Effect of single‐nucleotide polymorphism in TERT promoter on follicular thyroid tumor development

2020 ◽  
Vol 70 (4) ◽  
pp. 210-216
Author(s):  
Tatsuya Hirokawa ◽  
Yuu Arimasu ◽  
Yoko Nakazato ◽  
Tomohiro Chiba ◽  
Masachika Fujiwara ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Tumor Development ◽  
Thyroid Tumor ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide ◽  
Tert Promoter

scholarly journals The prognostic impact of TERT promoter mutations in glioblastomas is modified by the rs2853669 single nucleotide polymorphism

2016 ◽  
Vol 139 (2) ◽  
pp. 414-423 ◽  
Author(s):  
Rui Batista ◽  
Adriana Cruvinel-Carloni ◽  
João Vinagre ◽  
Joana Peixoto ◽  
Telmo A. Catarino ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Prognostic Impact ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide ◽  
Tert Promoter ◽  
Tert Promoter Mutations ◽  
Promoter Mutations

UTILIZATION OF DNA MARKERS FOR EVALUATING AMYLOSE CONTENT OF GRAIN IN RICE

2013 ◽  
Vol 83 (5) ◽  
Author(s):  
Dương Thanh Thủy ◽  
Taiichiro Ookawa
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Amylose Content ◽  
Waxy Gene ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide ◽  
Branching Enzymes ◽  
Wx Gene ◽  
High Amylose ◽  
Suitable Marker ◽  
Granule Bound Starch Synthase

The sensory and functional properties of rice are predominantly associated with its amylose content. Granule-bound starch synthase (GBSS) encoded by the Waxy (Wx) gene determines the synthesis of amylose, while starch branching enzymes encoded by Sbe genes are involved in the formation of amylopectin. Some studies have demonstrated that Wx gene is the major controller of amylose content but there are one or more modifying genes affecting the amylose content. Three markers,  microsatellite, Single – nucleotide – polymorphism (G/T SNP) in Wx gene and Single – nucleotide – polymorphism (T/C SNP) in Sbe1 gene, were tested for their association with amylose content using sixty-nine  rice accessions from twenty countries. Of the three markers, two markers in Wx gene are significantly associated with amylose content. The combination of two markers in Wx gene (haplotypes) explained 83.8% of the variation in amylose content and discriminated the three market classes of glutinous, low, intermediate and high amylose content of rice from each other. And T/C SNP in Sbe1 locus was not a suitable marker for amylose content. Keywords: marker, amylose content, Waxy gene.

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