scholarly journals Why ‘Swampman’ Would Not Even Get as Far as Thinking it Was Davidson: On the Spatio‐temporal Basis of Davidson's Conjuring Trick

2019 ◽  
Vol 42 (4) ◽  
pp. 350-366
Author(s):  
Rupert Read ◽  
Bo Allesøe
Keyword(s):  
Spatio Temporal ◽  
Temporal Basis

scholarly journals Distribution and abundance of Citharus linguatula, Lepidorhombus boscii (Risso, 1810) and Solea vulgaris, (Osteichthyes, Pleuronectiformes) in the Mediterranean Sea

2002 ◽  
Vol 66 (S2) ◽  
pp. 83 ◽  
Author(s):  
Paolo Sartor ◽  
Mario Sbrana ◽  
Nicola Ungaro ◽  
Chiara A. Marano ◽  
Corrado Piccinetti ◽  
...  
Keyword(s):  
Mediterranean Sea ◽  
Size Composition ◽  
Demographic Structure ◽  
Depth Stratum ◽  
Abundance Indices ◽  
The Mediterranean ◽  
Spatio Temporal ◽  
Wide Geographic Distribution ◽  
Temporal Basis ◽  
Trawl Surveys

Information on distribution, relative abundance and size composition of the pleuronectiform species Citharus linguatula, Lepidorhombus boscii and Solea vulgaris was obtained during the MEDITS trawl surveys, carried out in a wide area of the Mediterranean Sea from 1994 to 1999. The three species showed a wide geographic distribution, as they were collected in all the macro-areas investigated, but with some differences in degree of presence among the 40 geographic sectors. Variations in abundance indices, analysed on a spatio-temporal basis with a Generalised Linear Model, were mostly related to the depth stratum and the macro-area. C. linguatula and S. vulgaris were especially found from 10 to 100 m depth, while L. boscii was most abundant on bottoms ranging from 100 to 500 m depth. The three species showed the highest abundance indices (kg/km2) in the Gulf of Lions, in the Greek Seas and along the Sardinian coasts. Especially for L. boscii and C. linguatula, the demographic structure showed that the sampled populations were mainly constituted by juveniles. The lowest biomass and abundance indices were obtained for S. vulgaris, whose catch was mainly composed of adult fish.

Bayesian electromagnetic spatio-temporal imaging of extended sources with Markov Random Field and temporal basis expansion

NeuroImage ◽  
2016 ◽  
Vol 139 ◽  
pp. 385-404 ◽  
Author(s):  
Ke Liu ◽  
Zhu Liang Yu ◽  
Wei Wu ◽  
Zhenghui Gu ◽  
Yuanqing Li ◽  
...  
Keyword(s):  
Random Field ◽  
Markov Random Field ◽  
Basis Expansion ◽  
Markov Random ◽  
Extended Sources ◽  
Spatio Temporal ◽  
Temporal Basis

scholarly journals Distribution and abundance of Eledone cirrhosa (Lamarck, 1798) and Eledone moschata (Lamarck, 1798) (Cephalopoda: Octopoda) in the Mediterranean Sea

2002 ◽  
Vol 66 (S2) ◽  
pp. 143 ◽  
Author(s):  
Paola Belcari ◽  
Georges Tserpes ◽  
María González ◽  
Eugenia Lefkaditou ◽  
Bojan Marceta ◽  
...  
Keyword(s):  
Depth Distribution ◽  
Size Composition ◽  
Major Area ◽  
Frequency Distributions ◽  
The Mediterranean ◽  
Spatio Temporal ◽  
Wide Geographic Distribution ◽  
Temporal Basis ◽  
The Mediterranean Basin ◽  
Trawl Surveys

Information on distribution, abundance and size composition of the two octopods Eledone cirrhosa and E. moschata was obtained from the MEDITS trawl surveys, carried out in a wide area of the Mediterranean basin from 1994 to 1999. Both species showed a wide geographic distribution, as they were collected in all the major areas investigated. E. cirrhosa showed a wide depth distribution, down to the 800 m isobath, while E. moschata was mostly restricted to within 200 m. Further analysis on spatio-temporal basis with a Generalised Linear Model, evidenced that differences among major areas, depth strata and their interaction were always significant. In the case of E. cirrhosa, differences among years and year-major area interaction were also significant. Two cohorts can be singled out in the size frequency distributions of E. cirrhosa, whereas only one mode can be clearly distinguished in most of the length distributions of E. moschata.

