Is ultraviolet radiation avoidance affecting bone health in melanoma patients?

Author(s):  
Lodovica Gariazzo ◽  
Giulia Gasparini ◽  
Andrea Casabella ◽  
Luca Carmisciano ◽  
Andrea Clapasson ◽  
...  
2016 ◽  
Vol 38 (1) ◽  
pp. 16-26 ◽  
Author(s):  
Erin P. Overholt ◽  
Kevin C. Rose ◽  
Craig E. Williamson ◽  
Janet M. Fischer ◽  
Nathalie A. Cabrol

2019 ◽  
Vol 184 (Supplement_1) ◽  
pp. 506-510
Author(s):  
Michael G Kimlin ◽  
Pip Youl ◽  
Peter Baade ◽  
Sheree Rye ◽  
Alison Brodie

Abstract Objectives This study will assess the relationship between vitamin D concentration at melanoma diagnosis and melanoma tumor characteristics, in individuals in a high ultraviolet radiation (UVR) environment. Methods We aim to recruit 600 recently diagnosed melanoma patients from Queensland, Australia, a high UVR location with one of the world’s highest melanoma incidence rates. Patients are recruited through general practitioner, skin cancer specialist, dermatological and hospital-based practices. As close as possible to diagnosis, participants provide a blood sample for vitamin D analysis and have their sun exposure/sun protection behavior, melanoma risk factors and dietary vitamin D intake assessed by questionnaire and phone interview. Details of tumor pathology, including tumor level, thickness, and ulceration, are abstracted from cancer registry records. Here, we describe the study methods and present preliminary findings from early participants. Results As of December 2017, we have recruited 128 participants (48% male, mean age 60.2 years, mean Breslow thickness 0.63 mm). Conclusions When complete, this study will give insights into the association between vitamin D at diagnosis and melanoma tumor characteristics whilst adjusting for recent sun exposure and sun protection use. This study may impact military sun exposure and nutrition policies as vitamin D may play a role in melanomagenesis.


2019 ◽  
Vol 651 ◽  
pp. 3070-3078 ◽  
Author(s):  
Christina Pasparakis ◽  
Yadong Wang ◽  
John D. Stieglitz ◽  
Daniel D. Benetti ◽  
Martin Grosell

Author(s):  
William J. Baxter

In this form of electron microscopy, photoelectrons emitted from a metal by ultraviolet radiation are accelerated and imaged onto a fluorescent screen by conventional electron optics. image contrast is determined by spatial variations in the intensity of the photoemission. The dominant source of contrast is due to changes in the photoelectric work function, between surfaces of different crystalline orientation, or different chemical composition. Topographical variations produce a relatively weak contrast due to shadowing and edge effects.Since the photoelectrons originate from the surface layers (e.g. ∼5-10 nm for metals), photoelectron microscopy is surface sensitive. Thus to see the microstructure of a metal the thin layer (∼3 nm) of surface oxide must be removed, either by ion bombardment or by thermal decomposition in the vacuum of the microscope.


2006 ◽  
Vol 175 (4S) ◽  
pp. 260-260
Author(s):  
Nicholas J. Rukin ◽  
Samuel J. Moon ◽  
Dhaval Bodiwala ◽  
Christopher J. Luscombe ◽  
Mark F. Saxby ◽  
...  

2005 ◽  
Vol 38 (3) ◽  
pp. 22
Author(s):  
TIMOTHY F. KIRN
Keyword(s):  

2007 ◽  
Vol 40 (23) ◽  
pp. 24
Author(s):  
GREG MUIRHEAD
Keyword(s):  

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