scholarly journals Hormonal Regulation of the Repair of UV Photoproducts in Melanocytes by the Melanocortin Signaling Axis

2016 ◽  
Vol 93 (1) ◽  
pp. 245-258 ◽  
Author(s):  
Stuart G. Jarrett ◽  
John A. D'Orazio
Keyword(s):  
Hormonal Regulation ◽  
Signaling Axis ◽  
Melanocortin Signaling ◽  
Uv Photoproducts

GENE ACTIVATION IN MAMMARY CELLS

1972 ◽  
Vol 71 (2_Suppla) ◽  
pp. S346-S368 ◽  
Author(s):  
Roger W. Turkington ◽  
Nobuyuki Kadohama
Keyword(s):  
Cell Differentiation ◽  
Gene Transcription ◽  
Hormonal Regulation ◽  
Gene Activation ◽  
Milk Proteins ◽  
Mouse Mammary Gland ◽  
Nuclear Proteins ◽  
Mammary Cells ◽  
Alveolar Cells ◽  
Mammary Cell

ABSTRACT Hormonal activation of gene transcription has been studied in a model system, the mouse mammary gland in organ culture. Transcriptive activity is stimulated in mammary stem cells by insulin, and in mammary alveolar cells by prolactin and insulin. Studies on the template requirement for expression of the genes for milk proteins demonstrate that DNA methylation has an obligatory dependence upon DNA synthesis, but is otherwise independent from hormonal regulation of mammary cell differentiation. Incorporation of 5-bromo-2′deoxyuridine into DNA selectively inhibits expression of the genes for specific milk proteins. Undifferentiated mammary cells activate the synthesis of specific acidic nuclear proteins when stimulated by insulin. Several of these induced acidic nuclear proteins are undetectable in unstimulated undifferentiated cells, but appear to be characteristic components of the nuclei of differentiated cells. These results indicate that mammary cell differentiation is associated with a change in acidic nuclear proteins, and they provide evidence to support the concept that acidic nuclear proteins may be involved in the regulation of gene transcription and of mammary cell differentiation.

Modern approaches to the prevention and treatment of alterations in reproductive health in women with somatoform disorders and autonomic homeostasis

2016 ◽  
pp. 98-101
Author(s):  
Vl.V. Podolsky ◽  
◽  
V.V. Podolsky ◽  
Keyword(s):  
Reproductive Health ◽  
Hormonal Regulation ◽  
Preventive Measures ◽  
Somatoform Disorders ◽  
Emotional Health ◽  
Uterine Fibroids ◽  
Reproductive Function ◽  
Epidemiological Studies ◽  
Prevention And Treatment ◽  
Artificial Abortion

The objective: the developing of a system of preventive measures and principles of pregravid preparation for women with somatoform disorders and violation of autonomic homeostasis (VAH), in which observed changes in reproductive health (CRH) in the shape of states after undergoing artificial abortion, infertility and uterine fibroids. Patients and methods. Conducted clinical and epidemiological studies in the population of women of fertile age (WFA) allowed identifying for further examination of women with CRH in the form of state after undergoing artificial abortion, infertility and uterine fibroids in women with VAH. Further women were examined, in particular the conducted clinical and instrumental methods of research; determined the state of autonomic homeostasis and psycho emotional health of the biotopes of the organism, immunity; analyzed the hormonal regulation of the menstrual cycle; performed genetic studies and determined the morphofunctional state of reproductive system. Results. The most frequent complications during pregnancy in women who had CRH in history in the form of abortions, infertility and uterine fibroids and in the background of the PAF, there was a threat of interruption of pregnancy (often in I and II trimester – 56%) and preterm delivery (21%). The study of the catamnesis of further reproductive health found that in the case of well-conducted therapeutic measures in women undergoing artificial abortion, had infertility and uterine leiomyoma in the background of VAH, restore reproductive function, and in 82% of cases occurred a pregnancy. Conclusion. The the provided study of reproductive health, and state of various organs and systems of fertile aged women with somatoform disorders and violations of the autonomic homeostasis allowed to develop preventive measures for these women and pregravid preparation with the inclusion to the therapy Magnesium and vitamins (Magne-В6®). Key words: somatoform disorders, violation of autonomic homeostasis, changes in reproductive health, prevention and treatment, women of fertile age, Magne-В6®.

Hormonal regulation of calcium homeostasis in two breeds of dogs during growth at different rates

2003 ◽  
Vol 81 (6) ◽  
pp. 1568 ◽  
Author(s):  
M. A. Tryfonidou ◽  
M. S. Holl ◽  
M. Vastenburg ◽  
M. A. Oosterlaken-Dijksterhuis ◽  
D. H. Birkenhäger-Frenkel ◽  
...  
Keyword(s):  
Calcium Homeostasis ◽  
Hormonal Regulation

FEATURES OF THE WINTER WHITE CABBAGE VARIETIES GENERATIVE DEVELOPMENT

1970 ◽  
pp. 38-40
Author(s):  
R. E. Kazakhmedov ◽  
М. А Magomedova
Keyword(s):  
Hormonal Regulation ◽  
F1 Hybrids ◽  
Vegetable Crops ◽  
Stem Extension ◽  
Market Competitiveness ◽  
White Cabbage ◽  
Environmentally Safe ◽  
Selection Tasks ◽  
High Yielding Varieties ◽  
High Yields

One of the modern selection tasks in vegetable growing is quality products improving, obtaining high yields of environmentally safe wide assortment vegetables. To the new varieties of vegetable crops including winter white cabbage are specified new requirements such as market competitiveness, resistance to unfavorable environmental conditions, heat resistance of the varieties and F1 hybrids. The article is shown investigation results about studies of exogenous treatment by solutions on the base of physiologically active compounds of hormonal nature on the started process of stem extension stage activation and flowering of winter white cabbage plants. For the first time in the Dagestan conditions has been studied the possibility of hormonal regulation of the premature stem extension stage and flowering prevention of winter white cabbage after the initiation of natural induction. In our studies with an early planting there are not more than 20% of blooming plants, most varieties showed a high propensity to premature stem extension stage and flowering. The possibility of the hormonal exogenous regulation of the unfavorable winter white cabbage flowering has been revealed. The most pronounced effect on the transition to stem extension stage and flowering were provided by auxin nature preparations. In particular, treatment with NAS at a dose of 5 mg / l significantly reduced the number of blossom plants, krezatsin (50 mg / l) had a similar effect, but it was less pronounced. The use of cabbage in winter crops makes it possible to obtain two or three yields per year from the same area. Creation and introduction into production of promising and high-yielding varieties and hybrids will allow increasing production and reducing its cost.

State of hormonal regulation in experimental animals exposed to noise and vibration

2020 ◽  
pp. 680-681
Author(s):  
A. V. Lizarev ◽  
V. A. Pankov
Keyword(s):  
Blood Plasma ◽  
Hormonal Regulation ◽  
Adrenocorticotropic Hormone ◽  
Vibration Exposure ◽  
Noise And Vibration ◽  
Experimental Animals ◽  
In Blood Plasma

When exposed to noise and vibration in experimental animals there was a decrease in the content of threeiodinethyronine, thyroxin and adrenocorticotropic hormone in blood plasma after 15 and 30 days of experience. An increase in loads led to an increase in the level of threeiodinethyronine and thyroxin under vibration exposure and was normalized with noise. The content of adrenocorticotropic hormone leveled in both cases.

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