E3 ubiquitin ligases

2005 ◽  
Vol 41 ◽  
pp. 15-30 ◽  
Author(s):  
Helen C. Ardley ◽  
Philip A. Robinson
Keyword(s):  
Protein Complexes ◽  
Loss Of Function ◽  
Direct Role ◽  
Cellular Processes ◽  
Substrate Protein ◽  
Protein Ubiquitination ◽  
C Terminus ◽  
Full Complement ◽  
Spatio Temporal ◽  
Eukaryotic Organisms

The selectivity of the ubiquitin–26 S proteasome system (UPS) for a particular substrate protein relies on the interaction between a ubiquitin-conjugating enzyme (E2, of which a cell contains relatively few) and a ubiquitin–protein ligase (E3, of which there are possibly hundreds). Post-translational modifications of the protein substrate, such as phosphorylation or hydroxylation, are often required prior to its selection. In this way, the precise spatio-temporal targeting and degradation of a given substrate can be achieved. The E3s are a large, diverse group of proteins, characterized by one of several defining motifs. These include a HECT (homologous to E6-associated protein C-terminus), RING (really interesting new gene) or U-box (a modified RING motif without the full complement of Zn2+-binding ligands) domain. Whereas HECT E3s have a direct role in catalysis during ubiquitination, RING and U-box E3s facilitate protein ubiquitination. These latter two E3 types act as adaptor-like molecules. They bring an E2 and a substrate into sufficiently close proximity to promote the substrate's ubiquitination. Although many RING-type E3s, such as MDM2 (murine double minute clone 2 oncoprotein) and c-Cbl, can apparently act alone, others are found as components of much larger multi-protein complexes, such as the anaphase-promoting complex. Taken together, these multifaceted properties and interactions enable E3s to provide a powerful, and specific, mechanism for protein clearance within all cells of eukaryotic organisms. The importance of E3s is highlighted by the number of normal cellular processes they regulate, and the number of diseases associated with their loss of function or inappropriate targeting.

Elucidating cyclic AMP signaling in subcellular domains with optogenetic tools and fluorescent biosensors

2019 ◽  
Vol 47 (6) ◽  
pp. 1733-1747 ◽  
Author(s):  
Christina Klausen ◽  
Fabian Kaiser ◽  
Birthe Stüven ◽  
Jan N. Hansen ◽  
Dagmar Wachten
Keyword(s):  
Cyclic Amp ◽  
Adenosine Monophosphate ◽  
Adenylyl Cyclases ◽  
Temporal Precision ◽  
Fluorescent Biosensors ◽  
Subcellular Domains ◽  
Spatio Temporal ◽  
Hydrolysis Of ◽  
Shed Light ◽  
Cyclic Amp Signaling

The second messenger 3′,5′-cyclic nucleoside adenosine monophosphate (cAMP) plays a key role in signal transduction across prokaryotes and eukaryotes. Cyclic AMP signaling is compartmentalized into microdomains to fulfil specific functions. To define the function of cAMP within these microdomains, signaling needs to be analyzed with spatio-temporal precision. To this end, optogenetic approaches and genetically encoded fluorescent biosensors are particularly well suited. Synthesis and hydrolysis of cAMP can be directly manipulated by photoactivated adenylyl cyclases (PACs) and light-regulated phosphodiesterases (PDEs), respectively. In addition, many biosensors have been designed to spatially and temporarily resolve cAMP dynamics in the cell. This review provides an overview about optogenetic tools and biosensors to shed light on the subcellular organization of cAMP signaling.

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