Differences between gastric signet-ring cell carcinoma and poorly differentiated adenocarcinoma: A comparison of histopathologic features determined by mucin core protein and trefoil factor family peptide immunohistochemistry

2017 ◽  
Vol 67 (8) ◽  
pp. 398-403 ◽  
Author(s):  
Ai Fujimoto ◽  
Yukio Ishikawa ◽  
Toshiharu Ishii ◽  
Akihiro Yamada ◽  
Yoshinori Igarashi ◽  
...  
Keyword(s):  
Core Protein ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Trefoil Factor ◽  
Poorly Differentiated Adenocarcinoma ◽  
Signet Ring ◽  
Mucin Core Protein ◽  
Poorly Differentiated ◽  
Trefoil Factor Family ◽  
Ring Cell

scholarly journals A Case of Poorly Differentiated Adenocarcinoma with Signet Ring Cell Carcinoma of the Duodenal Bulb: A Case Report

2017 ◽  
Vol 102 (3-4) ◽  
pp. 141-144 ◽  
Author(s):  
Kosuke Hirano ◽  
Yukinori Yamagata ◽  
Teppei Tatsuoka ◽  
Yawara Kubota ◽  
Kazuyuki Saito ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Rare Case ◽  
Case Reports ◽  
Duodenal Bulb ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Poorly Differentiated Adenocarcinoma ◽  
Signet Ring ◽  
Poorly Differentiated ◽  
Ring Cell

Duodenal cancers are rare. Histopathologically, most duodenal cancers are adenocarcinoma. Signet ring cell carcinoma (SRCC) is a rare tumor more commonly found in the stomach than at other sites in the digestive tract. SRCC is extremely uncommon in the duodenum, with most of these tumors occurring in the ampulla. Until now, there are few case reports of duodenal cancers with SRCC. To accumulate case reports, we report a rare case of nonampullary duodenal bulb SRCC. A 74-year-old man was admitted to our hospital with melena. Esophagogastroduodenoscopy (EGD) showed a duodenal bulb ulcer. He was treated with a proton pump inhibitor. However, 1 month later, he was readmitted to our hospital with epigastric pain and nausea. A second EGD examination showed an ulcer at the duodenal bulb. Biopsies taken from the ulcer showed SRCC. Distal gastrectomy and duodenal bulb resection were performed. Histologic examination of the specimen showed a type 4 lesion located from the duodenal bulb to the pyloric antrum. The tumor was composed of poorly differentiated adenocarcinoma (por) with SRCC. The distal margin of the duodenal bulb was invaded with tumor. Therefore, pancreatoduodenectomy was performed. One year after the initial operation, he is alive and had no relapse. We described a rare case of por with SRCC of the duodenal bulb. It is important to bear in mind that an ulcer following an abnormal clinical course should be biopsied, and we have to select a suitable operation in cases of duodenal bulb cancer.

Poorly Differentiated Adenocarcinoma with Signet-Ring Cell Carcinoma in a Hyperplastic Polyp of the Stomach: Report of a Case

Surgery Today ◽  
2007 ◽  
Vol 37 (10) ◽  
pp. 901-904 ◽  
Author(s):  
Hiroshi Hirano ◽  
Toshimi Yoshida ◽  
Hitoshi Yoshimura ◽  
Masato Fukuoka ◽  
Eriko Ohkubo ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Hyperplastic Polyp ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Poorly Differentiated Adenocarcinoma ◽  
Signet Ring ◽  
Poorly Differentiated ◽  
Ring Cell
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