Narrowband ultraviolet B phototherapy starting and incremental dose in patients with psoriasis: comparison of percentage dose and fixed dose protocols

2014 ◽  
Vol 31 (2) ◽  
pp. 90-97 ◽  
Author(s):  
Nehir Parlak ◽  
Nihal Kundakci ◽  
Adem Parlak ◽  
Bengu Nisa Akay
Keyword(s):  
Ultraviolet B ◽  
Fixed Dose ◽  
Incremental Dose

scholarly journals Biochemical Outcome of Repeated Radioactive Iodine Therapy in Patients with Primary Hyperthyroidism– Follow Up of a Decade

2021 ◽  
Vol 22 (2) ◽  
pp. 119-124
Author(s):  
Sharmin Reza ◽  
Azmal Kabir Sarker ◽  
Farhana Haque ◽  
Mohammed Mehedi Al Zahid Bhuiyan ◽  
Simoon Salekin ◽  
...  
Keyword(s):  
Radioactive Iodine ◽  
Nodular Goiter ◽  
Descriptive Statistics ◽  
Fixed Dose ◽  
Radioactive Iodine Therapy ◽  
Clinical Reality ◽  
Demographic Traits ◽  
Primary Hyperthyroidism ◽  
Incremental Dose

Background: Whileradioactive iodine therapy (RAIT) in patients with primary hyperthyroidism results in euthyreosis or hypothyreosis, requirement of repeated therapy in a proportion of patients is a clinical reality. This study describesbiochemical outcomeof patients requiring repeated RAIT and the dose profiles across the demographic traits. Patients and Methods: The study retrospectively included the patients who underwent RAIT for Primary hyperthyroidism from January to December of 2006, using a modified fixed dose protocol following an institutional guideline which was adopted as the national guideline in 2007. Persistence of biochemical features of hyperthyroidism six months after RAIT was an indication for repeated therapy. Follow up data of eligible patients till December of 2016 was included in the descriptive statistics. Results: One, Two, three and four instances of RAIT were given to 83%, 14%, 2% and ≤ 1% of patients resulting in hypothyroidism to 58%, 67%, 67% and 100% of patients after each instance of therapy with incremental dose. Apparently more females than males ended up as biochemically hypothyroid, though not significant (OR 1.15, p=0.56).Younger females became significantly hypothyroid (p = 0.03).Patients with euthyroid outcome received higher dose-1of RAIT (P=0.007) which was found significant in females (p=0.005), in patients with Graves’ disease (GD) (p=0.018) and in patients receiving two instances of RAIT (p=0.03). Among the patients with GD, Single Toxic Nodule (STN) and Multi-Nodular Goiter (MNG), the proportion of hypothyroid outcome were 61%, 67% and 35%, at ten years following first dose. GD and STN required RAIT for up to four instances.MNG received an apparently higher mean of dose -1 and apparently less steep increment of doses, in comparison to GD and STN. Conclusion: Thisobservationof patient outcome over a decade was a scope to compare the mentioned guideline’s performance with the targets set by influential guidelines and recent reports around the globe. Bangladesh J. Nuclear Med. 22(2): 119-124, Jul 2019

Topical application of solubilized Reseda luteola extract inhibits ultraviolet B-induced inflammation in human volunteers in vivo

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
F Casetti ◽  
W Jung ◽  
U Wölfle ◽  
J Reuter ◽  
K Neumann ◽  
...  
Keyword(s):  
Topical Application ◽  
Ultraviolet B ◽  
Human Volunteers

Efficacy and safety of aclidinium/formoterol fixed-dose combination in patients with COPD, stratified by ICS use

Pneumologie ◽  
2016 ◽  
Vol 70 (S 01) ◽  
Author(s):  
ED Bateman ◽  
K Chapman ◽  
S Rennard ◽  
L Rekeda ◽  
M Moya ◽  
...  
Keyword(s):  
Fixed Dose Combination ◽  
Fixed Dose ◽  
Efficacy And Safety ◽  
Dose Combination

White clover sensitivity to UV-B radiation - biochemical relationships and interaction with drought

2003 ◽  
pp. 273-277
Author(s):  
R.W. Hofmann ◽  
B.D. Campbell ◽  
E.E. Swinny ◽  
S.J. Bloor ◽  
K.R. Markham ◽  
...  
Keyword(s):  
New Zealand ◽  
White Clover ◽  
Ultraviolet B ◽  
Summer Drought ◽  
Stress Protection ◽  
Trade Offs ◽  
Population Comparisons ◽  
Potential Benefits ◽  
Quercetin Glycosides ◽  
Balance Trade

During summertime in New Zealand, white clover experiences high levels of ultraviolet-B (UV-B) radiation. This frequently coincides with periods of summer drought. We investigated responses to UV-B and to the combination of UV-B and drought in various white clover populations, including New Zealand cultivars and ecotypes as well as overseas germplasm. The results were obtained under controlled environmental conditions in three independent trials. Overall, white clover growth was reduced by UV-B. The population comparisons indicated that low growth rate and adaptation to other forms of stress may be related to UV-B tolerance under well-watered conditions, but not during extended periods of drought. Flavonoid pigments that are involved in stress protection were strongly increased under UV-B and were further enhanced in the combination of UV-B and drought. The responses among these flavonoids were highly specific, with more pronounced UV-B-induced increases in quercetin glycosides, compared to their closely related kaempferol counterparts. UV-B toler ance of the less productive white clover populations was linked to the accumulation of quercetin compounds. In conclusion, these studies suggest (i) that slow-growing white clover ecotypes adapted to other stresses have higher capacity for biochemical acclimation to UV-B under well-watered conditions and (ii) that these biochemical attributes may also contribute to decreased UV-B sensitivity across white clover populations under drought. The findings alert plant breeders to potential benefits of selecting productive germplasm for high levels of specific flavonoids to balance trade-offs between plant productivity and stress tolerance. Keywords: Drought, flavonoids, genetic variation, HPLC, kaempferol, quercetin, str ess, Trifolium repens L., ultraviolet-B, white clover

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