depression symptom outcomes, yet less is known regarding its impact on antidepressant medication adherence. This study sought to evaluate the role of perceived social support on adherence to new antidepressant medication prescriptions in later-life depression.Methods:Data from two prospective observational studies of participants ≥60 years old, diagnosed with depression, and recently prescribed a new antidepressant (N = 452). Perceived social support was measured using a subscale of the Duke Social Support Index and medication adherence was assessed using a validated self-report measure.Results:At four-month follow up, 68% of patients reported that they were adherent to antidepressant medication. Examining the overall sample, logistic regression analysis demonstrated no significant relationship between perceived social support and medication adherence. However, when stratifying the sample by social support, race, and gender, adherence significantly differed by race and gender in those with inadequate social support: Among those with low social support, African-American females were significantly less likely to adhere to depression treatment than white females (OR = 4.82, 95% CI = 1.14–20.28, p = 0.032) and white males (OR = 3.50, 95% CI = 1.03–11.92, p = 0.045).Conclusions:There is a significant difference in antidepressant medication adherence by race and gender in those with inadequate social support. Tailored treatment interventions for low social support should be sensitive to racial and gender differences.


2021 ◽  
Vol 20 (Supplement_1) ◽  
Author(s):  
R Lindsay-Rahman ◽  
TA Lennie ◽  
DK Moser ◽  
ML Chung

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): National Institute of Nursing Research grant Background Medication adherence is essential to improve health outcomes in patients with heart failure (HF). Depressive symptoms contribute to decrease adherence behaviors. Although social support is helpful to improving medication adherence, perceived social support (PSS) may differ by living arrangement. How social support and living arrangement contribute to the relationship between depressive symptoms and medication adherence is not well understood in patients with heart failure. Purpose The purpose of this study was to determine whether perceived social support and living arrangement moderated the association between depressive symptoms and medication adherence. Methods This was a secondary analysis from outpatients with HF. Depressive symptoms were measured by the Patient Health Questionnaire-9. Perceived social support was assessed using Multidimensional Scale of Perceived Social Support, and patients were grouped into high and low PSS groups using a score of 79, the upper tertile value. Medication adherence was measured objectively by a medication event monitoring system for 3-months. Living arrangement was classified as (1) living with a spouse, (2) living with non-spouse family or friend, or (3) living alone. Moderated moderation analysis was conducted using PROCESS macro (Model 3) in SPSS with 5,000 bootstrap samples. Results Of the total of 208 patients (mean age = 61 ± 11.5 years, 64% male), 60% lived with spouse, 22% lived with non-spousal family or friend, and 26% lived alone. Three-way interaction (depressive symptoms*living arrangement*PSS) was significant (p = 0.0324, Figure 1). The effect of depressive symptoms on medication adherence was only significant for two groups (Figure 2): the living alone group with high PSS (effect = - 4.1855, p = 0.0021), and the living with a non-spousal family group with low PSS (effect = -1.0180, p = 0.0349). For these groups, their depressive symptoms were inversely associated with medication adherence. Conclusions: These results suggest that living arrangement and perceived social support are factors to be considered in medication adherence when planning care for patients with depressive symptoms. Future research is needed to explore whether the combined intervention of improving depressive symptoms and social support focusing on instrumental social support effectively increases medication adherence.


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