scholarly journals The Discovery, Development, and Demonstration of Three Caged Compounds

2021 ◽  
Author(s):  
Mark G. Steinmetz ◽  
Richard S. Givens
Keyword(s):  
Caged Compounds

From One-Photon to Two-Photon Probes: “Caged” Compounds, Actuators, and Photoswitches

2013 ◽  
Vol 52 (17) ◽  
pp. 4526-4537 ◽  
Author(s):  
Guillaume Bort ◽  
Thibault Gallavardin ◽  
David Ogden ◽  
Peter I. Dalko
Keyword(s):  
Caged Compounds ◽  
Two Photon

A low-cost UV laser for flash photolysis of caged compounds

1996 ◽  
Vol 66 (1) ◽  
pp. 47-54 ◽  
Author(s):  
Florian Engert ◽  
Gerhard G. Paulus ◽  
Tobias Bonhoeffer
Keyword(s):  
Flash Photolysis ◽  
Low Cost ◽  
Uv Laser ◽  
Caged Compounds

Controlling Cell Chemistry with Caged Compounds

1993 ◽  
Vol 55 (1) ◽  
pp. 755-784 ◽  
Author(s):  
S R Adams ◽  
R Y Tsien
Keyword(s):  
Caged Compounds

scholarly journals Exogenous control over intracellular acidification: Enhancement via proton caged compounds coupled to gold nanoparticles and an alternative pathway with DMSO

Data in Brief ◽  
2016 ◽  
Vol 6 ◽  
pp. 745-749 ◽  
Author(s):  
Marilena Carbone ◽  
Gianfranco Sabbatella ◽  
Simonetta Antonaroli ◽  
Hynd Remita ◽  
Viviana Orlando ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Alternative Pathway ◽  
Intracellular Acidification ◽  
Caged Compounds ◽  
Exogenous Control

scholarly journals Cross-talk between Native Plasmalemmal Na+/Ca2+Exchanger and Inositol 1,4,5-Trisphosphate-sensitive Ca2+Internal Store inXenopusOocytes

2004 ◽  
Vol 279 (50) ◽  
pp. 52414-52424 ◽  
Author(s):  
Luisa M. Solís-Garrido ◽  
Antonio J. Pintado ◽  
Eva Andrés-Mateos ◽  
María Figueroa ◽  
Carlos Matute ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Surface Membrane ◽  
Rabbit Serum ◽  
Caged Compounds ◽  
Reverse Transcription Pcr ◽  
Inositol 1,4,5 Trisphosphate ◽  
Intracellular Ca ◽  
Functional Consequences ◽  
Extracellular Sodium ◽  
Cortical Endoplasmic Reticulum

Because the presence of a native plasmalemmal Na+/Ca2+exchange (NCX) activity inXenopus laevisoocytes remains controversial, its possible functional role in these cells is poorly understood. Here, in experiments on control oocytes and oocytes overexpressing a cloned NCX1 cardiac protein, confocal microscopy combined with electrophysiological techniques reveal that these cells express an endogenous NCX protein forming a functional microdomain with inositol 1,4,5-trisphosphate receptors (InsP3R) that controls intracellular Ca2+in a restricted subplasmalemmal space. The following data obtained in control denuded oocytes are consistent with this view: (i) reverse transcription-PCR revealed that the oocyte expresses two transcripts for the NCX1 and NCX3 isoforms; (ii) immunofluorescence experiments showed that native NCX1 and InsP3Rs are largely codistributed in discrete areas of the plasma membrane in close apposition to the cortical endoplasmic reticulum shell; (iii) when stimulated by rabbit serum, which elevates intracellular Ca2+mediated by InsP3, voltage-clamped oocytes display a large and transient inward Ca2+-activated chloride current, ICl(Ca), as a result of the Ca2+rise at the inner surface membrane; (iv) this current is significantly enhanced by KB-R7943 and by an extracellular sodium-depleted medium, two maneuvers that prevent “Ca2+extrusion” via NCX; and (v) blocking NCX enhanced the ICl(Ca)elicited by InsP3but not by Ca2+photolysis in oocytes injected with the respective caged compounds. Moreover, overexpression of cardiac NCX1, confirmed by confocal microscopy, has functional consequences for the “Ca2+influx” but not for the serum-elicited “Ca2+efflux” mode of basal exchange activity and does not alter the number of endogenous NCX/InsP3Rs colocalization sites. Our results suggest that native NCX, because of its strategic position, may regulate InsP3-mediated Ca2+signaling during the early phases of oocyte maturation and/or fertilization, and furthermore foreign cardiac protein is excluded from the Ca2+microdomains surrounding the native NCX/InsP3Rs complex in the oocyte.

[12] Fourier transform infrared photolysis studies of caged compounds

1998 ◽  
pp. 223-245 ◽  
Author(s):  
Valentin Cepus ◽  
Carola Ulbrich ◽  
Christoph Allin ◽  
Agnes Troullier ◽  
Klaus Gerwert
Keyword(s):  
Fourier Transform ◽  
Fourier Transform Infrared ◽  
Caged Compounds
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