Gp91phox-derived Reactive Oxygen Species/Urocortin 2/Corticotropin-releasing Hormone Receptor Type 2 Play an Important Role in Long-term Ultraviolet A Eye Irradiation-induced Photoaging

2015 ◽  
Vol 92 (1) ◽  
pp. 180-186 ◽  
Author(s):  
Keiichi Hiramoto ◽  
Yurika Yamate
Keyword(s):  
Reactive Oxygen Species ◽  
Hormone Receptor ◽  
Reactive Oxygen ◽  
Receptor Type ◽  
Oxygen Species ◽  
Corticotropin Releasing Hormone ◽  
Ultraviolet A ◽  
Releasing Hormone

scholarly journals Physiological Roles of Corticotropin-Releasing Hormone Receptor Type 2.

2001 ◽  
Vol 48 (1) ◽  
pp. 1-9 ◽  
Author(s):  
KOZO HASHIMOTO ◽  
SHINYA MAKINO ◽  
KOICHI ASABA ◽  
MITSURU NISHIYAMA
Keyword(s):  
Hormone Receptor ◽  
Receptor Type ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone

Urocortin and Corticotropin-Releasing Hormone Receptor Type 2 Expression in the Human Gallbladder

2005 ◽  
Vol 82 (3-4) ◽  
pp. 177-184 ◽  
Author(s):  
Ekaterini Chatzaki ◽  
Christoforos Euthymiadis ◽  
Sofia Kyriaki ◽  
Maria Lambropoulou ◽  
Alexandra Tsaroucha ◽  
...  
Keyword(s):  
Hormone Receptor ◽  
Receptor Type ◽  
Corticotropin Releasing Hormone ◽  
Human Gallbladder ◽  
Releasing Hormone

Modulation of corticotropin-releasing hormone receptor type 2 mRNA expression by CRH deficiency or stress in the mouse heart

2003 ◽  
Vol 115 (2) ◽  
pp. 131-138 ◽  
Author(s):  
Hossein Pournajafi Nazarloo ◽  
Yasushi Tanaka ◽  
Maria Dorobantu ◽  
Kozo Hashimoto
Keyword(s):  
Mrna Expression ◽  
Hormone Receptor ◽  
Receptor Type ◽  
Mouse Heart ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone

Expression of Corticotropin-Releasing Hormone Receptor Type 1 and Type 2 in Human Pregnant Myometrium

2007 ◽  
Vol 14 (6) ◽  
pp. 568-577 ◽  
Author(s):  
Dan Jin ◽  
Ping He ◽  
Xingji You ◽  
Xiaoyan Zhu ◽  
Ling Dai ◽  
...  
Keyword(s):  
Hormone Receptor ◽  
Receptor Type ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone

scholarly journals Urocortin 3 Modulates Social Discrimination Abilities via Corticotropin-Releasing Hormone Receptor Type 2

2010 ◽  
Vol 30 (27) ◽  
pp. 9103-9116 ◽  
Author(s):  
J. M. Deussing ◽  
J. Breu ◽  
C. Kuhne ◽  
M. Kallnik ◽  
M. Bunck ◽  
...  
Keyword(s):  
Hormone Receptor ◽  
Receptor Type ◽  
Corticotropin Releasing Hormone ◽  
Social Discrimination ◽  
Releasing Hormone ◽  
Urocortin 3

Dissecting the role of Corticotropin-releasing hormone receptor type 1 in Alzheimer's Disease

2011 ◽  
Vol 44 (06) ◽  
Author(s):  
K Lerche ◽  
M Willem ◽  
K Kleinknecht ◽  
C Romberg ◽  
U Konietzko ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Hormone Receptor ◽  
Receptor Type ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone

scholarly journals Limited Mitochondrial Capacity of Visceral Versus Subcutaneous White Adipocytes in Male C57BL/6N Mice

Endocrinology ◽  
2015 ◽  
Vol 156 (3) ◽  
pp. 923-933 ◽  
Author(s):  
Theresa Schöttl ◽  
Lisa Kappler ◽  
Katharina Braun ◽  
Tobias Fromme ◽  
Martin Klingenspor
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen ◽  
Mitochondrial Respiratory Chain ◽  
Metabolic Risk ◽  
Oxygen Species ◽  
White Adipocyte ◽  
White Adipocytes ◽  
Fat Depot ◽  
Mitochondrial Capacity

Abstract Accumulation of visceral fat is associated with metabolic risk whereas excessive amounts of peripheral fat are considered less problematic. At the same time, altered white adipocyte mitochondrial bioenergetics has been implicated in the pathogenesis of insulin resistance and type 2 diabetes. We therefore investigated whether the metabolic risk of visceral vs peripheral fat coincides with a difference in mitochondrial capacity of white adipocytes. We assessed bioenergetic parameters of subcutaneous inguinal and visceral epididymal white adipocytes from male C57BL/6N mice employing a comprehensive respirometry setup of intact and permeabilized adipocytes as well as isolated mitochondria. Inguinal adipocytes clearly featured a higher respiratory capacity attributable to increased mitochondrial respiratory chain content compared with epididymal adipocytes. The lower capacity of mitochondria from epididymal adipocytes was accompanied by an increased generation of reactive oxygen species per oxygen consumed. Feeding a high-fat diet (HFD) for 1 week reduced white adipocyte mitochondrial capacity, with stronger effects in epididymal when compared with inguinal adipocytes. This was accompanied by impaired body glucose homeostasis. Therefore, the limited bioenergetic performance combined with the proportionally higher generation of reactive oxygen species of visceral adipocytes could be seen as a candidate mechanism mediating the elevated metabolic risk associated with this fat depot.

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