Clonality analysis performed using human androgen receptor assay in a rare case of undifferentiated thymic carcinoma coexisting with type AB thymoma

2016 ◽  
Vol 66 (7) ◽  
pp. 398-403 ◽  
Author(s):  
Fumi Karino ◽  
Tomoyuki Yokose ◽  
Shoichi Matsukuma ◽  
Yohei Miyagi ◽  
Shuji Murakami ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Rare Case ◽  
Thymic Carcinoma ◽  
Receptor Assay ◽  
Clonality Analysis ◽  
Type Ab ◽  
Human Androgen Receptor ◽  
Type Ab Thymoma

Large cell neuroendocrine thymic carcinoma coexisting within large who type AB thymoma

2006 ◽  
Vol 54 (6) ◽  
pp. 256-259 ◽  
Author(s):  
Yoko Nagata ◽  
Kiyoshi Ohno ◽  
Tomoki Utsumi ◽  
Yoshiaki Sasaki ◽  
Yuko Suzuki
Keyword(s):  
Thymic Carcinoma ◽  
Large Cell ◽  
Type Ab ◽  
Type Ab Thymoma

scholarly journals Clonality analysis of giant cell lesions of the jaws

2010 ◽  
Vol 21 (4) ◽  
pp. 361-364 ◽  
Author(s):  
Fabrício Rezende Amaral ◽  
Carolina Cavaliéri Gomes ◽  
Carla Silveira Oliveira ◽  
Paulo Eduardo Alencar de Souza ◽  
Ricardo Santiago Gomez
Keyword(s):  
Androgen Receptor ◽  
Giant Cell ◽  
Molecular Mechanisms ◽  
Genetic Mechanism ◽  
Receptor Locus ◽  
Clonality Analysis ◽  
Human Androgen Receptor ◽  
Humara Assay

Despite the importance of clonality to understand the pathogenesis and progression of tumors, it has not been investigated yet in giant cell lesions of the jaws. The aim of this study was to analyze the clonality of peripheral giant cell lesions (PGCL) and central giant cell lesions (CGCL) of the jaws. Six samples of PGCL and 5 samples of CGCL were analyzed in this study using the polymorphic human androgen receptor locus (HUMARA) assay. Three out of the 5 samples of the CGCL and 3 out of 6 samples of PGCL exhibited a monoclonal pattern. Our findings demonstrate that some giant cell lesions of the jaws are clonal, which indicate that these lesions may have a common genetic mechanism of development. Further studies are necessary to better elucidate the molecular mechanisms involved in the pathogenesis of such lesions.

Primary thymic adenocarcinoma coexisting with type AB thymoma: a rare case with long-term survival

2010 ◽  
Vol 58 (9) ◽  
pp. 488-492 ◽  
Author(s):  
Yasuko Hosaka ◽  
Masanori Tsuchida ◽  
Hajime Umezu ◽  
Tadaaki Eimoto ◽  
Takehisa Hashimoto ◽  
...  
Keyword(s):  
Rare Case ◽  
Term Survival ◽  
Long Term Survival ◽  
Thymic Adenocarcinoma ◽  
Type Ab ◽  
Type Ab Thymoma
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