Response to Mr. Fluegge's Comment on Our Paper: “Endogenous Retinoic Acid Required to Maintain the Epidermis Following Ultraviolet Light Exposure in SKH-1 Hairless Mice” by Katherine L. Gresselet al., Photochemistry & Photobiology DOI: 10.1111/php.12441

2015 ◽  
Vol 91 (5) ◽  
pp. 1249-1250 ◽  
Author(s):  
Helen B. Everts
2015 ◽  
Vol 91 (4) ◽  
pp. 901-908 ◽  
Author(s):  
Katherine L. Gressel ◽  
F. Jason Duncan ◽  
Tatiana M. Oberyszyn ◽  
Krista M. La Perle ◽  
Helen B. Everts

Planta ◽  
2003 ◽  
Vol 217 (3) ◽  
pp. 457-465 ◽  
Author(s):  
Tanja Marwedel ◽  
Toyotaka Ishibashi ◽  
Ren� Lorbiecke ◽  
Silke Jacob ◽  
Kengo Sakaguchi ◽  
...  

1995 ◽  
Vol 74 (5) ◽  
pp. 493-498 ◽  
Author(s):  
Mark W. Beatty ◽  
Gordon K. Mahanna ◽  
Kurt Dick ◽  
Wenyi Jia

Endocrinology ◽  
2008 ◽  
Vol 149 (12) ◽  
pp. 6336-6342 ◽  
Author(s):  
Wenqiang Pang ◽  
Chunying Li ◽  
Yue Zhao ◽  
Shiming Wang ◽  
Wei Dong ◽  
...  

Environmental light is involved in the regulation of photochemical reaction in mouse retina. It remains unclear whether light-mediated increase in all-trans retinoic acid (ATRA) synthesis in retina will result in altering the circulatory levels of ATRA and regulating downstream gene expression and physiological function. Here we showed circulatory levels of ATRA decreased in mice under constant darkness and elevated by light exposure. Fat gene pancreatic lipase-related protein 2 (mPlrp2) and its partner procolipase (mClps), but not hepatic lipase (mHl), activated in livers for responding to lack of light illuminating. Light-triggered alterations in circulatory ATRA levels regulated ecto-5′-nucleotidase gene expression by retinoic acid receptor retinoic acid receptor-α and modulated 5′-AMP levels in blood and were associated with mPlrp2 and mClps expression in the livers. Mice deficient in adenosine receptors displayed mPlrp2 and mClps expression in livers under 12-h light, 12-h dark cycles. Caffeine blocked adenosine receptors and induced hepatic mPlrp2 and mClps expression in wild-type mice. Mice activated in hepatic mPlrp2 and mClps expression lowered hepatic and serum lipid levels and markedly elevated circulatory levels of all-trans retinol. Our results suggest environmental light influence hepatic lipid homeostasis by light-modulated retinoic acid signaling associated with mPlrp2 and mClps gene expression in livers.


1995 ◽  
Vol 10 (2) ◽  
pp. 139-144 ◽  
Author(s):  
Yumiko Takahashi ◽  
Osamu Ishikawa ◽  
Katsuyuki Okada ◽  
Kazunori Ohnishi ◽  
Yoshiki Miyachi

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