Pulmonary tumor thrombotic microangiopathy associated with extramammary Paget's disease: An autopsy case report

2020 ◽  
Author(s):  
Yuzo Oyama ◽  
Haruto Nishida ◽  
Yoshihiko Kondo ◽  
Takahiro Kusaba ◽  
Hiroko Kadowaki ◽  
...  
Keyword(s):  
Case Report ◽  
Thrombotic Microangiopathy ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Extramammary Paget’S Disease ◽  
Autopsy Case ◽  
Pulmonary Tumor ◽  
Pulmonary Tumor Thrombotic Microangiopathy ◽  
Extramammary Paget's Disease

scholarly journals Pulmonary Tumor Thrombotic Microangiopathy Secondary to Extramammary Paget’s Disease: An Autopsy Case Report and Literature Review

2021 ◽  
pp. 1328-1332
Author(s):  
Akihiro Kato ◽  
Hiroshi Kato ◽  
Satoshi Komori ◽  
Satsuki Nakano ◽  
Takayuki Murase ◽  
...  
Keyword(s):  
Literature Review ◽  
Thrombotic Microangiopathy ◽  
Malignant Tumors ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Oral Drug ◽  
Extramammary Paget’S Disease ◽  
Pulmonary Tumor ◽  
Pulmonary Tumor Thrombotic Microangiopathy ◽  
Extramammary Paget's Disease

Pulmonary tumor thrombotic microangiopathy is a fatal disease secondary to some malignant tumors, such as gastric cancer, esophageal cancer, and pancreatic cancer. A 61-year-old man presented to our clinic with a red plaque with erosion on his scrotum and was diagnosed with extramammary Paget’s disease. Seven years after the initial diagnosis, multiple bone metastases were discovered, and he was started on oral administration of tegafur/gimeracil/oteracil. Two years after beginning the oral drug administration, the patient complained of dyspnea. A chest CT scan showed ground-glass opacity. Pulmonary artery blood cytology revealed carcinoma cells. He was diagnosed with pulmonary tumor thrombotic microangiopathy. At 9 days after the diagnosis, he died of circulatory and respiratory failure. The autopsy revealed microscopic metastatic tumor emboli in multiple pulmonary vessels with fibrin thrombus, which confirmed the earlier cytologic diagnosis. Observations in our case were consistent with the typical pattern of this pathology in the lung with multiple metastases. Pulmonary tumor thrombotic microangiopathy with a primary disease of cutaneous malignancy is extremely rare. Here, we report a rare case of pulmonary tumor thrombotic microangiopathy secondary to extramammary Paget’s disease with a literature review.

scholarly journals A Case Report of Familial Extramammary Paget's Disease in Female Siblings

2021 ◽  
pp. 176-183
Author(s):  
Thanachat Rutnumnoi ◽  
Charussri Leeyaphan
Keyword(s):  
Case Report ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Genetic Mutations ◽  
Extramammary Paget’S Disease ◽  
Perianal Area ◽  
Familial Form ◽  
Extramammary Paget's Disease

Extramammary Paget’s disease (EMPD) is a rare intraepithelial neoplasm that occurs in apocrine-bearing areas of skin. Most EMPD patients initially present with chronic pruritic eczematous lesions involving genitalia, perineum and perianal area. Familial form of EMPD is extremely rare. Several genetic mutations have been proposed but specific modes of inheritance are still unknown. This article reports two cases of familial extramammary Paget’s disease in female siblings.

Case of extramammary Paget’s disease causing pulmonary tumor embolism

2020 ◽  
Vol 47 (4) ◽  
Author(s):  
Yuma Waki ◽  
Yoshimasa Nobeyama ◽  
Tomohiro Ogawa ◽  
Osamu Fukuchi ◽  
Nei Fukazawa ◽  
...  
Keyword(s):  
Paget’S Disease ◽  
Paget's Disease ◽  
Extramammary Paget’S Disease ◽  
Tumor Embolism ◽  
Pulmonary Tumor ◽  
Extramammary Paget's Disease

Extramammary Paget’s disease associated with brain metastasis : a case report

Skin Cancer ◽  
2020 ◽  
Vol 35 (2) ◽  
pp. 71-75
Author(s):  
Naohisa ICHIKI ◽  
Hirofumi NIWA ◽  
Kanako MATSUYAMA ◽  
Takaaki ITAZU ◽  
Noriyuki NAKAYAMA ◽  
...  
Keyword(s):  
Case Report ◽  
Brain Metastasis ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Extramammary Paget’S Disease ◽  
Extramammary Paget's Disease

Extramammary Paget's disease arising from a burn scar of right forearm: An uncommon case report

Burns ◽  
2010 ◽  
Vol 36 (8) ◽  
pp. e145-e147 ◽  
Author(s):  
Daofeng Ben ◽  
Liu Liu ◽  
Bing Ma ◽  
Yongyan Li ◽  
Zhaofan Xia
Keyword(s):  
Case Report ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Extramammary Paget’S Disease ◽  
Burn Scar ◽  
Uncommon Case ◽  
Extramammary Paget's Disease

scholarly journals Extramammary Paget’s Disease in the Pubic Region: a Case Report

2013 ◽  
Vol 5 (4) ◽  
pp. 171-176
Author(s):  
Slobodan Stojanović ◽  
Nada Vučković ◽  
Pavle Jeremić ◽  
Biljana Jeremić
Keyword(s):  
Case Report ◽  
Private Practice ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Histopathological Analysis ◽  
Extramammary Paget’S Disease ◽  
Incisional Biopsy ◽  
Definite Diagnosis ◽  
Internal Organs ◽  
Extramammary Paget's Disease

Abstract The authors present a case of a patient with extramammary Paget’s disease in the pubic region treated by a dermatologist with a private practice for almost 4 years before incisional biopsy was performed. A thorough examination showed no evidence of malignancies of internal organs, whereas definite diagnosis was made by excision of the entire skin lesion and histopathological analysis. With regard to multiple criteria, findings in our patient were consistent with current literature data, but interestingly, the primary extramammary Paget’s disease has not spread into deeper tissues.

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